Penicillinase active sites: labelling of serine-44 in beta-lactamase I by 6beta-bromopenicillanic acid.
about
Identification of the site of covalent attachment of nafcillin, a reversible suicide inhibitor of beta-lactamaseStructural Basis of the Inhibition of Class A β-Lactamases and Penicillin-Binding Proteins by 6-β-IodopenicillanateInactivation of the thiol RTEM-1 beta-lactamase by 6-beta-bromopenicillanic acid. Identity of the primary active-site nucleophileThe crystal structure of beta-lactamase from Staphylococcus aureus at 0.5 nm resolutionThe beta-lactamase of Enterobacter cloacae P99. Chemical properties, N-terminal sequence and interaction with 6 beta-halogenopenicillanatesInteraction of beta-iodopenicillanate with the beta-lactamases of Streptomyces albus G and Actinomadura R39Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase.Interaction of azthreonam and related monobactams with beta-lactamases from gram-negative bacteriaBiochemistry and comparative genomics of SxxK superfamily acyltransferases offer a clue to the mycobacterial paradox: presence of penicillin-susceptible target proteins versus lack of efficiency of penicillin as therapeutic agent.ampC cephalosporinase of Escherichia coli K-12 has a different evolutionary origin from that of beta-lactamases of the penicillinase typeSite-saturation studies of beta-lactamase: production and characterization of mutant beta-lactamases with all possible amino acid substitutions at residue 71Creation of a test plasmid for detecting G-C-to-T-A transversions by changing serine to arginine in the active site of beta-lactamase.Oligonucleotide-directed mutagenesis as a general and powerful method for studies of protein function.Mechanism of penicillin action: penicillin and substrate bind covalently to the same active site serine in two bacterial D-alanine carboxypeptidases.Sequences of the active-site peptides of three of the high-Mr penicillin-binding proteins of Escherichia coli K-12.Active-site serine mutants of the Streptomyces albus G beta-lactamase.beta-lactamase I from Bacillus cereus. Structure and site-directed mutagenesis.The potential use of mechanism-based enzyme inactivators in medicine.Beta-lactamases: molecular studies.Antibiotic resistance in pathogenic and producing bacteria, with special reference to beta-lactam antibiotics.Production of thiol-penicillin-binding protein 3 of Escherichia coli using a two primer method of site-directed mutagenesis.Kinetics of inactivation of beta-lactamase I by 6 beta-bromopenicillanic acid.Single-turnover and steady-state kinetics of hydrolysis of cephalosporins by beta-lactamase I from Bacillus cereus.The inhibition of class C beta-lactamases by boronic acids.Interactions between active-site-serine beta-lactamases and mechanism-based inactivators: a kinetic study and an overview.The penicillin-binding site in the exocellular DD-carboxypeptidase-transpeptidase of Actinomadura R39.The acyl-enzyme mechanism of beta-lactamase action. The evidence for class C Beta-lactamases.A retrospective view of beta-lactamases.Trapping the acyl-enzyme intermediate in beta-lactamase I catalysis.Accumulation