Monoclonal antibody 4C5 immunostains human melanomas and inhibits melanoma cell invasion and metastasis.
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Extracellular Hsp90 (eHsp90) as the actual target in clinical trials: intentionally or unintentionallyThe regulatory mechanism of Hsp90alpha secretion and its function in tumor malignancyA novel extracellular Hsp90 mediated co-receptor function for LRP1 regulates EphA2 dependent glioblastoma cell invasionAberrant DNA damage response pathways may predict the outcome of platinum chemotherapy in ovarian cancerTargeting highly expressed extracellular HSP90 in breast cancer stem cells inhibits tumor growth in vitro and in vivo.Secretion of extracellular hsp90alpha via exosomes increases cancer cell motility: a role for plasminogen activation.Monoclonal antibody 4C5 prevents activation of MMP2 and MMP9 by disrupting their interaction with extracellular HSP90 and inhibits formation of metastatic breast cancer cell deposits.The 4C5 cell-impermeable anti-HSP90 antibody with anti-cancer activity, is composed of a single light chain dimerCell surface Cdc37 participates in extracellular HSP90 mediated cancer cell invasionThe regulatory mechanism of extracellular Hsp90{alpha} on matrix metalloproteinase-2 processing and tumor angiogenesisTumor-secreted Hsp90 subverts polycomb function to drive prostate tumor growth and invasion.Extracellular molecules involved in cancer cell invasionSelection and Characterization of Single Chain Antibody Fragments Specific for Hsp90 as a Potential Cancer Targeting Molecule.Patient-derived heavy chain antibody targets cell surface HSP90 on breast tumors.New developments in Hsp90 inhibitors as anti-cancer therapeutics: mechanisms, clinical perspective and more potential.Impact of heat-shock protein 90 on cancer metastasisA small molecule cell-impermeant Hsp90 antagonist inhibits tumor cell motility and invasion.Recent advances in the application of antibodies as therapeutics.The double-edged sword: conserved functions of extracellular hsp90 in wound healing and cancer.Effect of heat shock protein 90 (Hsp90) on migration and invasion of human cancer cells in vitro.PLCγ1-PKCγ signaling-mediated Hsp90α plasma membrane translocation facilitates tumor metastasis.Unconventional Secretion of Heat Shock Proteins in Cancer.Prox1 suppresses the proliferation of neuroblastoma cells via a dual action in p27-Kip1 and Cdc25A.Matrix metalloprotein-9 activation under cell-to-cell interaction between endothelial cells and monocytes: possible role of hypoxia and tumor necrosis factor-α.Anandamide increases the differentiation of rat adipocytes and causes PPARgamma and CB1 receptor upregulation.A critical role for HSP90 in cancer cell invasion involves interaction with the extracellular domain of HER-2.Inhibition of B16 murine melanoma metastasis and enhancement of immunity by fever-range whole body hyperthermia.Secreted heat shock protein 90 promotes prostate cancer stem cell heterogeneity.Detection and Analysis of Extracellular Hsp90 (eHsp90).Increased DNA double-strand breaks and enhanced apoptosis in patients with lupus nephritis.Inhibitory Effects of Far-Infrared Irradiation Generated by Ceramic Material on Murine Melanoma Cell Growth
P2860
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P2860
Monoclonal antibody 4C5 immunostains human melanomas and inhibits melanoma cell invasion and metastasis.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Monoclonal antibody 4C5 immuno ...... cell invasion and metastasis.
@en
type
label
Monoclonal antibody 4C5 immuno ...... cell invasion and metastasis.
@en
prefLabel
Monoclonal antibody 4C5 immuno ...... cell invasion and metastasis.
@en
P1476
Monoclonal antibody 4C5 immuno ...... a cell invasion and metastasis
@en
P2093
Andreas Karameris
Evangelia Patsavoudi
P304
P356
10.1158/1078-0432.CCR-06-1585
P407
P577
2007-03-01T00:00:00Z