Insulin modulates gluconeogenesis by inhibition of the coactivator TORC2.
about
SIK2 is a centrosome kinase required for bipolar mitotic spindle formation that provides a potential target for therapy in ovarian cancerNuclear export regulation of COP1 by 14-3-3σ in response to DNA damageCryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesisCOP9 signalosome subunit 6 stabilizes COP1, which functions as an E3 ubiquitin ligase for 14-3-3σDAX-1 acts as a novel corepressor of orphan nuclear receptor HNF4alpha and negatively regulates gluconeogenic enzyme gene expressionTORC2, a coactivator of cAMP-response element-binding protein, promotes Epstein-Barr virus reactivation from latency through interaction with viral BZLF1 proteinE3 ubiquitin ligase COP1 regulates the stability and functions of MTA1A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchangeEnergy metabolism in the liverFeeding state, insulin and NPR-1 modulate chemoreceptor gene expression via integration of sensory and circuit inputsTATN-1 mutations reveal a novel role for tyrosine as a metabolic signal that influences developmental decisions and longevity in Caenorhabditis elegansKnock-in Luciferase Reporter Mice for In Vivo Monitoring of CREB ActivityThe interplay between obesity and cancer: a fly viewThere is Kisspeptin - And Then There is KisspeptinRegulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2Creb coactivators direct anabolic responses and enhance performance of skeletal muscleGlucagon regulates gluconeogenesis through KAT2B- and WDR5-mediated epigenetic effectsCdc2-like kinase 2 is an insulin-regulated suppressor of hepatic gluconeogenesisSuppressor of MEK null (SMEK)/protein phosphatase 4 catalytic subunit (PP4C) is a key regulator of hepatic gluconeogenesisFeeding and Fasting Signals Converge on the LKB1-SIK3 Pathway to Regulate Lipid Metabolism in DrosophilaCREB coactivator CRTC2/TORC2 and its regulator calcineurin crucially mediate follicle-stimulating hormone and transforming growth factor β1 upregulation of steroidogenesisNovel liver-specific TORC2 siRNA corrects hyperglycemia in rodent models of type 2 diabetesTCF7L2 modulates glucose homeostasis by regulating CREB- and FoxO1-dependent transcriptional pathway in the liverSalt-inducible kinase regulates hepatic lipogenesis by controlling SREBP-1c phosphorylationThe Creb1 coactivator Crtc1 is required for energy balance and fertilityActivation of TORC1 transcriptional coactivator through MEKK1-induced phosphorylationThe UPS in diabetes and obesity.Gs-DREADD Knock-In Mice for Tissue-Specific, Temporal Stimulation of Cyclic AMP SignalingModeling inherited metabolic disorders of the liver using human induced pluripotent stem cells.Physiological regulation of Akt activity and stability.Targeted disruption of the CREB coactivator Crtc2 increases insulin sensitivity.Involvement of transducer of regulated cAMP response element-binding protein activity on corticotropin releasing hormone transcription.Control of steroid 21-oic acid synthesis by peroxisome proliferator-activated receptor alpha and role of the hypothalamic-pituitary-adrenal axisCyclin D1-Cdk4 controls glucose metabolism independently of cell cycle progressionImpact of dietary polyphenols on carbohydrate metabolism.Cell-type specific expression of a dominant negative PKA mutation in mice.Role of the SIK2-p35-PJA2 complex in pancreatic β-cell functional compensation.Interaction between salt-inducible kinase 2 and protein phosphatase 2A regulates the activity of calcium/calmodulin-dependent protein kinase I and protein phosphatase methylesterase-1.Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state.Rasd1 modulates the coactivator function of NonO in the cyclic AMP pathway.
