A proposal for a novel rationale for critical effect size in dose-response analysis based on a multi-endpoint in vivo study with methyl methanesulfonate.

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An appraisal of critical effect sizes for the benchmark dose approach to assess dose-response relationships in genetic toxicology.Genetic toxicology at the crossroads-from qualitative hazard evaluation to quantitative risk assessment.

P2860

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P2860

A proposal for a novel rationale for critical effect size in dose-response analysis based on a multi-endpoint in vivo study with methyl methanesulfonate.

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2015 nî lūn-bûn

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2015年の論文

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A proposal for a novel rationa ...... with methyl methanesulfonate.

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A proposal for a novel rationa ...... with methyl methanesulfonate.

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A proposal for a novel rationa ...... with methyl methanesulfonate.

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P1476

A proposal for a novel rationa ...... with methyl methanesulfonate.

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Andreas Zeller

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Gonzalo Duran-Pacheco

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Juergen Funk

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Leilei Tang

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Melanie Guérard

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Stephen D Dertinger

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P2860

Methyl methanesulfonate (MMS) produces heat-labile DNA damage but no detectable in vivo DNA double-strand breaks.

Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing

Power failure: why small sample size undermines the reliability of neuroscience

Ethyl methanesulfonate toxicity in Viracept--a comprehensive human risk assessment based on threshold data for genotoxicity.

Statistical model to estimate a threshold dose and its confidence limits for the analysis of sublinear dose-response relationships, exemplified for mutagenicity data.

MGMT: key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents.

A signal-to-noise crossover dose as the point of departure for health risk assessment

Efficient monitoring of in vivo pig-a gene mutation and chromosomal damage: summary of 7 published studies and results from 11 new reference compounds.

Fourth International Workgroup on Genotoxicity testing: results of the in vivo Comet assay workgroup.

MGMT: a personal perspective.

P304

239-253

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P31

scholarly article

P356

10.1093/MUTAGE/GEV077

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P478

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2015-11-20T00:00:00Z

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26590612

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A proposal for a novel rationale for critical effect size in dose-response analysis based on a multi-endpoint in vivo study with methyl methanesulfonate.

about

P2860

P2860

A proposal for a novel rationale for critical effect size in dose-response analysis based on a multi-endpoint in vivo study with methyl methanesulfonate.

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P698