Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor cells.
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Cancer as a metabolic diseaseFast kinase domain-containing protein 3 is a mitochondrial protein essential for cellular respirationChChd3, an inner mitochondrial membrane protein, is essential for maintaining crista integrity and mitochondrial functionThe transcriptional co-repressor myeloid translocation gene 16 inhibits glycolysis and stimulates mitochondrial respirationMutations in TTC19 cause mitochondrial complex III deficiency and neurological impairment in humans and fliesHVCN1 modulates BCR signal strength via regulation of BCR-dependent generation of reactive oxygen speciesFission and selective fusion govern mitochondrial segregation and elimination by autophagyCardiolipin and electron transport chain abnormalities in mouse brain tumor mitochondria: lipidomic evidence supporting the Warburg theory of cancerCell Biology Symposium: feed efficiency: mitochondrial function to global gene expressionMitochondrial structure, function and dynamics are temporally controlled by c-MycRole of glucose metabolism and ATP in maintaining PINK1 levels during Parkin-mediated mitochondrial damage responses.Hypoxic regulation of hand1 controls the fetal-neonatal switch in cardiac metabolismTissue- and cell-specific mitochondrial defect in Parkin-deficient miceAutophagy suppresses RIP kinase-dependent necrosis enabling survival to mTOR inhibitionNegative feedback maintenance of heme homeostasis by its receptor, Rev-erbalphaThe Warburg effect: 80 years onCancer stem cell metabolism: a potential target for cancer therapyDrugging the addict: non-oncogene addiction as a target for cancer therapyC13orf31 (FAMIN) is a central regulator of immunometabolic functionA mitochondrial RNAi screen defines cellular bioenergetic determinants and identifies an adenylate kinase as a key regulator of ATP levelsLin28 enhances tissue repair by reprogramming cellular metabolismEnergy failure: does it contribute to neurodegeneration?Culture conditions profoundly impact phenotype in BEAS-2B, a human pulmonary epithelial modelHigh throughput microplate respiratory measurements using minimal quantities of isolated mitochondriaBezielle selectively targets mitochondria of cancer cells to inhibit glycolysis and OXPHOSA chemical screen probing the relationship between mitochondrial content and cell sizeInvestigation of mitochondrial dysfunction by sequential microplate-based respiration measurements from intact and permeabilized neuronsMitochondrial respiration--an important therapeutic target in melanomaNeuroprotective actions of methylene blue and its derivativesInfluence of cell detachment on the respiration rate of tumor and endothelial cellsBerardinelli-seip congenital lipodystrophy 2/seipin is a cell-autonomous regulator of lipolysis essential for adipocyte differentiationDistinct pools of non-glycolytic substrates differentiate brain regions and prime region-specific responses of mitochondriaMetabolic reprogramming for producing energy and reducing power in fumarate hydratase null cells from hereditary leiomyomatosis renal cell carcinomaA H2S-Nampt dependent energetic circuit is critical to survival and cytoprotection from damage in cancer cellsModulation of cell metabolic pathways and oxidative stress signaling contribute to acquired melphalan resistance in multiple myeloma cellsFlexible Sheet-Type Sensor for Noninvasive Measurement of Cellular Oxygen Metabolism on a Culture DishMetformin Antagonizes Cancer Cell Proliferation by Suppressing Mitochondrial-Dependent BiosynthesisMitochondrial Probe Methyltriphenylphosphonium (TPMP) Inhibits the Krebs Cycle Enzyme 2-Oxoglutarate DehydrogenaseMitochondrial phosphatase PTPMT1 is essential for cardiolipin biosynthesisInactivation of the mitochondrial carrier SLC25A25 (ATP-Mg2+/Pi transporter) reduces physical endurance and metabolic efficiency in mice
P2860
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P2860
Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor cells.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Multiparameter metabolic analy ...... pendency in human tumor cells.
@en
type
label
Multiparameter metabolic analy ...... pendency in human tumor cells.
@en
prefLabel
Multiparameter metabolic analy ...... pendency in human tumor cells.
@en
P2093
P1476
Multiparameter metabolic analy ...... pendency in human tumor cells.
@en
P2093
Amy L Swift
Andy Neilson
David A Ferrick
Diane Parslow
James Tamagnine
Jim Orrell
Kristie Lemire
Rebecca Moran
P304
P356
10.1152/AJPCELL.00247.2006
P577
2006-09-13T00:00:00Z