Methylation of PTCH1, the Patched-1 gene, in a panel of primary medulloblastomas.
about
Pediatric medulloblastoma - update on molecular classification driving targeted therapiesArsenic trioxide inhibits human cancer cell growth and tumor development in mice by blocking Hedgehog/GLI pathwayDNA methylation of developmental genes in pediatric medulloblastomas identified by denaturation analysis of methylation differencesRegulation of sonic hedgehog-GLI1 downstream target genes PTCH1, Cyclin D2, Plakoglobin, PAX6 and NKX2.2 and their epigenetic status in medulloblastoma and astrocytoma.Overexpression of mutant Ptch in rhabdomyosarcomas is associated with promoter hypomethylation and increased Gli1 and H3K4me3 occupancy.Methylation of PTCH1a gene in a subset of gastric cancersThe potential for epigenetic analysis of paediatric CNS tumours to improve diagnosis, treatment and prognosis.Detection and analysis of the methylation status of PTCH1 gene involved in the hedgehog signaling pathway in a human gastric cancer cell line.Molecular alterations in odontogenic keratocysts as potential therapeutic targets.Patched1 deletion increases N-Myc protein stability as a mechanism of medulloblastoma initiation and progression.Blocking the hedgehog pathway inhibits hepatoblastoma growth.Reproducibility of academic preclinical translational research: lessons from the development of Hedgehog pathway inhibitors to treat cancer
P2860
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P2860
Methylation of PTCH1, the Patched-1 gene, in a panel of primary medulloblastomas.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Methylation of PTCH1, the Patched-1 gene, in a panel of primary medulloblastomas.
@en
type
label
Methylation of PTCH1, the Patched-1 gene, in a panel of primary medulloblastomas.
@en
prefLabel
Methylation of PTCH1, the Patched-1 gene, in a panel of primary medulloblastomas.
@en
P2860
P1476
Methylation of PTCH1, the Patched-1 gene, in a panel of primary medulloblastomas.
@en
P2093
James M Olson
Joel I Pritchard
P2860
P356
10.1016/J.CANCERGENCYTO.2007.09.008
P577
2008-01-01T00:00:00Z