Activation of the ATF3 gene through a co-ordinated amino acid-sensing response programme that controls transcriptional regulation of responsive genes following amino acid limitation.
about
Distinct cytoplasmic and nuclear functions of the stress induced protein DDIT3/CHOP/GADD153The p300/CBP-associated factor (PCAF) is a cofactor of ATF4 for amino acid-regulated transcription of CHOPNSAID-activated gene-1 as a molecular target for capsaicin-induced apoptosis through a novel molecular mechanism involving GSK3beta, C/EBPbeta and ATF3.Amino acid availability controls TRB3 transcription in liver through the GCN2/eIF2α/ATF4 pathwayGenomic and proteomic analysis of transcription factor TFII-I reveals insight into the response to cellular stress.Expression profiling after activation of amino acid deprivation response in HepG2 human hepatoma cellsA mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (MEK)-dependent transcriptional program controls activation of the early growth response 1 (EGR1) gene during amino acid limitationAcrolein induces endoplasmic reticulum stress and causes airspace enlargement.Asparagine synthetase: regulation by cell stress and involvement in tumor biologyShort-term cuprizone feeding induces selective amino acid deprivation with concomitant activation of an integrated stress response in oligodendrocytes.Gene expression and integrated stress response in HepG2/C3A cells cultured in amino acid deficient medium.Inhibition of iNOS as a novel effective targeted therapy against triple-negative breast cancer.Dickkopf homolog 1, a Wnt signaling antagonist, is transcriptionally up-regulated via an ATF4-independent and MAPK/ERK-dependent pathway following amino acid deprivationATF2 is required for amino acid-regulated transcription by orchestrating specific histone acetylation.Functional genomic analysis of variation on beef tenderness induced by acute stress in angus cattle.ATF4-dependent regulation of the JMJD3 gene during amino acid deprivation can be rescued in Atf4-deficient cells by inhibition of deacetylation.Translation termination efficiency modulates ATF4 response by regulating ATF4 mRNA translation at 5' short ORFsATF4-dependent transcription mediates signaling of amino acid limitation.Deprivation of protein or amino acid induces C/EBPbeta synthesis and binding to amino acid response elements, but its action is not an absolute requirement for enhanced transcription.Dynamic changes in genomic histone association and modification during activation of the ASNS and ATF3 genes by amino acid limitation.The transcription factor network associated with the amino acid response in mammalian cells.Adaptive changes in amino acid metabolism permit normal longevity in mice consuming a low-carbohydrate ketogenic diet.Activated transcription via mammalian amino acid response elements does not require enhanced recruitment of the Mediator complexRemodeling of lipid metabolism by dietary restriction of essential amino acidsCHOP induces activating transcription factor 5 (ATF5) to trigger apoptosis in response to perturbations in protein homeostasis.Elevated ATF4 expression, in the absence of other signals, is sufficient for transcriptional induction via CCAAT enhancer-binding protein-activating transcription factor response elements.Control of mammalian gene expression by amino acids, especially glutamine.A bifunctional intronic element regulates the expression of the arginine/lysine transporter Cat-1 via mechanisms involving the purine-rich element binding protein A (Pur alpha).Expression and clinical significance of activating transcription factor 3 in human breast cancer.Cellular and animal indispensable amino acid limitation responses and health promotion. Can the two be linked? A critical review.Fibroblast growth factor 21 induction by activating transcription factor 4 is regulated through three amino acid response elements in its promoter region.Cellular responses to individual amino-acid depletion in antibody-expressing and parental CHO cell lines.Identification of a novel amino acid response pathway triggering ATF2 phosphorylation in mammalsDifferential usage of alternate promoters of the human stress response gene ATF3 in stress response and cancer cells.Despite increased ATF4 binding at the C/EBP-ATF composite site following activation of the unfolded protein response, system A transporter 2 (SNAT2) transcription activity is repressed in HepG2 cells.HepG2/C3A cells respond to cysteine deprivation by induction of the amino acid deprivation/integrated stress response pathway.Growing rats respond to a sulfur amino acid-deficient diet by phosphorylation of the alpha subunit of eukaryotic initiation factor 2 heterotrimeric complex and induction of adaptive components of the integrated stress response.Induction of autophagy through the activating transcription factor 4 (ATF4)-dependent amino acid response pathway in maternal skeletal muscle may function as the molecular memory in response to gestational protein restriction to alert offspring to mA delayed antioxidant response in heat-stressed cells expressing a non-DNA binding HSF1 mutant.FGF21 mediates the lipid metabolism response to amino acid starvation.
