Ribotoxic stress response: activation of the stress-activated protein kinase JNK1 by inhibitors of the peptidyl transferase reaction and by sequence-specific RNA damage to the alpha-sarcin/ricin loop in the 28S rRNA.
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TANK potentiates tumor necrosis factor receptor-associated factor-mediated c-Jun N-terminal kinase/stress-activated protein kinase activation through the germinal center kinase pathwayRibosomal protein L23 activates p53 by inhibiting MDM2 function in response to ribosomal perturbation but not to translation inhibitionDiverse functions of RNase L and implications in pathologyDifferential role of basal keratinocytes in UV-induced immunosuppression and skin cancerA scientific journey through the 2-5A/RNase L systemD-MEKK1, the Drosophila orthologue of mammalian MEKK4/MTK1, and Hemipterous/D-MKK7 mediate the activation of D-JNK by cadmium and arsenite in Schneider cells.Shiga Toxins as Multi-Functional Proteins: Induction of Host Cellular Stress Responses, Role in Pathogenesis and Therapeutic ApplicationsRole of apoptosis in diseaseActivation of cell stress response pathways by Shiga toxinsFusion toxin BLyS-gelonin inhibits growth of malignant human B cell lines in vitro and in vivoThe isolation and characterization of temperature-dependent ricin A chain molecules in Saccharomyces cerevisiaePerturbation of rRNA synthesis in the bap28 mutation leads to apoptosis mediated by p53 in the zebrafish central nervous systemSuppression of ribosomal function triggers innate immune signaling through activation of the NLRP3 inflammasomeIdentification of small molecules that suppress ricin-induced stress-activated signaling pathwaysDexamethasone rescues neurovascular unit integrity from cell damage caused by systemic administration of shiga toxin 2 and lipopolysaccharide in mice motor cortexPuromycin selectively increases mdr1a expression in immortalized rat brain endothelial cell linesDiversity and impact of prokaryotic toxins on aquatic environments: a reviewA novel role of cytosolic protein synthesis inhibition in aminoglycoside ototoxicity.Ricin A-chain requires c-Jun N-terminal kinase to induce apoptosis in nontransformed epithelial cells.Memory consolidation in both trace and delay fear conditioning is disrupted by intra-amygdala infusion of the protein synthesis inhibitor anisomycin.Co-exposure to low doses of the food contaminants deoxynivalenol and nivalenol has a synergistic inflammatory effect on intestinal explants.Inhibition of prefrontal protein synthesis following recall does not disrupt memory for trace fear conditioning.c-Jun N-terminal kinase (JNK) cooperates with Gsk3beta to regulate Dishevelled-mediated microtubule stability.Shiga toxins stimulate secretion of interleukin-8 from intestinal epithelial cells.Administration of ricin induces a severe inflammatory response via nonredundant stimulation of ERK, JNK, and P38 MAPK and provides a mouse model of hemolytic uremic syndrome.Mouse model of hemolytic-uremic syndrome caused by endotoxin-free Shiga toxin 2 (Stx2) and protection from lethal outcome by anti-Stx2 antibody.Endothelial damage induced by Shiga toxins delivered by neutrophils during transmigration.Escherichia coli Shiga Toxin Mechanisms of Action in Renal Disease.Activation of the Classical Mitogen-Activated Protein Kinases Is Part of the Shiga Toxin-Induced Ribotoxic Stress Response and May Contribute to Shiga Toxin-Induced Inflammation.Verotoxin and ricin have novel effects on preproendothelin-1 expression but fail to modify nitric oxide synthase (ecNOS) expression and NO production in vascular endothelium.A genome-wide screen in Saccharomyces cerevisiae reveals a critical role for the mitochondria in the toxicity of a trichothecene mycotoxinShiga toxin-induced tumor necrosis factor alpha expression: requirement for toxin enzymatic activity and monocyte protein kinase C and protein tyrosine kinasesRNase L-independent specific 28S rRNA cleavage in murine coronavirus-infected cellsMalaria parasite mutants with altered erythrocyte permeability: a new drug resistance mechanism and important molecular tool.Global protein phosphorylation dynamics during deoxynivalenol-induced ribotoxic stress response in the macrophage.Development of a quantitative RT-PCR assay to examine the kinetics of ribosome depurination by ribosome inactivating proteins using Saccharomyces cerevisiae as a model.Induction of apoptosis by Shiga toxins.The MAP kinase-activated protein kinase 2 (MK2) contributes to the Shiga toxin-induced inflammatory responseTherapeutic effects of glutamic acid in piglets challenged with deoxynivalenolEffect of shiga toxin and its subunits on cytokine induction in different cell lines.
P2860
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P2860
Ribotoxic stress response: activation of the stress-activated protein kinase JNK1 by inhibitors of the peptidyl transferase reaction and by sequence-specific RNA damage to the alpha-sarcin/ricin loop in the 28S rRNA.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Ribotoxic stress response: act ...... in/ricin loop in the 28S rRNA.
@en
type
label
Ribotoxic stress response: act ...... in/ricin loop in the 28S rRNA.
@en
prefLabel
Ribotoxic stress response: act ...... in/ricin loop in the 28S rRNA.
@en
P2093
P2860
P356
P1476
Ribotoxic stress response: act ...... in/ricin loop in the 28S rRNA.
@en
P2093
J A Pearson
M S Iordanov
P2860
P304
P356
10.1128/MCB.17.6.3373
P407
P577
1997-06-01T00:00:00Z