The M1 gene is associated with differences in the temperature optimum of the transcriptase activity in reovirus core particles
about
Comparisons of the M1 genome segments and encoded mu2 proteins of different reovirus isolatesReovirus polymerase λ3 localized by cryo-electron microscopy of virions at a resolution of 7.6 ÅBackbone model of an aquareovirus virion by cryo-electron microscopy and bioinformatics.Gene-specific inhibition of reovirus replication by RNA interference.Conformational changes accompany activation of reovirus RNA-dependent RNA transcription.The reovirus protein mu2, encoded by the M1 gene, is an RNA-binding protein.Trypsin-induced structural transformation in aquareovirusReovirus sigmaNS protein is required for nucleation of viral assembly complexes and formation of viral inclusions.Reovirus induction of and sensitivity to beta interferon in cardiac myocyte cultures correlate with induction of myocarditis and are determined by viral core proteins.Reovirus core protein mu2 determines the filamentous morphology of viral inclusion bodies by interacting with and stabilizing microtubules.A post-entry step in the mammalian orthoreovirus replication cycle is a determinant of cell tropism.Functional investigation of grass carp reovirus nonstructural protein NS80.Reovirus-induced acute myocarditis in mice correlates with viral RNA synthesis rather than generation of infectious virus in cardiac myocytes.Reovirus-induced apoptosis of MDCK cells is not linked to viral yield and is blocked by Bcl-2.Characterization of grass carp reovirus minor core protein VP4.Identification of functional domains in reovirus replication proteins muNS and mu2.HeLa cell response proteome alterations induced by mammalian reovirus T3D infection.Reovirus replication protein μ2 influences cell tropism by promoting particle assembly within viral inclusions.The reovirus mutant tsA279 L2 gene is associated with generation of a spikeless core particle: implications for capsid assembly.The hydrophilic amino-terminal arm of reovirus core shell protein lambda1 is dispensable for particle assembly.Identification and characterization of a double-stranded RNA- reovirus temperature-sensitive mutant defective in minor core protein mu2Nonrandom segregation of parental alleles in reovirus reassortants.Characterization of an ATPase activity in reovirus cores and its genetic association with core-shell protein lambda1Core protein mu2 is a second determinant of nucleoside triphosphatase activities by reovirus cores.Localization of a C-terminal region of lambda2 protein in reovirus cores.Increased ubiquitination and other covariant phenotypes attributed to a strain- and temperature-dependent defect of reovirus core protein mu2.Dissection of mammalian orthoreovirus µ2 reveals a self-associative domain required for binding to microtubules but not to factory matrix protein µNS.Silencing and complementation of reovirus core protein mu2: functional correlations with mu2-microtubule association and differences between virus- and plasmid-derived mu2.Avian reovirus temperature-sensitive mutant tsA12 has a lesion in major core protein sigmaA and is defective in assembly.Inhibition of reovirus by mycophenolic acid is associated with the M1 genome segment.Reovirus nonstructural protein mu NS recruits viral core surface proteins and entering core particles to factory-like inclusions.Conserved sequence motifs for nucleoside triphosphate binding unique to turreted reoviridae members and coltiviruses.
P2860
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P2860
The M1 gene is associated with differences in the temperature optimum of the transcriptase activity in reovirus core particles
description
1996 nî lūn-bûn
@nan
1996 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
The M1 gene is associated with ...... ity in reovirus core particles
@ast
The M1 gene is associated with ...... ity in reovirus core particles
@en
type
label
The M1 gene is associated with ...... ity in reovirus core particles
@ast
The M1 gene is associated with ...... ity in reovirus core particles
@en
prefLabel
The M1 gene is associated with ...... ity in reovirus core particles
@ast
The M1 gene is associated with ...... ity in reovirus core particles
@en
P2093
P2860
P1433
P1476
The M1 gene is associated with ...... ity in reovirus core particles
@en
P2093
P2860
P304
P407
P577
1996-02-01T00:00:00Z