GRP78/BiP inhibits endoplasmic reticulum BIK and protects human breast cancer cells against estrogen starvation-induced apoptosis.
about
The endoplasmic reticulum stress response in aging and age-related diseasesRegulation of AKT phosphorylation at Ser473 and Thr308 by endoplasmic reticulum stress modulates substrate specificity in a severity dependent mannerEssential role of the unfolded protein response regulator GRP78/BiP in protection from neuronal apoptosisCancer Microenvironment and Endoplasmic Reticulum Stress ResponseMechanisms of disseminated cancer cell dormancy: an awakening fieldCrystal Structures of the ATPase Domains of Four Human Hsp70 Isoforms: HSPA1L/Hsp70-hom, HSPA2/Hsp70-2, HSPA6/Hsp70B', and HSPA5/BiP/GRP78ER chaperones in mammalian development and human diseasesRegulation of PERK signaling and leukemic cell survival by a novel cytosolic isoform of the UPR regulator GRP78/BiPFunctional investigation of NCI-H460-inducible myofibroblasts on the chemoresistance to VP-16 with a microfluidic 3D co-culture deviceKnockdown of ERp57 increases BiP/GRP78 induction and protects against hyperoxia and tunicamycin-induced apoptosis.Misfolding, Aggregation, and Disordered Segments in c-Abl and p53 in Human Cancer.IRES inhibition induces terminal differentiation and synchronized death in triple-negative breast cancer and glioblastoma cellsA long non-coding RNA signature to improve prognosis prediction of colorectal cancer.Cab45S inhibits the ER stress-induced IRE1-JNK pathway and apoptosis via GRP78/BiP.The dual role of calcium as messenger and stressor in cell damage, death, and survival.The Par-4-GRP78 TRAIL, more twists and turns.Restoration of visual function in P23H rhodopsin transgenic rats by gene delivery of BiP/Grp78CAF-derived HGF promotes cell proliferation and drug resistance by up-regulating the c-Met/PI3K/Akt and GRP78 signalling in ovarian cancer cells.Transcriptional induction of GRP78/BiP by histone deacetylase inhibitors and resistance to histone deacetylase inhibitor-induced apoptosis.Protein alterations associated with temozolomide resistance in subclones of human glioblastoma cell lines.GRP78 as potential predictor for breast cancer response to adjuvant taxane therapy.ERLIN2 promotes breast cancer cell survival by modulating endoplasmic reticulum stress pathways.Endoplasmic reticulum stress and cancer.Calreticulin expression in infiltrating ductal breast carcinomas: relationships with disease progression and humoral immune responses.Endoplasmic reticulum stress in endometrial cancer.Pharmacological induction of cell surface GRP78 contributes to apoptosis in triple negative breast cancer cellsNovel mechanism of anti-apoptotic function of 78-kDa glucose-regulated protein (GRP78): endocrine resistance factor in breast cancer, through release of B-cell lymphoma 2 (BCL-2) from BCL-2-interacting killer (BIK).Knockdown of GRP78 promotes apoptosis in pancreatic acinar cells and attenuates the severity of cerulein and LPS induced pancreatic inflammation.HSP70s: From Tumor Transformation to Cancer Therapy.Two-layer modular analysis of gene and protein networks in breast cancer.Characterization and mechanism of stress-induced translocation of 78-kilodalton glucose-regulated protein (GRP78) to the cell surface.Anticipatory estrogen activation of the unfolded protein response is linked to cell proliferation and poor survival in estrogen receptor α-positive breast cancerA review of the mammalian unfolded protein response.Star-PAP control of BIK expression and apoptosis is regulated by nuclear PIPKIα and PKCδ signaling.Unfolding the Role of Stress Response Signaling in Endocrine Resistant Breast Cancers.Loss of soluble N-ethylmaleimide-sensitive factor attachment protein α (αSNAP) induces epithelial cell apoptosis via down-regulation of Bcl-2 expression and disruption of the GolgiGRP78 Protein Expression in Ovarian Cancer Patients and Perspectives for a Drug-Targeting Approach.Synergistic promotion of breast cancer cells death by targeting molecular chaperone GRP78 and heat shock protein 70.Blockade of GRP78 sensitizes breast cancer cells to microtubules-interfering agents that induce the unfolded protein response.Ligand-targeted theranostic nanomedicines against cancer
P2860
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P2860
GRP78/BiP inhibits endoplasmic reticulum BIK and protects human breast cancer cells against estrogen starvation-induced apoptosis.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
GRP78/BiP inhibits endoplasmic ...... starvation-induced apoptosis.
@en
type
label
GRP78/BiP inhibits endoplasmic ...... starvation-induced apoptosis.
@en
prefLabel
GRP78/BiP inhibits endoplasmic ...... starvation-induced apoptosis.
@en
P2093
P1433
P1476
GRP78/BiP inhibits endoplasmic ...... starvation-induced apoptosis.
@en
P2093
P304
P356
10.1158/0008-5472.CAN-06-4594
P407
P577
2007-04-01T00:00:00Z