Cytochrome P450 enzyme levels in HepG2 cells and cryopreserved primary human hepatocytes and their induction in HepG2 cells.
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Cytotoxicity effect of degraded and undegraded kappa and iota carrageenan in human intestine and liver cell linesMicrofabricated mammalian organ systems and their integration into models of whole animals and humansHepatic toxicology following single and multiple exposure of engineered nanomaterials utilising a novel primary human 3D liver microtissue modelThe extreme variety of genotoxic response to benzo[a]pyrene in three different human cell lines from three different organsCYP450 Enzymes Effect Oxygen-Dependent Reduction of Azide-Based Fluorogenic DyesCytotoxic and antioxidant properties of active principals isolated from water hyacinth against four cancer cells linesRelating hepatocellular carcinoma tumor samples and cell lines using gene expression data in translational researchIntegrating transcriptomics and metabonomics to unravel modes-of-action of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in HepG2 cells.Defined plant extracts can protect human cells against combined xenobiotic effectsGymnaster koraiensis and its major components, 3,5-di-O-caffeoylquinic acid and gymnasterkoreayne B, reduce oxidative damage induced by tert-butyl hydroperoxide or acetaminophen in HepG2 cellsBis(hydroxyphenyl)methane-bisphenol F-metabolism by the HepG2 human hepatoma cell line and cryopreserved human hepatocytes.Genetic variability of drug-metabolizing enzymes: the dual impact on psychiatric therapy and regulation of brain function.Present state and future perspectives of using pluripotent stem cells in toxicology researchCytochrome P450 induction properties of food and herbal-derived compounds using a novel multiplex RT-qPCR in vitro assay, a drug-food interaction prediction toolSimilarities and differences in the expression of drug-metabolizing enzymes between human hepatic cell lines and primary human hepatocytes.Alcohol disrupts endoplasmic reticulum function and protein secretion in hepatocytes.Alteration in the expression of cytochrome P450s (CYP1A1, CYP2E1, and CYP3A11) in the liver of mouse induced by microcystin-LR.Study of Cytotoxic Effects of Benzonitrile PesticidesEvaluation of geno-toxicity of methyl parathion and chlorpyrifos to human liver carcinoma cell line (HepG2).Genome-Wide Pharmacogenomic Study on Methadone Maintenance Treatment Identifies SNP rs17180299 and Multiple Haplotypes on CYP2B6, SPON1, and GSG1L Associated with Plasma Concentrations of Methadone R- and S-enantiomers in Heroin-Dependent Patients.Sesamin: A Naturally Occurring Lignan Inhibits CYP3A4 by Antagonizing the Pregnane X Receptor Activation.Cytotoxic Synergy Between Cytokines and NSAIDs Associated With Idiosyncratic Hepatotoxicity Is Driven by Mitogen-Activated Protein KinasesInfluence of a three-dimensional, microarray environment on human cell culture in drug screening systems.Hepatic Cyp2d and Cyp26a1 mRNAs and activities are increased during mouse pregnancy.An in vitro model of human acute ethanol exposure that incorporates CXCR3- and CXCR4-dependent recruitment of immune cellsCalcium Contributes to the Cytotoxic Interaction Between Diclofenac and CytokinesBiological models for phytochemical research: from cell to human organism.Current industrial practices in assessing CYP450 enzyme induction: preclinical and clinicalComparison of Liver Cell Models Using the Basel Phenotyping Cocktail.Zebularine upregulates expression of CYP genes through inhibition of DNMT1 and PKR in HepG2 cells.Pungent ginger components modulates human cytochrome P450 enzymes in vitro.Methods for the quantitative evaluation and prediction of CYP enzyme induction using human in vitro systems.Human variation and risk assessment: microarray and other studies utilizing human hepatocytes and human liver subcellular preparations.High-content analysis in toxicology: screening substances for human toxicity potential, elucidating subcellular mechanisms and in vivo use as translational safety biomarkers.Scientific concepts and applications of integrated discrete multiple organ co-culture technology.Downregulation of cytochrome P450 2C8 by 3-methylcholanthrene in human hepatocellular carcinoma cell lines.In vitro genotoxicity of carcinogenic asarone isomers.Bisphenol a induces steatosis in HepaRG cells using a model of perinatal exposure.High Content Analysis of Human Pluripotent Stem Cell Derived Hepatocytes Reveals Drug Induced Steatosis and Phospholipidosis.A three-dimensional collagen-sponge-based culture system coated with simplified recombinant fibronectin improves the function of a hepatocyte cell line.
P2860
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P2860
Cytochrome P450 enzyme levels in HepG2 cells and cryopreserved primary human hepatocytes and their induction in HepG2 cells.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Cytochrome P450 enzyme levels ...... heir induction in HepG2 cells.
@en
type
label
Cytochrome P450 enzyme levels ...... heir induction in HepG2 cells.
@en
prefLabel
Cytochrome P450 enzyme levels ...... heir induction in HepG2 cells.
@en
P1433
P1476
Cytochrome P450 enzyme levels ...... heir induction in HepG2 cells.
@en
P2093
Walter M A Westerink
Willem G E J Schoonen
P304
P356
10.1016/J.TIV.2007.05.014
P577
2007-06-08T00:00:00Z