Autoactivation of matriptase in vitro: requirement for biomembrane and LDL receptor domain. - Wikidata - awgldk - TriplyDB

Autoactivation of matriptase in vitro: requirement for biomembrane and LDL receptor domain.

Autoactivation of matriptase in vitro: requirement for biomembrane and LDL receptor domain.

http://www.wikidata.org/entity/Q40161979

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Structure of catalytic domain of Matriptase in complex with Sunflower trypsin inhibitor-1 Crystal Structures of Matriptase in Complex with Its Inhibitor Hepatocyte Growth Factor Activator Inhibitor-1 Matriptase autoactivation is tightly regulated by the cellular chemical environments Matriptase activation, an early cellular response to acidosis.Membrane-anchored serine proteases in vertebrate cell and developmental biology Targeting zymogen activation to control the matriptase-prostasin proteolytic cascade.Regulation of the matriptase-prostasin cell surface proteolytic cascade by hepatocyte growth factor activator inhibitor-1 during epidermal differentiation Matriptase is involved in ErbB-2-induced prostate cancer cell invasion Endogenous expression of matriptase in neural progenitor cells promotes cell migration and neuron differentiation.A pan-cancer analysis of alternative splicing events reveals novel tumor-associated splice variants of matriptase.Increased matriptase zymogen activation in inflammatory skin disorders.Combinatorial optimization of cystine-knot peptides towards high-affinity inhibitors of human matriptase-1 Detection of active matriptase using a biotinylated chloromethyl ketone peptide HAI-2 suppresses the invasive growth and metastasis of prostate cancer through regulation of matriptase.Matriptase is inhibited by extravascular antithrombin in epithelial cells but not in most carcinoma cells Ibuprofen regulates the expression and function of membrane-associated serine proteases prostasin and matriptase.Mechanisms for the control of matriptase activity in the absence of sufficient HAI-1 Energetic and structural basis for activation of the epithelial sodium channel by matriptase Natural Endogenous Human Matriptase and Prostasin Undergo Zymogen Activation via Independent Mechanisms in an Uncoupled Manner.Hepatocyte growth factor activator inhibitor-1 has a complex subcellular itinerary Prostasin is required for matriptase activation in intestinal epithelial cells to regulate closure of the paracellular pathway.Purification from human milk of matriptase complexes with secreted serpins: mechanism for inhibition of matriptase other than HAI-1.The cutting edge: membrane-anchored serine protease activities in the pericellular microenvironment.Matriptase activation and shedding through PDGF-D-mediated extracellular acidosis.Imbalanced matriptase pericellular proteolysis contributes to the pathogenesis of malignant B-cell lymphomas.Polarized epithelial cells secrete matriptase as a consequence of zymogen activation and HAI-1-mediated inhibition.Matriptase and prostasin are expressed in human skin in an inverse trend over the course of differentiation and are targeted to different regions of the plasma membrane.Matriptase: a culprit in cancer?Matriptase-2 (TMPRSS6): a proteolytic regulator of iron homeostasis The matriptase-prostasin proteolytic cascade in epithelial development and pathology.Regulation of pericellular proteolysis by hepatocyte growth factor activator inhibitor type 1 (HAI-1) in trophoblast cells.Strong expression association between matriptase and its substrate prostasin in breast cancer.Requirement of the activity of hepatocyte growth factor activator inhibitor type 1 for the extracellular appearance of a transmembrane serine protease matriptase in monkey kidney COS-1 cells.Defect of hepatocyte growth factor activator inhibitor type 1/serine protease inhibitor, Kunitz type 1 (Hai-1/Spint1) leads to ichthyosis-like condition and abnormal hair development in mice.Matriptase shedding is closely coupled with matriptase zymogen activation and requires de novo proteolytic cleavage likely involving its own activity.Roles of CUB and LDL receptor class A domain repeats of a transmembrane serine protease matriptase in its zymogen activation.The type II transmembrane serine protease matriptase cleaves the amyloid precursor protein and reduces its processing to β amyloid.Matriptase-2 mutations in iron-refractory iron deficiency anemia patients provide new insights into protease activation mechanisms.The Kunitz Domain I of Hepatocyte Growth Factor Activator Inhibitor-2 Inhibits Matriptase Activity and Invasive Ability of Human Prostate Cancer Cells.Alpha-1 Antitrypsin-Deficient Macrophages Have Increased Matriptase-Mediated Proteolytic Activity.

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P2860

Autoactivation of matriptase in vitro: requirement for biomembrane and LDL receptor domain.

http://www.wikidata.org/entity/Q40161979

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2007 nî lūn-bûn

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2007年の論文

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2007年学术文章

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2007年学术文章

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2007年學術文章

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2007年學術文章

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2007年學術文章

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Autoactivation of matriptase i ...... brane and LDL receptor domain.

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Autoactivation of matriptase i ...... brane and LDL receptor domain.

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Autoactivation of matriptase i ...... brane and LDL receptor domain.

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AJPCELL.00611.2006

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American Journal of Physiology - Cell Physiology

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Autoactivation of matriptase i ...... brane and LDL receptor domain.

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P2093

Chen-Yong Lin

http://www.w3.org/2001/XMLSchema#string

I-Chu Tseng

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Ken-ichi Kiyomiya

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Michael D Johnson

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Ming-Shyue Lee

http://www.w3.org/2001/XMLSchema#string

Robert B Dickson

http://www.w3.org/2001/XMLSchema#string

Youhong Wang

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P2860

Molecular cloning of cDNA for matriptase, a matrix-degrading serine protease with trypsin-like activity

Cellular localization of membrane-type serine protease 1 and identification of protease-activated receptor-2 and single-chain urokinase-type plasminogen activator as substrates

Hepatocyte growth factor activator inhibitor, a novel Kunitz-type serine protease inhibitor

Reverse biochemistry: use of macromolecular protease inhibitors to dissect complex biological processes and identify a membrane-type serine protease in epithelial cancer and normal tissue

Matriptase and HAI-1 are expressed by normal and malignant epithelial cells in vitro and in vivo

The epidermal barrier function is dependent on the serine protease CAP1/Prss8

High-resolution structure of a potent, cyclic proteinase inhibitor from sunflower seeds

Purification and characterization of a complex containing matriptase and a Kunitz-type serine protease inhibitor from human milk

Ovarian tumor cells express a transmembrane serine protease: a potential candidate for early diagnosis and therapeutic intervention

Type II transmembrane serine proteases. Insights into an emerging class of cell surface proteolytic enzymes

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C95-105

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10.1152/AJPCELL.00611.2006

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1

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293

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6463132

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17344310

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