P2860
Q24312995-07AE2B4B-710D-492D-A9E9-2A851F4548AEQ24678306-BFE24291-B7DF-48AB-B553-88837F4DCE9FQ33759704-FB357B8D-989A-4A12-8E0D-906FE0F64DD4Q33784832-D208B564-E531-4F68-8263-0EF0CFB5BC1EQ33843133-3E29A6D7-2F91-4F8A-9E7E-698A31583E1CQ33847650-317E7D7A-5728-4DAF-BED4-D0ECBCDD2CABQ34107392-7E0A573D-80F1-453F-82D8-3AF87F16F994Q34295437-C6C95D34-2FED-4626-BCA1-BFCB0B24D80CQ34327474-44BC0DD4-C06E-4DB0-A30E-B3B4BFE04300Q34974656-BF7428BE-6803-48A9-9D07-7EBE499CBA6AQ35057755-92467C2D-DB57-4AC5-9CBA-BE2158A56CC9Q35258324-85D8E224-44F2-4E0E-B7C0-6C3183119BA3Q35419038-359210D8-CB5D-430D-A630-DF628ABB3185Q35749733-43829553-8443-47B5-9463-B4C2D2D3E41BQ35903937-231BCE9C-2487-4C2A-88F6-0C0B4CE236A2Q36332920-894D5139-0856-4E0F-AE8F-9D7B043E8F43Q36341562-D1E7A14F-B6E8-431D-AD34-6F37ED39CCBCQ36655003-B9A0FD65-3F9F-4B0A-9EE6-DFAF5B962C92Q36661281-0B015EC7-AAE5-4899-A39A-991A54FCCB3CQ36716443-ACB0B487-A7F8-40D0-9701-1D6C7A1ABA01Q36830376-4D224586-B46A-44C0-83BC-EC4D1F0175BEQ36889022-8EEDBA97-C34A-4212-8FC9-F1E0092529D9Q36909353-D472F574-A7BD-4B6C-B82E-42BC232A8D64Q37031045-91CF4678-3041-4F0E-BAAF-8F3845C2E130Q37056644-6BA4C483-9D09-4682-AA5F-150759F1150CQ37372007-AE9892CE-FB27-47AB-9FA7-1C8783CE64C4Q37403750-9005C9EB-EF43-492B-A967-2AD3253A0297Q37431928-46771276-CD61-4773-8DBE-4D1D7C70173EQ37540417-DEE72A40-9DBC-4D61-994E-A00D8BC0302CQ38056752-1148F6E7-3EAA-4DEE-92A8-14C0A6F7262DQ38783501-A5CB7CA7-F3A6-4B2C-8862-701C323703ACQ39061197-F190135D-FBDB-41DB-B379-F244A5AE7879Q39788329-328AEBA8-738B-4951-9977-687F7138AC2CQ39896710-F99C4BA8-4F48-4ECA-8DB1-D179B51438ACQ39951457-B03E899C-3CB1-4D4C-A94E-707C3865D1ABQ40011352-66DE8616-D562-42F4-A6DB-E0A45738C6F4Q40538991-E0753452-BF08-49DB-AC3D-1F96832C8A78Q40711397-CB63E83B-309A-4132-ABDA-9798D77CC0B7Q42022919-7102AAD1-A460-4F90-818E-172829EF4CADQ42034608-D1280162-25C6-4916-9E32-AAEC222503BE
P2860
Activation of the ATF3 gene through a co-ordinated amino acid-sensing response programme that controls transcriptional regulation of responsive genes following amino acid limitation.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Activation of the ATF3 gene th ...... llowing amino acid limitation.
@en
type
label
Activation of the ATF3 gene th ...... llowing amino acid limitation.
@en
prefLabel
Activation of the ATF3 gene th ...... llowing amino acid limitation.
@en
P2093
P2860
P356
P1433
P1476
Activation of the ATF3 gene th ...... ollowing amino acid limitation
@en
P2093
Michael S Kilberg
Michelle M Thiaville
P2860
P304
P356
10.1042/BJ20061261
P407
P577
2007-01-01T00:00:00Z