Functional redundancy of GSK-3alpha and GSK-3beta in Wnt/beta-catenin signaling shown by using an allelic series of embryonic stem cell lines.
about
Interactome mapping of the phosphatidylinositol 3-kinase-mammalian target of rapamycin pathway identifies deformed epidermal autoregulatory factor-1 as a new glycogen synthase kinase-3 interactorThe EDD E3 ubiquitin ligase ubiquitinates and up-regulates beta-catenin.Glycogen synthase kinase 3: more than a namesakeGlycogen synthase kinase 3: a point of convergence for the host inflammatory responseWnt/beta-catenin signaling and small molecule inhibitorsWnt/beta-catenin signaling: components, mechanisms, and diseasesMaintaining embryonic stem cell pluripotency with Wnt signalingGlycogen synthase kinase-3β is a pivotal mediator of cancer invasion and resistance to therapyReview of pharmacological treatment in mood disorders and future directions for drug development.Ex uno plures: molecular designs for embryonic pluripotencyThe GSK-3 family as therapeutic target for myocardial diseasesGSK-3 as potential target for therapeutic intervention in cancerGlycogen synthase kinase-3 inhibition enhances translation of pluripotency-associated transcription factors to contribute to maintenance of mouse embryonic stem cell self-renewalStructural basis of GSK-3 inhibition by N-terminal phosphorylation and by the Wnt receptor LRP6Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regenerationEmbryonic NANOG activity defines colorectal cancer stem cells and modulates through AP1- and TCF-dependent mechanismsThe β-catenin destruction complexNovel reporter alleles of GSK-3α and GSK-3βFrat is a phosphatidylinositol 3-kinase/Akt-regulated determinant of glycogen synthase kinase 3β subcellular localization in pluripotent cellsGSK3A is redundant with GSK3B in modulating drug resistance and chemotherapy-induced necroptosisHigher Matrix Stiffness Upregulates Osteopontin Expression in Hepatocellular Carcinoma Cells Mediated by Integrin β1/GSK3β/β-Catenin Signaling PathwayMechanism of Resistance and Novel Targets Mediating Resistance to EGFR and c-Met Tyrosine Kinase Inhibitors in Non-Small Cell Lung CancerInhibitory phosphorylation of GSK-3 by CaMKII couples depolarization to neuronal survivalPhosphatidylinositol 3-kinase (PI3K) signaling via glycogen synthase kinase-3 (Gsk-3) regulates DNA methylation of imprinted lociGSK-3alpha directly regulates beta-adrenergic signaling and the response of the heart to hemodynamic stress in miceExit from pluripotency is gated by intracellular redistribution of the bHLH transcription factor Tfe3Esrrb is a pivotal target of the Gsk3/Tcf3 axis regulating embryonic stem cell self-renewalThe ground state of embryonic stem cell self-renewalNeurodevelopment in schizophrenia: the role of the wnt pathways.GSK-3: Functional Insights from Cell Biology and Animal Models.Is glycogen synthase kinase-3 a central modulator in mood regulation?Cdc42 and Gsk3 modulate the dynamics of radial glial growth, inter-radial glial interactions and polarity in the developing cerebral cortex.Inhibition of GSK3 phosphorylation of beta-catenin via phosphorylated PPPSPXS motifs of Wnt coreceptor LRP6.Glycogen synthase kinase-3 inhibition disrupts nuclear factor-kappaB activity in pancreatic cancer, but fails to sensitize to gemcitabine chemotherapyHepatocyte growth factor (Hgf) stimulates low density lipoprotein receptor-related protein (Lrp) 5/6 phosphorylation and promotes canonical Wnt signalingTissue-specific analysis of glycogen synthase kinase-3α (GSK-3α) in glucose metabolism: effect of strain variation.GSK3beta: role in therapeutic landscape and development of modulators.The liberation of embryonic stem cells.Conditional cell reprogramming involves non-canonical β-catenin activation and mTOR-mediated inactivation of Akt.GSK-3 signaling in developing cortical neurons is essential for radial migration and dendritic orientation.
P2860
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P2860
Functional redundancy of GSK-3alpha and GSK-3beta in Wnt/beta-catenin signaling shown by using an allelic series of embryonic stem cell lines.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Functional redundancy of GSK-3 ...... of embryonic stem cell lines.
@en
type
label
Functional redundancy of GSK-3 ...... of embryonic stem cell lines.
@en
prefLabel
Functional redundancy of GSK-3 ...... of embryonic stem cell lines.
@en
P2093
P2860
P1433
P1476
Functional redundancy of GSK-3 ...... of embryonic stem cell lines.
@en
P2093
Geoffrey A Wood
Lisa K Kockeritz
Satish Patel
P2860
P304
P356
10.1016/J.DEVCEL.2007.04.001
P407
P577
2007-06-01T00:00:00Z