Eukaryotic initiation factor 2B: identification of multiple phosphorylation sites in the epsilon-subunit and their functions in vivo
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Mutations linked to leukoencephalopathy with vanishing white matter impair the function of the eukaryotic initiation factor 2B complex in diverse waysEukaryotic translation-initiation factor eIF2beta binds to protein kinase CK2: effects on CK2alpha activityFibronectin controls cap-dependent translation through beta1 integrin and eukaryotic initiation factors 4 and 2 coordinated pathwaysEvidence that the dephosphorylation of Ser(535) in the epsilon-subunit of eukaryotic initiation factor (eIF) 2B is insufficient for the activation of eIF2B by insulinThe C terminus of initiation factor 4E-binding protein 1 contains multiple regulatory features that influence its function and phosphorylationMutations causing childhood ataxia with central nervous system hypomyelination reduce eukaryotic initiation factor 2B complex formation and activityBacterial phosphoproteomic analysis reveals the correlation between protein phosphorylation and bacterial pathogenicityIs there an optimal time for warfighters to supplement with protein?Structure of the catalytic fragment of translation initiation factor 2B and identification of a critically important catalytic residueCrystal structure of yeast Ypr118w, a methylthioribose-1-phosphate isomerase related to regulatory eIF2B subunits.Characterization of the minimal catalytic domain within eIF2B: the guanine-nucleotide exchange factor for translation initiationRole of translation initiation factor 2B in control of cell survival by the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3beta signaling pathwayGSK-3: Functional Insights from Cell Biology and Animal Models.Alterations in skeletal muscle cell homeostasis in a mouse model of cigarette smoke exposure.Inhibition of ERK1/2 Restores GSK3β Activity and Protein Synthesis Levels in a Model of Tuberous Sclerosis.Translational deregulation in PDK-1-/- embryonic stem cellsThe emerging role of guanine nucleotide exchange factors in ALS and other neurodegenerative diseases.Transduction of growth or mitogenic signals into translational activation of TOP mRNAs is fully reliant on the phosphatidylinositol 3-kinase-mediated pathway but requires neither S6K1 nor rpS6 phosphorylationDYRK2 negatively regulates cardiomyocyte growth by mediating repressor function of GSK-3β on eIF2Bε.What Are the bona fide GSK3 Substrates?Lithium blocks the c-Jun stress response and protects neurons via its action on glycogen synthase kinase 3.Rapid turnover of mcl-1 couples translation to cell survival and apoptosis.Change in nutritional status modulates the abundance of critical pre-initiation intermediate complexes during translation initiation in vivoDynamic cycling of eIF2 through a large eIF2B-containing cytoplasmic body: implications for translation controlGlycogen synthase kinase 3 (GSK3) in the heart: a point of integration in hypertrophic signalling and a therapeutic target? A critical analysisVesicular stomatitis virus oncolysis of T lymphocytes requires cell cycle entry and translation initiation.GSK3β regulates AKT-induced central nervous system axon regeneration via an eIF2Bε-dependent, mTORC1-independent pathway.Evidence of placental translation inhibition and endoplasmic reticulum stress in the etiology of human intrauterine growth restriction.Phosphoproteomics Profiling of Tobacco Mature Pollen and Pollen Activated in vitro.Crystal structure of the C-terminal domain of the ɛ subunit of human translation initiation factor eIF2B.High-throughput screening of the yeast kinome: identification of human serine/threonine protein kinases that phosphorylate the hepatitis C virus NS5A protein.Differential phosphorylation of plant translation initiation factors by Arabidopsis thaliana CK2 holoenzymes.Regulation of mRNA translation by signaling pathwaysSignaling crosstalk between the mTOR complexes.The translation initiation factor eIF2beta is an interactor of protein phosphatase-1.A novel mechanism for the control of translation initiation by amino acids, mediated by phosphorylation of eukaryotic initiation factor 2B.PKR and PKR-like endoplasmic reticulum kinase induce the proteasome-dependent degradation of cyclin D1 via a mechanism requiring eukaryotic initiation factor 2alpha phosphorylation.Calcineurin complex isolated from T-cell acute lymphoblastic leukemia (T-ALL) cells identifies new signaling pathways including mTOR/AKT/S6K whose inhibition synergize with calcineurin inhibition to promote T-ALL cell death.Farnesol inhibits translation to limit growth and filamentation in C. albicans and S. cerevisiae.Protein Translation and Signaling in Human Eosinophils
P2860
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P2860
Eukaryotic initiation factor 2B: identification of multiple phosphorylation sites in the epsilon-subunit and their functions in vivo
description
2001 nî lūn-bûn
@nan
2001 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Eukaryotic initiation factor 2 ...... it and their functions in vivo
@ast
Eukaryotic initiation factor 2 ...... it and their functions in vivo
@en
Eukaryotic initiation factor 2 ...... it and their functions in vivo
@en-gb
Eukaryotic initiation factor 2 ...... it and their functions in vivo
@nl
type
label
Eukaryotic initiation factor 2 ...... it and their functions in vivo
@ast
Eukaryotic initiation factor 2 ...... it and their functions in vivo
@en
Eukaryotic initiation factor 2 ...... it and their functions in vivo
@en-gb
Eukaryotic initiation factor 2 ...... it and their functions in vivo
@nl
prefLabel
Eukaryotic initiation factor 2 ...... it and their functions in vivo
@ast
Eukaryotic initiation factor 2 ...... it and their functions in vivo
@en
Eukaryotic initiation factor 2 ...... it and their functions in vivo
@en-gb
Eukaryotic initiation factor 2 ...... it and their functions in vivo
@nl
P2093
P2860
P3181
P356
P1433
P1476
Eukaryotic initiation factor 2 ...... it and their functions in vivo
@en
P2093
P2860
P304
P3181
P356
10.1093/EMBOJ/20.16.4349
P407
P577
2001-08-15T00:00:00Z