DNA-binding activity of simian virus 40 large T antigen correlates with a distinct phosphorylation state.
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Dephosphorylation of simian virus 40 large-T antigen and p53 protein by protein phosphatase 2A: inhibition by small-t antigenProtein phosphatase 2A dephosphorylates simian virus 40 large T antigen specifically at residues involved in regulation of DNA-binding activityActivation of SV40 DNA replication in vitro by cellular protein phosphatase 2ASimian virus 40 large T antigen: the puzzle, the pieces, and the emerging pictureBinding of p110 retinoblastoma protein inhibits nuclear import of simian virus SV40 large tumor antigen.Two phosphorylated subclasses of polyomavirus large T antigen that differ in their modes of association with the cell nucleusRegulation of SV40 DNA replication by phosphorylation of T antigenProduction of simian virus 40 large tumor antigen in bacteria: altered DNA-binding specificity and dna-replication activity of underphosphorylated large tumor antigen.Development of quantitative and high-throughput assays of polyomavirus and papillomavirus DNA replicationStructure of the origin-binding domain of simian virus 40 large T antigen bound to DNA.Analysis of a large-T-antigen variant expressed in simian virus 40-transformed mouse cell line mKS-A.Quantitative analysis of the binding of simian virus 40 large T antigen to DNA.Simian virus 40 small-t antigen stimulates viral DNA replication in permissive monkey cells.Properties of the DNA-binding domain of the simian virus 40 large T antigen.The human DNA-activated protein kinase phosphorylates simian virus 40 T antigen at amino- and carboxy-terminal sites.Isolation and characterization of a viable adenovirus mutant defective in nuclear transport of the DNA-binding proteinAlterations in the structure of new and old forms of simian virus 40 large T antigen (T) defined by age-dependent epitope changes: new T is the same as ATPase-active T.Linker insertion mutants of simian virus 40 large T antigen that show trans-dominant interference with wild-type large T antigen map to multiple sites within the T-antigen gene.Phosphorylation in vitro of Escherichia coli-produced 235R and 266R tumor antigens encoded by human adenovirus type 12 early transformation region 1A.Simian virus 40 large T antigen oligomers: analysis of electrophoresis in the absence of detergent.DNA-binding region of the simian virus 40 tumor antigenReplication and transformation functions of in vitro-generated simian virus 40 large T antigen mutantsGenetic mapping of a major site of phosphorylation in adenovirus type 2 E1A proteins.Phosphorylation downregulates the DNA-binding activity of simian virus 40 T antigen.Simian virus 40 (SV40) T antigen binds specifically to double-stranded DNA but not to single-stranded DNA or DNA/RNA hybrids containing the SV40 regulatory sequences.Expression and complex formation of simian virus 40 large T antigen and mouse p53 in insect cells.trans-dominant defective mutants of simian virus 40 T antigen.Abundant synthesis of functional human T-cell leukemia virus type I p40x protein in eucaryotic cells by using a baculovirus expression vectorLocalization of the phosphorylations of polyomavirus large T antigen.Differential phosphorylation of cytoplasmic and nuclear variants of simian virus 40 large T antigen encoded by simian virus 40-adenovirus 7 hybrid viruses.Studies on the origin-specific DNA-binding domain of simian virus 40 large T antigenRemoval of serine phosphates from simian virus 40 large T antigen increases its ability to stimulate DNA replication in vitro but has no effect on ATPase and DNA bindingBiochemical characterization of phosphorylation site mutants of simian virus 40 large T antigen: evidence for interaction between amino- and carboxy-terminal domains.Mutations in the phosphorylation sites of simian virus 40 (SV40) T antigen alter its origin DNA-binding specificity for sites I or II and affect SV40 DNA replication activity.Two regions of simian virus 40 T antigen determine cooperativity of double-hexamer assembly on the viral origin of DNA replication and promote hexamer interactions during bidirectional origin DNA unwinding.Phosphorylation of simian virus 40 T antigen on Thr 124 selectively promotes double-hexamer formation on subfragments of the viral core origin.Altered phosphorylation of free and bound forms of monkey p53 and simian virus 40 large T antigen during lytic infection.Biochemical characterization of Epstein-Barr virus nuclear antigen 2A.Altered phosphorylation pattern of simian virus 40 T antigen expressed in insect cells by using a baculovirus vector.The finger domain of simian virus 40 large T antigen controls DNA-binding specificity.
P2860
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P2860
DNA-binding activity of simian virus 40 large T antigen correlates with a distinct phosphorylation state.
description
1984 nî lūn-bûn
@nan
1984年の論文
@ja
1984年論文
@yue
1984年論文
@zh-hant
1984年論文
@zh-hk
1984年論文
@zh-mo
1984年論文
@zh-tw
1984年论文
@wuu
1984年论文
@zh
1984年论文
@zh-cn
name
DNA-binding activity of simian ...... istinct phosphorylation state.
@en
type
label
DNA-binding activity of simian ...... istinct phosphorylation state.
@en
prefLabel
DNA-binding activity of simian ...... istinct phosphorylation state.
@en
P2093
P2860
P1433
P1476
DNA-binding activity of simian ...... istinct phosphorylation state.
@en
P2093
P2860
P407
P577
1984-04-01T00:00:00Z