Selective apoptosis of breast cancer cells by siRNA targeting of BORIS.
about
Widespread expression of BORIS/CTCFL in normal and cancer cellsDifferent Effects of BORIS/CTCFL on Stemness Gene Expression, Sphere Formation and Cell Survival in Epithelial Cancer Stem CellsThe cancer-associated CTCFL/BORIS protein targets multiple classes of genomic repeats, with a distinct binding and functional preference for humanoid-specific SVA transposable elementsBrother of Regulator of Imprinted Sites (BORIS) suppresses apoptosis in colorectal cancer.BORIS (CTCFL) is not expressed in most human breast cell lines and high grade breast carcinomasGlycerol-3-phosphate acyltranferase-2 behaves as a cancer testis gene and promotes growth and tumorigenicity of the breast cancer MDA-MB-231 cell line.Targeting the epigenome in malignant pleural mesotheliomaNon-viral nanocarriers for siRNA delivery in breast cancer.BORIS/CTCFL-mediated transcriptional regulation of the hTERT telomerase gene in testicular and ovarian tumor cellsIntravenous ascorbic acid to prevent and treat cancer-associated sepsis?BORIS/CTCFL is an RNA-binding protein that associates with polysomes.Transcription factor BORIS (Brother of the Regulator of Imprinted Sites) directly induces expression of a cancer-testis antigen, TSP50, through regulated binding of BORIS to the promoterCancer-testis antigen, BORIS based vaccine delivered by dendritic cells is extremely effective against a very aggressive and highly metastatic mouse mammary carcinoma.Expression of the epigenetic factor BORIS (CTCFL) in the human genomeAcceleration of pro-caspase-3 maturation and cell migration inhibition in human breast cancer cells by phytoconstituents of Rheum emodi rhizome extractsHeat shock protein 70-2 (HSP70-2) overexpression in breast cancerCancer testes antigens in breast cancer: biological role, regulation, and therapeutic applicability.The cancer-testis antigen BORIS phenocopies the tumor suppressor CTCF in normal and neoplastic cells.Down-regulation of C35 decreased the cell viability and migration of breast ductal carcinoma cells.Functional roles of CTCF in breast cancer.Intragenic DNA methylation and BORIS-mediated cancer-specific splicing contribute to the Warburg effect.Investigation of fusion gene expression in HCT116 cells.BORIS: a key regulator of cancer stemness
P2860
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P2860
Selective apoptosis of breast cancer cells by siRNA targeting of BORIS.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
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2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
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2008年學術文章
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name
Selective apoptosis of breast cancer cells by siRNA targeting of BORIS.
@en
type
label
Selective apoptosis of breast cancer cells by siRNA targeting of BORIS.
@en
prefLabel
Selective apoptosis of breast cancer cells by siRNA targeting of BORIS.
@en
P2093
P1476
Selective apoptosis of breast cancer cells by siRNA targeting of BORIS.
@en
P2093
Anahit Ghochikyan
Boris N Reznik
Christopher J Dougherty
Gary Reznik
Liping Liu
Michael G Agadjanyan
Thomas E Ichim
Wei-Ping Min
P304
P356
10.1016/J.BBRC.2008.03.040
P577
2008-03-18T00:00:00Z