High-frequency persistence of an impaired allele of the retroviral defense gene TRIM5alpha in humans.
about
Population stratification of a common APOBEC gene deletion polymorphismAdaptive evolution and antiviral activity of the conserved mammalian cytidine deaminase APOBEC3H.All three variable regions of the TRIM5alpha B30.2 domain can contribute to the specificity of retrovirus restrictionImpact of TRIM5α in vivoTRIM5alpha Modulates Immunodeficiency Virus Control in Rhesus MonkeysIntrinsic cellular defenses against human immunodeficiency virusesAn evolutionary screen highlights canonical and noncanonical candidate antiviral genes within the primate TRIM gene familyEvolution of a TRIM5-CypA splice isoform in old world monkeysA rare null allele potentially encoding a dominant-negative TRIM5alpha protein in Baka pygmiesDiscordant evolution of the adjacent antiretroviral genes TRIM22 and TRIM5 in mammals.TRIM5 alpha drives SIVsmm evolution in rhesus macaques.The effect of Trim5 polymorphisms on the clinical course of HIV-1 infection.Interpreting missense mutations in Human TRIM5alpha by computational methodsA large new subset of TRIM genes highly diversified by duplication and positive selection in teleost fish.Polymorphisms in the vitamin A receptor and innate immunity genes influence the antibody response to rubella vaccination.Rubella vaccine-induced cellular immunity: evidence of associations with polymorphisms in the Toll-like, vitamin A and D receptors, and innate immune response genesTRIM5 suppresses cross-species transmission of a primate immunodeficiency virus and selects for emergence of resistant variants in the new speciesGenetic association of the antiviral restriction factor TRIM5alpha with human immunodeficiency virus type 1 infectionInsights into cellular factors that regulate HIV-1 replication in human cellsHow TRIM5alpha defends against retroviral invasionsRestriction of an extinct retrovirus by the human TRIM5alpha antiviral protein.Association study of common genetic variants and HIV-1 acquisition in 6,300 infected cases and 7,200 controls.Role of common human TRIM5alpha variants in HIV-1 disease progressionTRIM5α restriction affects clinical outcome and disease progression in simian immunodeficiency virus-infected rhesus macaquesPersistent resistance to HIV-1 infection in CD4 T cells from exposed uninfected Vietnamese individuals is mediated by entry and post-entry blocks.Modulation of TRIM5alpha activity in human cells by alternatively spliced TRIM5 isoforms.Vaccinomics: current findings, challenges and novel approaches for vaccine developmentBalancing selection and the evolution of functional polymorphism in Old World monkey TRIM5alpha.Vaccinomics and a new paradigm for the development of preventive vaccines against viral infections.In silico analysis of functional single nucleotide polymorphisms in the human TRIM22 geneRole of Human TRIM5α in Intrinsic Immunity.Identification of Owl Monkey CD4 Receptors Broadly Compatible with Early-Stage HIV-1 IsolatesIdentification of an arsenic-sensitive block to primate lentiviral infection of human dendritic cells.Novel TRIM5 isoforms expressed by Macaca nemestrinaAntiretroviral activity of ancestral TRIM5alpha.Associations between polymorphisms in the antiviral TRIM genes and measles vaccine immunity.The control of viral infection by tripartite motif proteins and cyclophilin A.A naturally occurring single amino acid substitution in human TRIM5α linker region affects its anti-HIV type 1 activity and susceptibility to HIV type 1 infection.Special anniversary review: twenty-five years of human immunodeficiency virus research: successes and challenges.Pressure from TRIM5α contributes to control of HIV-1 replication by individuals expressing protective HLA-B alleles.
P2860
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P2860
High-frequency persistence of an impaired allele of the retroviral defense gene TRIM5alpha in humans.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
High-frequency persistence of ...... nse gene TRIM5alpha in humans.
@en
type
label
High-frequency persistence of ...... nse gene TRIM5alpha in humans.
@en
prefLabel
High-frequency persistence of ...... nse gene TRIM5alpha in humans.
@en
P50
P1433
P1476
High-frequency persistence of ...... nse gene TRIM5alpha in humans.
@en
P2093
Joshua M Akey
P304
P356
10.1016/J.CUB.2005.11.045
P407
P577
2006-01-01T00:00:00Z