Interferon-inducible expression of APOBEC3 editing enzymes in human hepatocytes and inhibition of hepatitis B virus replication. - Wikidata - awgldk - TriplyDB

Interferon-inducible expression of APOBEC3 editing enzymes in human hepatocytes and inhibition of hepatitis B virus replication.

Interferon-inducible expression of APOBEC3 editing enzymes in human hepatocytes and inhibition of hepatitis B virus replication.

http://www.wikidata.org/entity/Q40275011

about

AID and APOBECs span the gap between innate and adaptive immunity Population stratification of a common APOBEC gene deletion polymorphism APOBEC3 proteins mediate the clearance of foreign DNA from human cells Genetic editing of herpes simplex virus 1 and Epstein-Barr herpesvirus genomes by human APOBEC3 cytidine deaminases in culture and in vivo Sole copy of Z2-type human cytidine deaminase APOBEC3H has inhibitory activity against retrotransposons and HIV-1 Hepatitis B virus replication HIV-1 Vif, APOBEC, and intrinsic immunity Polymorphisms and splice variants influence the antiretroviral activity of human APOBEC3H Associations between activation-induced cytidine deaminase/apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like cytidine deaminase expression, hepatitis B virus (HBV) replication and HBV-associated liver disease (Review)The APOBEC3 family of retroelement restriction factors New pandemics: HIV and AIDS, HCV and chronic hepatitis, influenza virus and flu Molecular mechanisms underlying occult hepatitis B virus infection.APOBEC3G: an intracellular centurion Two regions within the amino-terminal half of APOBEC3G cooperate to determine cytoplasmic localization.APOBEC3B and AID have similar nuclear import mechanisms.The artiodactyl APOBEC3 innate immune repertoire shows evidence for a multi-functional domain organization that existed in the ancestor of placental mammals.Distinct determinants in HIV-1 Vif and human APOBEC3 proteins are required for the suppression of diverse host anti-viral proteins Genetic editing of HBV DNA by monodomain human APOBEC3 cytidine deaminases and the recombinant nature of APOBEC3G.Differences in APOBEC3G expression in CD4+ T helper lymphocyte subtypes modulate HIV-1 infectivity.Self-cytoplasmic DNA upregulates the mutator enzyme APOBEC3A leading to chromosomal DNA damage Massive APOBEC3 editing of hepatitis B viral DNA in cirrhosis.Functions and regulation of the APOBEC family of proteins Different modes of retrovirus restriction by human APOBEC3A and APOBEC3G in vivo.Single- and double-stranded viral RNA generate distinct cytokine and antiviral responses in human fetal membranes.Inhibition of hepatitis B virus replication by MyD88 involves accelerated degradation of pregenomic RNA and nuclear retention of pre-S/S RNAs.Hepatitis C virus infection suppresses the interferon response in the liver of the human hepatocyte chimeric mouse Quantitative profiling of the full APOBEC3 mRNA repertoire in lymphocytes and tissues: implications for HIV-1 restriction APOBEC3A is a specific inhibitor of the early phases of HIV-1 infection in myeloid cells.Innate immune signaling induces high levels of TC-specific deaminase activity in primary monocyte-derived cells through expression of APOBEC3A isoforms Control of hepatitis B virus replication by interferons and Toll-like receptor signaling pathways Evolution of the primate APOBEC3A cytidine deaminase gene and identification of related coding regions.Interferon-alpha induces high expression of APOBEC3G and STAT-1 in vitro and in vivo.Inhibition of alpha interferon (IFN-α)-induced microRNA-122 negatively affects the anti-hepatitis B virus efficiency of IFN-α.Indoleamine 2,3-dioxygenase mediates the antiviral effect of gamma interferon against hepatitis B virus in human hepatocyte-derived cells.DDX3 DEAD-box RNA helicase is a host factor that restricts hepatitis B virus replication at the transcriptional level Somatic hypermutation of human mitochondrial and nuclear DNA by APOBEC3 cytidine deaminases, a pathway for DNA catabolism.Uracil DNA glycosylase counteracts APOBEC3G-induced hypermutation of hepatitis B viral genomes: excision repair of covalently closed circular DNA.Human APOBEC3A isoforms translocate to the nucleus and induce DNA double strand breaks leading to cell stress and death.Type I interferon controls propagation of long interspersed element-1.Deamination-independent inhibition of hepatitis B virus reverse transcription by APOBEC3G.

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P2860

Interferon-inducible expression of APOBEC3 editing enzymes in human hepatocytes and inhibition of hepatitis B virus replication.

http://www.wikidata.org/entity/Q40275011

description

2006 nî lūn-bûn

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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2006年论文

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2006年论文

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Interferon-inducible expressio ...... hepatitis B virus replication.

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Interferon-inducible expressio ...... hepatitis B virus replication.

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Adrian Keogh

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Daniel Candinas

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Deborah Stroka

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François Achermann

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Isabell Greeve

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Jobst Greeve

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Marianne Bonvin

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Simon Wain-Hobson

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6

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43

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Jean-Pierre Vartanian

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7053981

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