Expression of cytochromes P450, conjugating enzymes and nuclear receptors in human hepatoma HepaRG cells.
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Experimental models of hepatotoxicity related to acute liver failureStem cell differentiation and human liver diseaseRNA-Seq profiling reveals novel hepatic gene expression pattern in aflatoxin B1 treated ratsProduction of Infectious Hepatitis C Virus by Well-Differentiated, Growth-Arrested Human Hepatoma-Derived CellsA cellular model to study drug-induced liver injury in nonalcoholic fatty liver disease: Application to acetaminophenComparative gene expression profiles induced by PPARγ and PPARα/γ agonists in human hepatocytesLiver progenitor cell line HepaRG differentiated in a bioartificial liver effectively supplies liver support to rats with acute liver failureComparison of human hepatoma HepaRG cells with human and rat hepatocytes in uptake transport assays in order to predict a risk of drug induced hepatotoxicityApplication of the TGx-28.65 transcriptomic biomarker to classify genotoxic and non-genotoxic chemicals in human TK6 cells in the presence of rat liver S9Research Advances on Hepatotoxicity of Herbal Medicines in ChinaFluorometric evaluation of CYP3A4 expression using improved transgenic HepaRG cells carrying a dual-colour reporter for CYP3A4 and CYP3A7.A comparison of whole genome gene expression profiles of HepaRG cells and HepG2 cells to primary human hepatocytes and human liver tissues.Upregulation of CYP 450s expression of immortalized hepatocyte-like cells derived from mesenchymal stem cells by enzyme inducers.Mouse liver repopulation with hepatocytes generated from human fibroblasts.Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010.Gene Expression Changes Induced by PPAR Gamma Agonists in Animal and Human Liver.Inflammatory cytokines promote the retrodifferentiation of tumor-derived hepatocyte-like cells to progenitor cells.Zebrafish as model organisms for studying drug-induced liver injurySimilarities and differences in the expression of drug-metabolizing enzymes between human hepatic cell lines and primary human hepatocytes.HepaRG cells: a human model to study mechanisms of acetaminophen hepatotoxicityFrom whole body to cellular models of hepatic triglyceride metabolism: man has got to know his limitationsDNA adduct formation of 4-aminobiphenyl and heterocyclic aromatic amines in human hepatocytes.Suppression of CYP2C9 by microRNA hsa-miR-128-3p in human liver cells and association with hepatocellular carcinoma.Transient gene delivery for functional enrichment of differentiating embryonic stem cells.Characterization of primary human hepatocytes, HepG2 cells, and HepaRG cells at the mRNA level and CYP activity in response to inducers and their predictivity for the detection of human hepatotoxins.In Vitro Model for Hepatotoxicity Studies Based on Primary Human Hepatocyte Cultivation in a Perfused 3D Bioreactor System.Comparative Proteomic Characterization of 4 Human Liver-Derived Single Cell Culture Models Reveals Significant Variation in the Capacity for Drug Disposition, Bioactivation, and Detoxication.Genome-wide analysis of human constitutive androstane receptor (CAR) transcriptome in wild-type and CAR-knockout HepaRG cellsCombination treatment with 6-mercaptopurine and allopurinol in HepG2 and HEK293 cells - Effects on gene expression levels and thiopurine metabolism.Acetaminophen cytotoxicity is ameliorated in a human liver organotypic co-culture modelIn vitro models for liver toxicity testing.In vitro-in vivo extrapolation of hepatic clearance: biological tools, scaling factors, model assumptions and correct concentrations.Induction of hepatic cytochrome P450 enzymes: methods, mechanisms, recommendations, and in vitro-in vivo correlations.Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.Optimization, formulation, and characterization of multiflavonoids-loaded flavanosome by bulk or sequential techniqueCurrent industrial practices in assessing CYP450 enzyme induction: preclinical and clinicalStudies on the role of metabolic activation in tyrosine kinase inhibitor-dependent hepatotoxicity: induction of CYP3A4 enhances the cytotoxicity of lapatinib in HepaRG cellsComparison of Liver Cell Models Using the Basel Phenotyping Cocktail.The human hepatic cell line HepaRG as a possible cell source for the generation of humanized liver TK-NOG mice.Induction of expression of aryl hydrocarbon receptor-dependent genes in human HepaRG cell line modified by shRNA and treated with β-naphthoflavone
P2860
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P2860
Expression of cytochromes P450, conjugating enzymes and nuclear receptors in human hepatoma HepaRG cells.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Expression of cytochromes P450 ...... n human hepatoma HepaRG cells.
@en
type
label
Expression of cytochromes P450 ...... n human hepatoma HepaRG cells.
@en
prefLabel
Expression of cytochromes P450 ...... n human hepatoma HepaRG cells.
@en
P2093
P356
P1476
Expression of cytochromes P450 ...... n human hepatoma HepaRG cells.
@en
P2093
André Guillouzo
Caroline Aninat
Christiane Guguen-Guillouzo
Denise Glaise
Fabrice Morel
Sophie Langouët
Typhen Le Charpentier
P356
10.1124/DMD.105.006759
P50
P577
2005-10-04T00:00:00Z