Methylation of PTCH1, the Patched-1 gene, in a panel of primary medulloblastomas. - Wikidata - awgldk - TriplyDB

Methylation of PTCH1, the Patched-1 gene, in a panel of primary medulloblastomas.

Methylation of PTCH1, the Patched-1 gene, in a panel of primary medulloblastomas.

http://www.wikidata.org/entity/Q40145800

about

Pediatric medulloblastoma - update on molecular classification driving targeted therapies Arsenic trioxide inhibits human cancer cell growth and tumor development in mice by blocking Hedgehog/GLI pathway DNA methylation of developmental genes in pediatric medulloblastomas identified by denaturation analysis of methylation differences Regulation of sonic hedgehog-GLI1 downstream target genes PTCH1, Cyclin D2, Plakoglobin, PAX6 and NKX2.2 and their epigenetic status in medulloblastoma and astrocytoma.Overexpression of mutant Ptch in rhabdomyosarcomas is associated with promoter hypomethylation and increased Gli1 and H3K4me3 occupancy.Methylation of PTCH1a gene in a subset of gastric cancers The potential for epigenetic analysis of paediatric CNS tumours to improve diagnosis, treatment and prognosis.Detection and analysis of the methylation status of PTCH1 gene involved in the hedgehog signaling pathway in a human gastric cancer cell line.Molecular alterations in odontogenic keratocysts as potential therapeutic targets.Patched1 deletion increases N-Myc protein stability as a mechanism of medulloblastoma initiation and progression.Blocking the hedgehog pathway inhibits hepatoblastoma growth.Reproducibility of academic preclinical translational research: lessons from the development of Hedgehog pathway inhibitors to treat cancer

P2860

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P2860

Methylation of PTCH1, the Patched-1 gene, in a panel of primary medulloblastomas.

http://www.wikidata.org/entity/Q40145800

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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2008年论文

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2008年论文

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name

Methylation of PTCH1, the Patched-1 gene, in a panel of primary medulloblastomas.

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type

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Methylation of PTCH1, the Patched-1 gene, in a panel of primary medulloblastomas.

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prefLabel

Methylation of PTCH1, the Patched-1 gene, in a panel of primary medulloblastomas.

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J.CANCERGENCYTO.2007.09.008

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Cancer Genetics and Cytogenetics

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Methylation of PTCH1, the Patched-1 gene, in a panel of primary medulloblastomas.

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James M Olson

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Joel I Pritchard

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P2860

Epigenetic gene silencing in cancer – a mechanism for early oncogenic pathway addiction?

Epigenetic silencing of the HIC-1 gene in human medulloblastomas

Identification of tumour-specific epigenetic events in medulloblastoma development by hypermethylation profiling

Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog

Gene silencing in cancer in association with promoter hypermethylation

Prediction of central nervous system embryonal tumour outcome based on gene expression

BiQ Analyzer: visualization and quality control for DNA methylation data from bisulfite sequencing.

Transcriptional profiling of the Sonic hedgehog response: a critical role for N-myc in proliferation of neuronal precursors

Medulloblastoma: signalling a change in treatment.

Neural precursor cycling at sonic speed: N-Myc pedals, GSK-3 brakes.

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47-50

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scholarly article

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