Plasminogen activator inhibitor-1 gene-deficient mice. II. Effects on hemostasis, thrombosis, and thrombolysis.
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Plasminogen activator inhibitor-1 protects endothelial cells from FasL-mediated apoptosisThe plasminogen activator inhibitor-2 gene is not required for normal murine development or survivalSerpins flex their muscle: I. Putting the clamps on proteolysis in diverse biological systemsThe plasminogen activator inhibitor PAI-1 controls in vivo tumor vascularization by interaction with proteases, not vitronectin. Implications for antiangiogenic strategiesGlobal gene expression profiling in PAI-1 knockout murine heart and kidney: molecular basis of cardiac-selective fibrosisA specific plasminogen activator inhibitor-1 antagonist derived from inactivated urokinase.Human complement receptor type 1-directed loading of tissue plasminogen activator on circulating erythrocytes for prophylactic fibrinolysisSelection of peptides that bind to plasminogen activator inhibitor 1 (PAI-1) using random peptide phage-display libraries.Vitronectin is not essential for normal mammalian development and fertility.Hemostasis and alterations of the central nervous systemFactor VII deficiency rescues the intrauterine lethality in mice associated with a tissue factor pathway inhibitor deficit.Platelet protease nexin-1, a serpin that strongly influences fibrinolysis and thrombolysis.Placenta growth factor (PlGF), a novel inducer of plasminogen activator inhibitor-1 (PAI-1) in sickle cell disease (SCD).Plasminogen activator inhibitor-1 is a major stress-regulated gene: implications for stress-induced thrombosis in aged individuals.A slice of PAIPlasminogen activator inhibitor-1 gene-deficient mice. I. Generation by homologous recombination and characterization.Special considerations in the evaluation of the hematology and hemostasis of mutant mice.A novel inhibitor of plasminogen activator inhibitor-1 provides antithrombotic benefits devoid of bleeding effect in nonhuman primates.Peptide-mediated inactivation of recombinant and platelet plasminogen activator inhibitor-1 in vitro.Enhanced venous thrombus resolution in plasminogen activator inhibitor type-2 deficient mice.Allele-specific increase in basal transcription of the plasminogen-activator inhibitor 1 gene is associated with myocardial infarction.Plasminogen activator inhibitor-1 4G/5G polymorphism is associated with coronary artery disease risk: a meta-analysisThe molecular basis for anti-proteolytic and non-proteolytic functions of plasminogen activator inhibitor type-1: roles of the reactive centre loop, the shutter region, the flexible joint region and the small serpin fragment.Thrombin-activatable fibrinolysis inhibitor (TAFI) deficiency is compatible with murine lifeThe NuRD chromatin-remodeling enzyme CHD4 promotes embryonic vascular integrity by transcriptionally regulating extracellular matrix proteolysis.Plasminogen activator inhibitor-type I gene deficient mice show reduced influx of neutrophils in ventilator-induced lung injuryAngiotensin II induces plasminogen activator inhibitor-1 and -2 expression in vascular endothelial and smooth muscle cells.Abrogation of plasminogen activator inhibitor-1-vitronectin interaction ameliorates acute kidney injury in murine endotoxemia.Aging accelerates endotoxin-induced thrombosis : increased responses of plasminogen activator inhibitor-1 and lipopolysaccharide signaling with agingNovel Plasminogen Activator Inhibitor-1 Inhibitors Prevent Diabetic Kidney Injury in a Mouse Model.The plasminogen activator system modulates sympathetic nerve function.Polyoma middle T-induced vascular tumor formation: the role of the plasminogen activator/plasmin system.Long-term antithrombotic protection by in vivo depletion of platelet glycoprotein VI in mice.Essential role of plasminogen activator inhibitor type-1 in radiation enteropathyTissue factor gene expression in the adipose tissues of obese miceObesity and the role of gut and adipose hormones in female reproduction.Molecular evolution of plasminogen activator inhibitor-1 functional stabilityIdentification of tissue-type plasminogen activator-specific plasminogen activator inhibitor-1 mutants. Evidence that second sites of interaction contribute to target specificity.Enhanced clearance of Abeta in brain by sustaining the plasmin proteolysis cascade.The hemostasis system in murine atherosclerosis.
P2860
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P2860
Plasminogen activator inhibitor-1 gene-deficient mice. II. Effects on hemostasis, thrombosis, and thrombolysis.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Plasminogen activator inhibito ...... thrombosis, and thrombolysis.
@en
type
label
Plasminogen activator inhibito ...... thrombosis, and thrombolysis.
@en
prefLabel
Plasminogen activator inhibito ...... thrombosis, and thrombolysis.
@en
P2093
P2860
P356
P1476
Plasminogen activator inhibito ...... thrombosis, and thrombolysis.
@en
P2093
Carmeliet P
Mulligan RC
Schoonjans L
Stassen JM
van den Oord JJ
P2860
P304
P356
10.1172/JCI116893
P407
P577
1993-12-01T00:00:00Z