Ubiquitination and degradation of Tal1/SCL are induced by notch signaling and depend on Skp2 and CHIP.
about
Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancerTargeting the oncogenic E3 ligase Skp2 in prostate and breast cancer cells with a novel energy restriction-mimetic agentNotch and transforming growth factor-beta (TGFbeta) signaling pathways cooperatively regulate vascular smooth muscle cell differentiation.Fli-1 overexpression in hematopoietic progenitors deregulates T cell development and induces pre-T cell lymphoblastic leukaemia/lymphoma.Melanoma antigen gene protein-A11 (MAGE-11) F-box links the androgen receptor NH2-terminal transactivation domain to p160 coactivators.Role of helix-loop-helix proteins during differentiation of erythroid cells.CHIP stabilizes amyloid precursor protein via proteasomal degradation and p53-mediated trans-repression of β-secretase.Notch-regulated periphery B cell differentiation involves suppression of E protein function.The E3 ligase CHIP: insights into its structure and regulation.The ubiquitin ligase CHIP regulates c-Myc stability and transcriptional activity.Ubc13 and COOH terminus of Hsp70-interacting protein (CHIP) are required for growth hormone receptor endocytosis.A novel function of cIAP1 as a mediator of CHIP-driven eIF4E regulation.Notch-induced Asb2 expression promotes protein ubiquitination by forming non-canonical E3 ligase complexes.Inhibition of the hTERT promoter by the proto-oncogenic protein TAL1.
P2860
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P2860
Ubiquitination and degradation of Tal1/SCL are induced by notch signaling and depend on Skp2 and CHIP.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Ubiquitination and degradation ...... g and depend on Skp2 and CHIP.
@en
type
label
Ubiquitination and degradation ...... g and depend on Skp2 and CHIP.
@en
prefLabel
Ubiquitination and degradation ...... g and depend on Skp2 and CHIP.
@en
P2093
P2860
P356
P1476
Ubiquitination and degradation ...... g and depend on Skp2 and CHIP.
@en
P2093
Huaqing Wu
Xiao-Hong Sun
P2860
P304
P356
10.1074/JBC.M704981200
P407
P577
2007-10-25T00:00:00Z