The tumor suppressor DAP kinase is a target of RSK-mediated survival signaling.
about
Rsk-mediated phosphorylation and 14-3-3ɛ binding of Apaf-1 suppresses cytochrome c-induced apoptosisActivation and function of the MAPKs and their substrates, the MAPK-activated protein kinasesp90 ribosomal S6 kinase: a potential therapeutic target in lung cancerDeath-associated protein kinase: A molecule with functional antagonistic duality and a potential role in inflammatory bowel disease (Review)RSK phosphorylates SOS1 creating 14-3-3-docking sites and negatively regulating MAPK activationProteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometryDAPK-1 binding to a linear peptide motif in MAP1B stimulates autophagy and membrane blebbing.Peptide combinatorial libraries identify TSC2 as a death-associated protein kinase (DAPK) death domain-binding protein and reveal a stimulatory role for DAPK in mTORC1 signaling.Complex formation between S100B protein and the p90 ribosomal S6 kinase (RSK) in malignant melanoma is calcium-dependent and inhibits extracellular signal-regulated kinase (ERK)-mediated phosphorylation of RSKp90 ribosomal S6 kinase 2 promotes invasion and metastasis of human head and neck squamous cell carcinoma cells.Characterization of ERK docking domain inhibitors that induce apoptosis by targeting Rsk-1 and caspase-9.RSK2 mediates NF-{kappa}B activity through the phosphorylation of IkappaBalpha in the TNF-R1 pathway.Ribosomal S6 kinase regulates ischemia-induced progenitor cell proliferation in the adult mouse hippocampus.Quantitative imaging of epithelial cell scattering identifies specific inhibitors of cell motility and cell-cell dissociation.Direct roles of the signaling kinase RSK2 in Cdc25C activation during Xenopus oocyte maturation.ERK/ribosomal S6 kinase (RSK) signaling positively regulates death receptor 5 expression through co-activation of CHOP and Elk1Death-associated protein kinase 1 promotes growth of p53-mutant cancers.Phosphorylation of caspase-8 (Thr-263) by ribosomal S6 kinase 2 (RSK2) mediates caspase-8 ubiquitination and stability.p90RSK2 is essential for FLT3-ITD- but dispensable for BCR-ABL-induced myeloid leukemia.Increased 90-kDa ribosomal S6 kinase (Rsk) activity is protective against mutant huntingtin toxicity.Structural Basis of Ribosomal S6 Kinase 1 (RSK1) Inhibition by S100B Protein: MODULATION OF THE EXTRACELLULAR SIGNAL-REGULATED KINASE (ERK) SIGNALING CASCADE IN A CALCIUM-DEPENDENT WAY.Altered ERK1/2 Signaling in the Brain of Learned Helpless Rats: Relevance in Vulnerability to Developing Stress-Induced Depression.Ran-binding protein 3 phosphorylation links the Ras and PI3-kinase pathways to nucleocytoplasmic transportCritical role for transcription factor C/EBP-beta in regulating the expression of death-associated protein kinase 1.RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation.DANGER is involved in high glucose-induced radioresistance through inhibiting DAPK-mediated anoikis in non-small cell lung cancer.Synthetic lethality screen identifies RPS6KA2 as modifier of epidermal growth factor receptor activity in pancreatic cancer.Modulation of autophagy-like processes by tumor viruses.Pegylated IFN-α suppresses hepatitis C virus by promoting the