Trastuzumab signaling in ErbB2-overexpressing inflammatory breast cancer correlates with X-linked inhibitor of apoptosis protein expression.
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Could the eIF2α-Independent Translation Be the Achilles Heel of Cancer?Targeting Mortalin by Embelin Causes Activation of Tumor Suppressor p53 and Deactivation of Metastatic Signaling in Human Breast Cancer CellsTargeting GLI1 expression in human inflammatory breast cancer cells enhances apoptosis and attenuates migration.Monoclonal antibody against the ectodomain of E-cadherin (DECMA-1) suppresses breast carcinogenesis: involvement of the HER/PI3K/Akt/mTOR and IAP pathwaysInflammatory breast cancer tumor emboli express high levels of anti-apoptotic proteins: use of a quantitative high content and high-throughput 3D IBC spheroid assay to identify targeting strategiesChallenging a Misnomer? The Role of Inflammatory Pathways in Inflammatory Breast CancerX-linked inhibitor of apoptosis protein inhibits apoptosis in inflammatory breast cancer cells with acquired resistance to an ErbB1/2 tyrosine kinase inhibitor.Differential effects of arsenic trioxide on chemosensitization in human hepatic tumor and stellate cell linesImmunologic targeting of FOXP3 in inflammatory breast cancer cells.Targeted apoptotic effects of thymoquinone and tamoxifen on XIAP mediated Akt regulation in breast cancerXIAP antagonist embelin inhibited proliferation of cholangiocarcinoma cells.Mn porphyrin in combination with ascorbate acts as a pro-oxidant and mediates caspase-independent cancer cell death.IRES-mediated translation of cellular messenger RNA operates in eIF2α- independent manner during stress.Disulfiram (DSF) acts as a copper ionophore to induce copper-dependent oxidative stress and mediate anti-tumor efficacy in inflammatory breast cancer.Anoikis evasion in inflammatory breast cancer cells is mediated by Bim-EL sequestrationNew approach to develop ultra-high inhibitory drug using the power function of the stoichiometry of the targeted nanomachine or biocomplex.Anti-HER3 domain 1 and 3 antibodies reduce tumor growth by hindering HER2/HER3 dimerization and AKT-induced MDM2, XIAP, and FoxO1 phosphorylation.X-linked inhibitor of apoptosis protein mediates tumor cell resistance to antibody-dependent cellular cytotoxicity.ErbB1/2 tyrosine kinase inhibitor mediates oxidative stress-induced apoptosis in inflammatory breast cancer cells.Quantitative high-throughput efficacy profiling of approved oncology drugs in inflammatory breast cancer models of acquired drug resistance and re-sensitization.Targeting inhibitor of apoptosis proteins in combination with ErbB antagonists in breast cancer.MLH1 expression sensitises ovarian cancer cells to cell death mediated by XIAP inhibition.Drug-screening and genomic analyses of HER2-positive breast cancer cell lines reveal predictors for treatment responseEmbelin - a drug of antiquity: shifting the paradigm towards modern medicine.Discovery of a new method for potent drug development using power function of stoichiometry of homomeric biocomplexes or biological nanomotorsBisphenol A activates EGFR and ERK promoting proliferation, tumor spheroid formation and resistance to EGFR pathway inhibition in estrogen receptor-negative inflammatory breast cancer cells.Embelin inhibits growth and induces apoptosis through the suppression of Akt/mTOR/S6K1 signaling cascades.GW583340 and GW2974, human EGFR and HER-2 inhibitors, reverse ABCG2- and ABCB1-mediated drug resistance.XIAP over-expression is an independent poor prognostic marker in Middle Eastern breast cancer and can be targeted to induce efficient apoptosisEmbelin-induced apoptosis of HepG2 human hepatocellular carcinoma cells and blockade of HepG2 cells in the G2/M phase via the mitochondrial pathway.Screening in larval zebrafish reveals tissue-specific distribution of fifteen fluorescent compounds.Embelin-induced MCF-7 breast cancer cell apoptosis and blockade of MCF-7 cells in the G2/M phase via the mitochondrial pathway.Tissue microarray analysis of X-linked inhibitor of apoptosis (XIAP) expression in breast cancer patients.Smac mimetic Birinapant induces apoptosis and enhances TRAIL potency in inflammatory breast cancer cells in an IAP-dependent and TNF-α-independent mechanism.Photothermal ablation of inflammatory breast cancer tumor emboli using plasmonic gold nanostars.Photothermal ablation of inflammatory breast cancer tumor emboli using plasmonic gold nanostars.Delivery of Synthetic mRNA Encoding FOXP3 Antigen into Dendritic Cells for Inflammatory Breast Cancer Immunotherapy.Embelin suppresses dendritic cell functions and limits autoimmune encephalomyelitis through the TGF-β/β-catenin and STAT3 signaling pathways.
P2860
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P2860
Trastuzumab signaling in ErbB2-overexpressing inflammatory breast cancer correlates with X-linked inhibitor of apoptosis protein expression.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Trastuzumab signaling in ErbB2 ...... apoptosis protein expression.
@en
type
label
Trastuzumab signaling in ErbB2 ...... apoptosis protein expression.
@en
prefLabel
Trastuzumab signaling in ErbB2 ...... apoptosis protein expression.
@en
P2093
P1476
Trastuzumab signaling in ErbB2 ...... apoptosis protein expression.
@en
P2093
Aris Baras
Gayathri R Devi
Herbert K Lyerly
Junping Wei
Katherine M Aird
Michael A Morse
Timothy Clay
Xiuyun Ding
P356
10.1158/1535-7163.MCT-07-0370
P577
2008-01-01T00:00:00Z