A novel mechanism for the control of translation initiation by amino acids, mediated by phosphorylation of eukaryotic initiation factor 2B.
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Changes in translational control after pro-apoptotic stressEctopic expression of eIF2Bepsilon in rat skeletal muscle rescues the sepsis-induced reduction in guanine nucleotide exchange activity and protein synthesisIdentification of residues that underpin interactions within the eukaryotic initiation factor (eIF2) 2B complexeIF2 interactions with initiator tRNA and eIF2B are regulated by post-translational modifications and conformational dynamicsToll-like receptor activation suppresses ER stress factor CHOP and translation inhibition through activation of eIF2B.Conserved upstream open reading frames in higher plants.Fusel alcohols regulate translation initiation by inhibiting eIF2B to reduce ternary complex in a mechanism that may involve altering the integrity and dynamics of the eIF2B body.Simvastatin represses protein synthesis in the muscle-derived C₂C₁₂ cell line with a concomitant reduction in eukaryotic initiation factor 2B expressionActivation of glycogen synthase kinase 3β ameliorates diabetes-induced kidney injury.mRNA translation and protein synthesis: an analysis of different modelling methodologies and a new PBN based approach.A systems view of the protein expression process.The High-Risk Human Papillomavirus E6 Oncogene Exacerbates the Negative Effect of Tryptophan Starvation on the Development of Chlamydia trachomatis.Specificity of amino acid regulated gene expression: analysis of genes subjected to either complete or single amino acid deprivationGSK3β regulates AKT-induced central nervous system axon regeneration via an eIF2Bε-dependent, mTORC1-independent pathway.ATF4 induction through an atypical integrated stress response to ONC201 triggers p53-independent apoptosis in hematological malignancies.Crystal structure of the C-terminal domain of the ɛ subunit of human translation initiation factor eIF2B.Regulation of muscle protein synthesis and the effects of catabolic states.Translation factors and ribosomal proteins control tumor onset and progression: how?Amino acids and autophagy: cross-talk and co-operation to control cellular homeostasis.Functional analysis of recently identified mutations in eukaryotic translation initiation factor 2Bɛ (eIF2Bɛ) identified in Chinese patients with vanishing white matter disease.Re-evaluating the roles of proposed modulators of mammalian target of rapamycin complex 1 (mTORC1) signaling.Does enteral protein administration stimulate duodenal mucosa protein synthesis through an mTORC1-independent signaling pathway?Severity of vanishing white matter disease does not correlate with deficits in eIF2B activity or the integrity of eIF2B complexes.Blocking eukaryotic initiation factor 4F complex formation does not inhibit the mTORC1-dependent activation of protein synthesis in cardiomyocytes.Immobilization induces anabolic resistance in human myofibrillar protein synthesis with low and high dose amino acid infusion.
P2860
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P2860
A novel mechanism for the control of translation initiation by amino acids, mediated by phosphorylation of eukaryotic initiation factor 2B.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
A novel mechanism for the cont ...... karyotic initiation factor 2B.
@en
type
label
A novel mechanism for the cont ...... karyotic initiation factor 2B.
@en
prefLabel
A novel mechanism for the cont ...... karyotic initiation factor 2B.
@en
P2860
P356
P1476
A novel mechanism for the cont ...... karyotic initiation factor 2B.
@en
P2093
Xuemin Wang
P2860
P304
P356
10.1128/MCB.01512-07
P407
P577
2007-12-26T00:00:00Z