Werner's syndrome: a review of recent research with an analysis of connective tissue metabolism, growth control of cultured cells, and chromosomal aberrations.
about
p53 Modulates the exonuclease activity of Werner syndrome proteinWRN interacts physically and functionally with the recombination mediator protein RAD52Nucleolar localization of the Werner syndrome protein in human cellsAn overexpressed gene transcript in senescent and quiescent human fibroblasts encoding a novel protein in the epidermal growth factor-like repeat family stimulates DNA synthesisMetabolic and Phenotypic Differences between Mice Producing a Werner Syndrome Helicase Mutant Protein and Wrn Null MiceCrystal structure of the HRDC domain of human Werner syndrome protein, WRNEpigenetic inactivation of the premature aging Werner syndrome gene in human cancerMutations in the WRN gene in mice accelerate mortality in a p53-null backgroundThe genesis of atherosclerosis and risk factors: a review.Werner's syndrome with myelofibrosis following diphenylhydantoin therapy after meningiomectomy. An autopsy case.A case of Werner's syndrome associated with osteosarcoma.Effects of mutations in DNA repair genes on formation of ribosomal DNA circles and life span in Saccharomyces cerevisiae.Solution structure of a multifunctional DNA- and protein-binding motif of human Werner syndrome protein.Telomeres and telomerase: basic science implications for aging.Expression profile of Caenorhabditis elegans mutant for the Werner syndrome gene ortholog reveals the impact of vitamin C on development to increase life span.Werner protein protects nonproliferating cells from oxidative DNA damageComparison of proliferation and genomic instability responses to WRN silencing in hematopoietic HL60 and TK6 cells.Werner syndrome as a hereditary risk factor for exocrine pancreatic cancer: potential role of WRN in pancreatic tumorigenesis and patient-tailored therapyTelomeres, chromosome instability and cancerVitamin C restores healthy aging in a mouse model for Werner syndromeRecQ helicases: suppressors of tumorigenesis and premature aging.Werner's syndrome: proliferation in vitro of clones of cells bearing chromosome translocationsChromosome translocations in fibroblast cultures derived from patients with Werner's syndrome.Mutations in the consensus helicase domains of the Werner syndrome gene. Werner's Syndrome Collaborative Group.The cultured diploid fibroblast as a model for the study of cellular aging.Proteome-wide identification of WRN-interacting proteins in untreated and nuclease-treated samples.A novel Werner Syndrome mutation: pharmacological treatment by read-through of nonsense mutations and epigenetic therapiesDown regulation of miR-124 in both Werner syndrome DNA helicase mutant mice and mutant Caenorhabditis elegans wrn-1 reveals the importance of this microRNA in accelerated agingThe gene responsible for Werner syndrome may be a cell division "counting" gene.The role of cellular senescence in Werner syndrome: toward therapeutic intervention in human premature aging.From old organisms to new molecules: integrative biology and therapeutic targets in accelerated human ageing.Werner syndrome protein, WRN, protects cells from DNA damage induced by the benzene metabolite hydroquinoneWerner's syndrome: incidental finding during pregnancy.The Werner Syndrome Helicase Coordinates Sequential Strand Displacement and FEN1-Mediated Flap Cleavage during Polymerase δ Elongation.Different non-synonymous polymorphisms modulate the interaction of the WRN protein to its protein partners and its enzymatic activities.Ascorbate improves metabolic abnormalities in Wrn mutant mice but not the free radical scavenger catechin.Cell division and aging of the organism.Speeding up the clock: The past, present and future of progeria.Hyperinsulinemia and insulin resistance in Wrn null mice fed a diabetogenic diet.Depletion of Werner helicase results in mitotic hyperrecombination and pleiotropic homologous and nonhomologous recombination phenotypes.
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P2860
Werner's syndrome: a review of recent research with an analysis of connective tissue metabolism, growth control of cultured cells, and chromosomal aberrations.
description
1982 nî lūn-bûn
@nan
1982年の論文
@ja
1982年論文
@yue
1982年論文
@zh-hant
1982年論文
@zh-hk
1982年論文
@zh-mo
1982年論文
@zh-tw
1982年论文
@wuu
1982年论文
@zh
1982年论文
@zh-cn
name
Werner's syndrome: a review of ...... , and chromosomal aberrations.
@en
type
label
Werner's syndrome: a review of ...... , and chromosomal aberrations.
@en
prefLabel
Werner's syndrome: a review of ...... , and chromosomal aberrations.
@en
P2860
P356
P1433
P1476
Werner's syndrome: a review of ...... , and chromosomal aberrations.
@en
P2093
P2860
P2888
P356
10.1007/BF00295598
P577
1982-01-01T00:00:00Z
P6179
1020570569