P2860
Q24295146-F0D1F374-37EE-4E93-8AD9-294DDA77F686Q24299752-AAD5E4D5-54E6-46D2-9C3F-4E157D29BF59Q24300249-184388D5-C1B3-463C-AD32-30322FA74524Q24304964-69863493-BB3E-4432-98A7-5A084565FFBBQ24320012-14E795BF-2703-4908-B297-E224257540CEQ24320081-461BC3EF-0658-47FD-ABAF-7BD5040B9118Q24322010-36A7E247-E4D5-49D2-B1FB-7ED0383062AAQ24648525-63EFF184-9D30-4A96-B50D-7FFD7B374266Q26996783-52F16355-AF76-4471-896F-B251740E5671Q27312401-B103D3F7-6885-4478-93ED-D9122C18F9D4Q27318316-3D1ADE38-4D06-4893-9324-AC6C8733C131Q27335935-84D03753-CD84-4C65-BC7C-DC3D53CD5F4DQ28079088-31034246-6488-4C9C-974E-D6B522482E9EQ28088549-2DDD665B-5DB5-4F45-893B-977D6AA350AEQ28272571-C34C3913-7753-439D-956D-0E2BADFBEBA4Q28507328-24D60F7C-F8E9-464A-91C7-C5FABFF85BD8Q28507540-521EE4A2-59F5-4ADC-BB37-52A2A0878A43Q28511396-5E175952-EBD5-47C0-A4BB-BBE95FE2500EQ28512561-724F454E-0535-4AEE-80E3-D760A2523AC9Q28547387-CAF864D1-95EA-40E0-B3CA-DE92064962F6Q28566945-28D133EB-709A-4F7F-B393-D42F73B3FD28Q28583617-E082BDE3-07A2-4B3B-90A8-9BFC65E7CC2DQ28589957-EA52F5E3-6C08-42E6-BEAA-1D28B152ACA8Q28592678-AF2282F6-4708-4273-8F52-D409877612BAQ30439853-2195CC67-DE54-4276-9351-97ED517B727DQ30440587-99C9E189-E3EC-411F-985E-14E145B17DA6Q33384293-B7E83C20-449D-42EC-BA4E-791E354E1E32Q33571975-6E601253-046B-4242-B74E-01ECCF631F40Q33672762-114FEF4B-D481-471F-AA5B-AE0E6BD6CDF7Q33680673-1E2ABB2F-8980-42ED-8DA4-800535CD0AD9Q33733839-0AD416D0-F121-4DF5-AA79-34D37E6F3CB7Q33735555-D1311C8C-4146-4F23-A0B8-EE9F1739F7F6Q33748207-12E4E2BF-7330-47B5-BF96-E4B80B55FB68Q33827309-5AE7D40A-E131-4E72-AF48-885B1847F0FBQ33853862-6862687A-CC8C-4032-A2C5-2DA1E6F80DF5Q33886919-A9861506-2770-4252-9FB9-6C96270979B3Q33936173-FFD76A80-1AB0-4AD9-BE69-4158C74275A6Q33947256-DD6729E1-9B9B-4FA7-B217-3BD199E1E252Q33968008-4B2669B1-66DC-4439-818D-FA025DC55AD8Q34019011-02A96C0E-785D-4DD0-B32E-7107877210C3
P2860
Insulin modulates gluconeogenesis by inhibition of the coactivator TORC2.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Insulin modulates gluconeogenesis by inhibition of the coactivator TORC2.
@en
type
label
Insulin modulates gluconeogenesis by inhibition of the coactivator TORC2.
@en
prefLabel
Insulin modulates gluconeogenesis by inhibition of the coactivator TORC2.
@en
P2093
P921
P356
P1433
P1476
Insulin modulates gluconeogenesis by inhibition of the coactivator TORC2.
@en
P2093
John Yates
Jose Heredia
Marc Montminy
Renaud Dentin
Seung-Hoi Koo
Susan Hedrick
Thomas Vargas
P2888
P304
P356
10.1038/NATURE06128
P407
P577
2007-09-05T00:00:00Z
P5875
P6179
1037591099