The constitutively active orphan G-protein-coupled receptor GPR39 protects from cell death by increasing secretion of pigment epithelium-derived growth factor.
about
G protein-coupled receptor 39 deficiency is associated with pancreatic islet dysfunctionProteomics-derived cerebrospinal fluid markers of autopsy-confirmed Alzheimer's disease.Overexpression of GPR39 contributes to malignant development of human esophageal squamous cell carcinoma.The cystine/glutamate antiporter system x(c)(-) in health and disease: from molecular mechanisms to novel therapeutic opportunities.GPR39 activates proliferation and differentiation of porcine intramuscular preadipocytes through targeting the PI3K/AKT cell signaling pathway.Cell and molecular biology underpinning the effects of PEDF on cancers in general and osteosarcoma in particular.The plasma membrane channel ORAI1 mediates detrimental calcium influx caused by endogenous oxidative stress.Mitochondrial function and energy metabolism in neuronal HT22 cells resistant to oxidative stress.Network for activation of human endothelial cells by oxidized phospholipids: a critical role of heme oxygenase 1.GPR39 receptors and actions of trace metals on pancreatic beta cell function and glucose homoeostasis.Protein kinase inhibitor β enhances the constitutive activity of G-protein-coupled zinc receptor GPR39.The ZnR/GPR39 interacts with the CaSR to enhance signaling in prostate and salivary epithelia.The role of Ca2+ in cell death caused by oxidative glutamate toxicity and ferroptosis.β-Cell Specific Overexpression of GPR39 Protects against Streptozotocin-Induced HyperglycemiaMolecular mechanism of Zn2+ agonism in the extracellular domain of GPR39.Discovery of 2-Pyridylpyrimidines as the First Orally Bioavailable GPR39 Agonists.Zinc Metabolism and Metallothioneins.Oxytosis/Ferroptosis-(Re-) Emerging Roles for Oxidative Stress-Dependent Non-apoptotic Cell Death in Diseases of the Central Nervous System.
P2860
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P2860
The constitutively active orphan G-protein-coupled receptor GPR39 protects from cell death by increasing secretion of pigment epithelium-derived growth factor.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
The constitutively active orph ...... thelium-derived growth factor.
@en
type
label
The constitutively active orph ...... thelium-derived growth factor.
@en
prefLabel
The constitutively active orph ...... thelium-derived growth factor.
@en
P2093
P2860
P356
P1476
The constitutively active orph ...... thelium-derived growth factor.
@en
P2093
Ambrish Saxena
Ana-Luisa Pina
Andreas Geerts
Anna Pantlen
Axel Methner
Diamandis Toutzaris
Mert Sahin
Sonja Dittmer
Stefan Golz
P2860
P304
P356
10.1074/JBC.M704323200
P407
P577
2008-01-07T00:00:00Z