The threonine that carries fucose, but not fucose, is required for Cripto to facilitate Nodal signaling.
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Slc35c2 promotes Notch1 fucosylation and is required for optimal Notch signaling in mammalian cellsEmerging roles of nodal and Cripto-1: from embryogenesis to breast cancer progressionFringe-mediated extension of O-linked fucose in the ligand-binding region of Notch1 increases binding to mammalian Notch ligandsO-fucosylation of the notch ligand mDLL1 by POFUT1 is dispensable for ligand functionEffects of varying Notch1 signal strength on embryogenesis and vasculogenesis in compound mutant heterozygotes.O-GlcNAc on NOTCH1 EGF repeats regulates ligand-induced Notch signaling and vascular development in mammalsO-fucose modulates Notch-controlled blood lineage commitment.Targeting the embryonic gene Cripto-1 in cancer and beyond.O-glucose trisaccharide is present at high but variable stoichiometry at multiple sites on mouse Notch1.Regulation of Notch signaling by glycosylation.The O-fucose glycan in the ligand-binding domain of Notch1 regulates embryogenesis and T cell development.Cripto promotes A-P axis specification independently of its stimulatory effect on Nodal autoinduction.Engineering of mucin-type human glycoproteins in yeast cells.In vivo consequences of deleting EGF repeats 8-12 including the ligand binding domain of mouse Notch1.Myeloproliferation and hematopoietic stem cell dysfunction due to defective Notch receptor modification by O-fucose glycans.Roles of Pofut1 and O-fucose in mammalian Notch signaling.Biochemical and Cellular Analysis Reveals Ligand Binding Specificities, a Molecular Basis for Ligand Recognition, and Membrane Association-dependent Activities of Cripto-1 and Cryptic.What Have We Learned from Glycosyltransferase Knockouts in Mice?Activation of a Nodal-independent signaling pathway by Cripto-1 mutants with impaired activation of a Nodal-dependent signaling pathwayO-fucosylation of muscle agrin determines its ability to cluster acetylcholine receptors.Novel roles for O-linked glycans in protein folding.
P2860
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P2860
The threonine that carries fucose, but not fucose, is required for Cripto to facilitate Nodal signaling.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
The threonine that carries fuc ...... to facilitate Nodal signaling.
@en
type
label
The threonine that carries fuc ...... to facilitate Nodal signaling.
@en
prefLabel
The threonine that carries fuc ...... to facilitate Nodal signaling.
@en
P2093
P2860
P356
P1476
The threonine that carries fuc ...... to facilitate Nodal signaling.
@en
P2093
Changhui Ge
Pamela Stanley
Robert S Haltiwanger
Shaolin Shi
Xinghua Hou
P2860
P304
20133-20141
P356
10.1074/JBC.M702593200
P407
P577
2007-05-15T00:00:00Z