Silencing and complementation of reovirus core protein mu2: functional correlations with mu2-microtubule association and differences between virus- and plasmid-derived mu2.
about
Virus-mediated compartmentalization of the host translational machinery.A post-entry step in the mammalian orthoreovirus replication cycle is a determinant of cell tropism.Engineering recombinant reoviruses with tandem repeats and a tetravirus 2A-like element for exogenous polypeptide expressionIdentification of functional domains in reovirus replication proteins muNS and mu2.Genome packaging of reovirus is mediated by the scaffolding property of the microtubule network.Sequestration of free tubulin molecules by the viral protein NSP2 induces microtubule depolymerization during rotavirus infection.Formation of the factory matrix is an important, though not a sufficient function of nonstructural protein mu NS during reovirus infection.Dissection of mammalian orthoreovirus µ2 reveals a self-associative domain required for binding to microtubules but not to factory matrix protein µNS.Characterization of a replicating mammalian orthoreovirus with tetracysteine tagged μNS for live cell visualization of viral factories.Reovirus mu2 protein inhibits interferon signaling through a novel mechanism involving nuclear accumulation of interferon regulatory factor 9.
P2860
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P2860
Silencing and complementation of reovirus core protein mu2: functional correlations with mu2-microtubule association and differences between virus- and plasmid-derived mu2.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Silencing and complementation ...... irus- and plasmid-derived mu2.
@en
type
label
Silencing and complementation ...... irus- and plasmid-derived mu2.
@en
prefLabel
Silencing and complementation ...... irus- and plasmid-derived mu2.
@en
P2093
P2860
P1433
P1476
Silencing and complementation ...... irus- and plasmid-derived mu2.
@en
P2093
John Carvalho
Max L Nibert
Michelle M Arnold
P2860
P304
P356
10.1016/J.VIROL.2007.03.037
P407
P577
2007-04-23T00:00:00Z