DAPK-mTOR pathway.Death-associated protein kinase (DAPK) and signal transduction: regulation in cancer.Death-associated protein kinase (DAPK) and signal transduction: additional roles beyond cell death.Targeting tumour-initiating cells to improve the cure rates for triple-negative breast cancer.Targeting RSK2 in human malignancies.Regulation of inflammation by DAPK.Post-translational regulation of the cellular levels of DAPK.Transcription control of DAPK.The DAPK family: a structure-function analysis.The DAP-kinase interactome.Identification of a dominant negative functional domain on DAPK-1 that degrades DAPK-1 protein and stimulates TNFR-1-mediated apoptosis.Human melanoma cells resistant to MAPK inhibitors can be effectively targeted by inhibition of the p90 ribosomal S6 kinase
P2860
Q24301885-6817CF22-0446-428B-9641-7AAC8D9C4391Q24632768-C8BA7439-67B1-42C6-A596-90DA9528188DQ28077322-75F96E76-EB21-49C7-989A-E03B1A14966BQ28083490-B9C917C6-EF3B-475F-ABBA-9894C84AB9F7Q28271724-1C40AB97-9DA6-4272-8B70-3E09F167A64EQ28280900-8564C689-3D54-4F90-AC13-1C23EAA63104Q33314701-727DB88F-72B4-4B10-98D5-166DE667C0B2Q33381467-47745054-AE0A-488A-865F-03864456E9EEQ33556286-1AC091FE-4EF9-4441-84DF-C3739FE2A50DQ33755364-2083ED54-D387-4A6F-9B3E-5B9C36DB0F07Q33789572-19D63D59-D95E-470A-ACD5-88FD649538ACQ34072205-CFC490F3-E73E-45FE-A321-91F1ACAD4686Q34138270-B1FC0377-86E8-4853-B49A-FB16755A8760Q34327047-6678D72F-DDF7-483D-9D30-F066ED6637B4Q34359234-3FFD6E69-6749-4DFA-B6C7-5B06D1B3CFA1Q34438717-5809BC48-3359-4A2C-8642-F52D9C51B198Q34480753-13670739-667B-45C3-839E-22A46DBA42B2Q34606074-8D640222-CBFD-4746-964B-53D64396B8DCQ35083267-9C855129-B4A1-4C2D-9F0D-611E36233651Q35552239-B2089ADA-876B-4F50-97D0-1D7ABA5D5923Q36419214-E9C967EC-A795-4230-AE38-96219E203398Q36453879-0C462438-8769-4A52-9965-19A31713403BQ36493867-49AC4814-8BE4-4725-9C19-D51C39130FC1Q36540282-C8F88089-4A1A-46DE-B2EB-866AAF2A0585Q36745240-48E31875-F0F3-4675-86A8-E08EFFBE07E2Q36916437-8170A165-05C0-4993-9F05-1FC3C729ACBFQ37448070-A5B0873B-04FD-4D63-9985-CB16071B7D44Q37512255-4258E391-570D-4268-B214-49D3184F99EDQ37534152-25C7B546-96D8-4B7D-BE10-DD0B30E4B439Q37624861-FD402649-5784-4AF1-864B-3BE16D64D82DQ37624869-ADCD8DC3-ABC2-4BAD-8419-CD8D38E9B3AFQ37775105-01FE862C-F410-42B1-A680-2811DC000FB4Q37802388-6ACB8249-3475-4733-89F4-3A71E21A5FFCQ38159467-A8B92BD5-177F-41D9-8437-F2DF17D628A9Q38159469-3872DC05-F37E-43E9-8BE8-3F2187C5BF97Q38161832-AFEA0175-047E-457D-8511-BF8145815FF2Q38162088-CD634F82-89C1-48D0-859B-3AE9399486C7Q38162089-FD6FC96C-DB81-467D-9CA3-2E89F07C4E7AQ38304316-B3963CCC-366B-47C9-A23B-BEC5DDBB646BQ38834031-826019A7-9B2A-439B-A824-D3A007787EE9
P2860
The tumor suppressor DAP kinase is a target of RSK-mediated survival signaling.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
The tumor suppressor DAP kinase is a target of RSK-mediated survival signaling.
@en
type
label
The tumor suppressor DAP kinase is a target of RSK-mediated survival signaling.
@en
prefLabel
The tumor suppressor DAP kinase is a target of RSK-mediated survival signaling.
@en
P2093
P1433
P1476
The tumor suppressor DAP kinase is a target of RSK-mediated survival signaling.
@en
P2093
Bryan A Ballif
John Blenis
Rana Anjum
P304
P356
10.1016/J.CUB.2005.08.050
P407
P577
2005-10-01T00:00:00Z