of acyl-enzyme intermediates during turnover of penicillins by the class A beta-lactamase of Staphylococcus aureus PC1.Evidence for an oxyanion hole in serine beta-lactamases and DD-peptidases.Irreversible inactivation of beta-lactamase I from Bacillus cereus by chlorinated 6-spiroepoxypenicillins.The exocellular beta-lactamase of Streptomyces albus G. Purification, properties and comparison with the exocellular DD-carboxypeptidase.Interactions between non-classical beta-lactam compounds and the beta-lactamases of Actinomadura R39 and Streptomyces albus G.Active sites of beta-lactamases. The chromosomal beta-lactamases of Pseudomonas aeruginosa and Escherichia coli.Amino acid sequence homologies between Escherichia coli penicillin-binding protein 5 and class a β-lactamases
P2860
Q24527332-499A2486-E40C-4798-86E5-1D719534B564Q27658217-399CB62C-7C18-4F42-8C48-CE5A207586E5Q28359796-695F5924-3995-43B0-94A7-1C05D4C22ACCQ28360248-B24EEA15-DA4D-40F6-BC31-89E3D24CD2E5Q28360277-E0AA2218-92C7-499B-B10F-6EDD0BD88250Q28366211-62C575B5-1E50-4681-B48B-CF8133632508Q33962811-FFF59B7C-AF05-4FF0-A660-99D9FAA9C39CQ34274586-1A980471-2676-4EB4-A4AC-CAB7C25B4427Q34300761-523052D0-8E5D-4774-A7C5-A69136C6D36DQ35459274-B30987AC-6F9E-4155-8410-3E3FDFB743EEQ35594207-820EECB0-A93B-49A6-9BFC-1A842893B8C1Q36237266-C5403B76-66EA-4DCA-9420-A47D8CE11681Q36317552-956C3B54-077C-4921-AAD0-CDED6267A381Q37333017-C2BEC683-8726-42FB-809C-396EFE20B14EQ37682870-1206E839-9EF1-4C03-8418-8683F4E4E119Q38334034-83EEE35F-FFF5-49B2-A4A0-9E792971F3C5Q38348221-020A4DF7-109A-4C65-8999-88817C8C5F91Q39568018-8D6EE5C0-6E1F-436A-AA63-DD348C54F717Q39840462-A5CF57DB-E18F-41DE-A7DF-9BFFDA37DC21Q40270998-746C430E-851C-436D-BBFF-F07277175E1AQ41379589-A0B34C59-FC25-4E2E-96BB-33F7C9A90A7CQ41853530-33ECB70E-309D-47AC-A785-D97266CA101DQ41866402-8F3C2306-10AA-4EFE-B0A4-76AFF8C41A11Q41876580-60D4ACB8-5CE6-4446-A1D1-2A59352CEAE6Q41968772-8A412D04-1B19-45F2-BAC0-4A8F1B12C525Q41988440-ACC26947-D16F-465E-A4FC-08B3BED49BFDQ42130830-2DD3C11B-194E-4F4B-922D-175501EC9107Q42161441-F84752F9-623B-49A5-AD4B-FD8041FC3DABQ42804291-B0196908-B62F-4BBB-A120-0639B9D12AC2Q42817920-A8AB76D7-BEB9-4B80-AA24-C038A8C4D84BQ42820512-DD98DF81-CF09-42BF-ADB3-6B0694ACF153Q42861752-9DA42676-D17D-4117-A5DF-26694738AB28Q42882625-B17FDF4B-0A4E-40CC-B24D-FA561CA67DAAQ46596647-DFB73B0C-DB49-4B91-8324-1534B7C24B54Q46601814-8CD3FFEA-5C47-47B1-904B-423C39DD4BD1Q58483907-9F6BD38D-8E99-40EB-93AD-C4507306DFEC
P2860
Penicillinase active sites: labelling of serine-44 in beta-lactamase I by 6beta-bromopenicillanic acid.
description
1979 nî lūn-bûn
@nan
1979年の論文
@ja
1979年論文
@yue
1979年論文
@zh-hant
1979年論文
@zh-hk
1979年論文
@zh-mo
1979年論文
@zh-tw
1979年论文
@wuu
1979年论文
@zh
1979年论文
@zh-cn
name
Penicillinase active sites: la ...... 6beta-bromopenicillanic acid.
@en
type
label
Penicillinase active sites: la ...... 6beta-bromopenicillanic acid.
@en
prefLabel
Penicillinase active sites: la ...... 6beta-bromopenicillanic acid.
@en
P2093
P2860
P1433
P1476
Penicillinase active sites: la ...... 6beta-bromopenicillanic acid.
@en
P2093
Knott-Hunziker V
P2860
P356
10.1016/0014-5793(79)80248-3
P407
P577
1979-03-01T00:00:00Z