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Structure of Influenza Virus N7: the Last Piece of the Neuraminidase"Jigsaw"PuzzleMammalian models for the study of H7 virus pathogenesis and transmission.Molecular determinants of influenza virus pathogenesis in mice.Mutations to PB2 and NP proteins of an avian influenza virus combine to confer efficient growth in primary human respiratory cells.Emerging influenza.Mammalian adaptive mutations of the PA protein of highly pathogenic avian H5N1 influenza virus.H5N1 influenza viruses: outbreaks and biological propertiesIntroduction of virulence markers in PB2 of pandemic swine-origin influenza virus does not result in enhanced virulence or transmission.Substitution of lysine at 627 position in PB2 protein does not change virulence of the 2009 pandemic H1N1 virus in miceThe ecology and adaptive evolution of influenza A interspecies transmissionAdaptation of pandemic H1N1 influenza viruses in mice.PB2 residue 158 is a pathogenic determinant of pandemic H1N1 and H5 influenza a viruses in mice.Combination of PB2 271A and SR polymorphism at positions 590/591 is critical for viral replication and virulence of swine influenza virus in cultured cells and in vivoHeterogeneous virulence of pandemic 2009 influenza H1N1 virus in miceA comparative study of short linear motif compositions of the influenza A virus ribonucleoproteinsGenomic and protein structural maps of adaptive evolution of human influenza A virus to increased virulence in the mouse.PB2 and hemagglutinin mutations are major determinants of host range and virulence in mouse-adapted influenza A virusMouse-adapted H9N2 influenza A virus PB2 protein M147L and E627K mutations are critical for high virulence.Characterization of an H10N8 influenza virus isolated from Dongting lake wetland.A combination of HA and PA mutations enhances virulence in a mouse-adapted H6N6 influenza A virus.Biochemical impact of the host adaptation-associated PB2 E627K mutation on the temperature-dependent RNA synthesis kinetics of influenza A virus polymerase complexAdaption of seasonal H1N1 influenza virus in mice.Pathology of Equine Influenza virus (H3N8) in Murine Model.Investigation of influenza virus polymerase activity in pig cells.Acquisition of a novel eleven amino acid insertion directly N-terminal to a tetrabasic cleavage site confers intracellular cleavage of an H7N7 influenza virus hemagglutinin.Pathogenicity of highly pathogenic avian influenza virus in mammalsAvian Influenza A virus polymerase association with nucleoprotein, but not polymerase assembly, is impaired in human cells during the course of infection.The effect of the PB2 mutation 627K on highly pathogenic H5N1 avian influenza virus is dependent on the virus lineage.Amino acid substitutions V63I or A37S/I61T/V63I/V100A in the PA N-terminal domain increase the virulence of H7N7 influenza A virus.Interspecies and intraspecies transmission of influenza A viruses: viral, host and environmental factors.Crucial role of PA in virus life cycle and host adaptation of influenza A virus.Influence of PB2 host-range determinants on the intranuclear mobility of the influenza A virus polymerase.Evidence for avian and human host cell factors that affect the activity of influenza virus polymerase.Prerequisites for the acquisition of mammalian pathogenicity by influenza A virus with a prototypic avian PB2 gene.The significance of avian influenza virus mouse-adaptation and its application in characterizing the efficacy of new vaccines and therapeutic agents.Adaptive mutations resulting in enhanced polymerase activity contribute to high virulence of influenza A virus in mice.Rapid emergence of a PB2-E627K substitution confers a virulent phenotype to an H9N2 avian influenza virus during adoption in mice.Characterization of low-pathogenic H6N6 avian influenza viruses in central China.A Single Amino Acid at the Polymerase Acidic Protein Determines the Pathogenicity of Influenza B Viruses.
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Adaptation of an H7N7 equine influenza A virus in mice.
@en
type
label
Adaptation of an H7N7 equine influenza A virus in mice.
@en
prefLabel
Adaptation of an H7N7 equine influenza A virus in mice.
@en
P2093
P356
P1476
Adaptation of an H7N7 equine influenza A virus in mice.
@en
P2093
Kyoko Shinya
Noriyuki Kasai
Shinji Watanabe
Toshihiro Ito
P304
P356
10.1099/VIR.0.82411-0
P407
P577
2007-02-01T00:00:00Z