RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation. - Wikidata - awgldk - TriplyDB

RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation.

RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation.

http://www.wikidata.org/entity/Q36745240

about

PHLPP-mediated dephosphorylation of S6K1 inhibits protein translation and cell growth Substrate preference and phosphatidylinositol monophosphate inhibition of the catalytic domain of the Per-Arnt-Sim domain kinase PASKIN Deregulation of the PI3K and KRAS signaling pathways in human cancer cells determines their response to everolimus The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation FGF19 as a postprandial, insulin-independent activator of hepatic protein and glycogen synthesis Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases Skeletal muscle protein balance in mTOR heterozygous mice in response to inflammation and leucine Ribosomal Protein S6 Phosphorylation in the Nervous System: From Regulation to Function Myelin management by the 18.5-kDa and 21.5-kDa classic myelin basic protein isoforms Spatiotemporal characterization of mTOR kinase activity following kainic acid induced status epilepticus and analysis of rat brain response to chronic rapamycin treatment MYC cooperates with AKT in prostate tumorigenesis and alters sensitivity to mTOR inhibitors TORC1 and TORC2 work together to regulate ribosomal protein S6 phosphorylation in Saccharomyces cerevisiae.Dopamine receptors - IUPHAR Review 13 Nutritional and contractile regulation of human skeletal muscle protein synthesis and mTORC1 signaling Antitumor activity of rapamycin in a Phase I trial for patients with recurrent PTEN-deficient glioblastoma Mice deficient in ribosomal protein S6 phosphorylation suffer from muscle weakness that reflects a growth defect and energy deficit Striatal cholinergic interneurons display activity-related phosphorylation of ribosomal protein S6 Vigabatrin inhibits seizures and mTOR pathway activation in a mouse model of tuberous sclerosis complex Distinct patterns of DNA damage response and apoptosis correlate with Jak/Stat and PI3kinase response profiles in human acute myelogenous leukemia Caveolin-1 promotes Ewing sarcoma metastasis regulating MMP-9 expression through MAPK/ERK pathway In Vivo Phosphoproteomics Analysis Reveals the Cardiac Targets of -Adrenergic Receptor Signaling Development of a RSK Inhibitor as a Novel Therapy for Triple-Negative Breast Cancer.Molecular mechanisms for mitochondrial adaptation to exercise training in skeletal muscle.PI3K/AKT pathway mutations cause a spectrum of brain malformations from megalencephaly to focal cortical dysplasia Cellular reprogramming through mitogen-activated protein kinases.Phosphorylation of eukaryotic translation initiation factor 4B (EIF4B) by open reading frame 45/p90 ribosomal S6 kinase (ORF45/RSK) signaling axis facilitates protein translation during Kaposi sarcoma-associated herpesvirus (KSHV) lytic replication Immunoglobulin E induces VEGF production in mast cells and potentiates their pro-tumorigenic actions through a Fyn kinase-dependent mechanism.Parallel measurement of dynamic changes in translation rates in single cells.A circuitry and biochemical basis for tuberous sclerosis symptoms: from epilepsy to neurocognitive deficits Regulation of the cardiomyocyte transcriptome vs translatome by endothelin-1 and insulin: translational regulation of 5' terminal oligopyrimidine tract (TOP) mRNAs by insulin.Distinct changes in cAMP and extracellular signal-regulated protein kinase signalling in L-DOPA-induced dyskinesia.Analysis of receptor tyrosine kinases (RTKs) and downstream pathways in chordomas Local translation in primary afferent fibers regulates nociception Peptide combinatorial libraries identify TSC2 as a death-associated protein kinase (DAPK) death domain-binding protein and reveal a stimulatory role for DAPK in mTORC1 signaling.c-Fos overexpression increases the proliferation of human hepatocytes by stabilizing nuclear Cyclin D1 Flow-cytometric phosphoprotein analysis reveals agonist and temporal differences in responses of murine hematopoietic stem/progenitor cells Differential regulation of type I interferon and epidermal growth factor pathways by a human Respirovirus virulence factor.A high-throughput, cell-based screening method for siRNA and small molecule inhibitors of mTORC1 signaling using the In Cell Western technique The translation regulatory subunit eIF3f controls the kinase-dependent mTOR signaling required for muscle differentiation and hypertrophy in mouse.Tsc/mTORC1 signaling in oocytes governs the quiescence and activation of primordial follicles

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P2860

RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation.

http://www.wikidata.org/entity/Q36745240

description

2007 nî lūn-bûn

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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2007年论文

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name

RAS/ERK signaling promotes sit ...... tes cap-dependent translation.

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RAS/ERK signaling promotes sit ...... tes cap-dependent translation.

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type

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RAS/ERK signaling promotes sit ...... tes cap-dependent translation.

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RAS/ERK signaling promotes sit ...... tes cap-dependent translation.

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RAS/ERK signaling promotes sit ...... tes cap-dependent translation.

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RAS/ERK signaling promotes sit ...... tes cap-dependent translation.

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P1433

Journal of Biological Chemistry

P1476

RAS/ERK signaling promotes sit ...... tes cap-dependent translation.

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P2093

David Shahbazian

http://www.w3.org/2001/XMLSchema#string

Hieu Vu

http://www.w3.org/2001/XMLSchema#string

Jack Taunton

http://www.w3.org/2001/XMLSchema#string

John Blenis

http://www.w3.org/2001/XMLSchema#string

Marina K Holz

http://www.w3.org/2001/XMLSchema#string

Michael S Cohen

http://www.w3.org/2001/XMLSchema#string

P2860

The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity

Involvement of proteasome alpha-subunit PSMA7 in hepatitis C virus internal ribosome entry site-mediated translation.

Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase

S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway

Phosphorylation of p90 ribosomal S6 kinase (RSK) regulates extracellular signal-regulated kinase docking and RSK activity

Characterization of S6K2, a novel kinase homologous to S6K1

Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases

Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis

Upstream and downstream of mTOR

Kinetic determination of the effects of ADP-ribosylation on the interaction of eukaryotic elongation factor 2 with ribosomes

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14056-14064

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scholarly article

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10.1074/JBC.M700906200

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19

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282

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Philippe P. Roux

Nahum Sonenberg

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2007-03-14T00:00:00Z

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17360704

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phosphorylation

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3618456

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