Histone acetylation-independent effect of histone deacetylase inhibitors on Akt through the reshuffling of protein phosphatase 1 complexes.
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Histone deacetylase 6 interacts with the microtubule-associated protein tauTargeting protein serine/threonine phosphatases for drug developmentPost-translational regulation of the Drosophila circadian clock requires protein phosphatase 1 (PP1)Histone deacetylase 6 plays a role as a distinct regulator of diverse cellular processesHDACs, histone deacetylation and gene transcription: from molecular biology to cancer therapeuticsHDAC4 mediates development of hypertension via vascular inflammation in spontaneous hypertensive rats.Androgen receptor phosphorylation and activity are regulated by an association with protein phosphatase 1Inhibitory effect of HGF on invasiveness of aggressive MDA-MB231 breast carcinoma cells, and role of HDACs.Preclinical validation of AR42, a novel histone deacetylase inhibitor, as treatment for vestibular schwannomas.AR42, a novel histone deacetylase inhibitor, as a potential therapy for vestibular schwannomas and meningiomas.Lymphocyte chemotaxis is regulated by histone deacetylase 6, independently of its deacetylase activity.Histone deacetylase classes I and II regulate Kaposi's sarcoma-associated herpesvirus reactivation.HMBA releases P-TEFb from HEXIM1 and 7SK snRNA via PI3K/Akt and activates HIV transcription.Ribosome-inactivating proteins isolated from dietary bitter melon induce apoptosis and inhibit histone deacetylase-1 selectively in premalignant and malignant prostate cancer cells.Targeting HSP90-HDAC6 Regulating Network Implicates Precision Treatment of Breast Cancer.Histone deacetylase inhibitors: a chemical genetics approach to understanding cellular functions.The clinical development of histone deacetylase inhibitors as targeted anticancer drugs.Administration of a Histone Deacetylase Inhibitor into the Basolateral Amygdala Enhances Memory Consolidation, Delays Extinction, and Increases Hippocampal BDNF Levels.Paxillin inhibits HDAC6 to regulate microtubule acetylation, Golgi structure, and polarized migration.Ferritin H induction by histone deacetylase inhibitors.HDAC inhibition attenuates inflammatory, hypertrophic, and hypertensive responses in spontaneously hypertensive rats.Current limitations and future opportunities for epigenetic therapies.Anticolon cancer activity of largazole, a marine-derived tunable histone deacetylase inhibitor.Histone deacetylase inhibitors stimulate histone H3 lysine 4 methylation in part via transcriptional repression of histone H3 lysine 4 demethylases.Pan-histone deacetylase inhibitors regulate signaling pathways involved in proliferative and pro-inflammatory mechanisms in H9c2 cellsC6-ceramide synergistically potentiates the anti-tumor effects of histone deacetylase inhibitors via AKT dephosphorylation and α-tubulin hyperacetylation both in vitro and in vivo.Small molecule inhibitors in acute myeloid leukemia: from the bench to the clinicEfficacy of histone deacetylase and estrogen receptor inhibition in breast cancer cells due to concerted down regulation of AktHDAC-inhibitor (S)-8 disrupts HDAC6-PP1 complex prompting A375 melanoma cell growth arrest and apoptosis.Trichostatin A modulates thiazolidinedione-mediated suppression of tumor necrosis factor α-induced lipolysis in 3T3-L1 adipocytesThe HDAC inhibitor LBH589 induces ERK-dependent prometaphase arrest in prostate cancer via HDAC6 inactivation and down-regulationMorphoproteomics identifies constitutive activation of the mTORC2/Akt and NF-κB pathways and expressions of IGF-1R, Sirt1, COX-2, and FASN in peripheral T-cell lymphomas: pathogenetic implications and therapeutic options.Inhibition of SIRT2 in merlin/NF2-mutant Schwann cells triggers necrosis.mTORC1/C2 and pan-HDAC inhibitors synergistically impair breast cancer growth by convergent AKT and polysome inhibiting mechanisms.Role of glycogen synthase kinase 3 beta (GSK3beta) in mediating the cytotoxic effects of the histone deacetylase inhibitor trichostatin A (TSA) in MCF-7 breast cancer cellsPhosphatidylinositol 3-kinase/protein kinase Czeta-induced phosphorylation of Sp1 and p107 repressor release have a critical role in histone deacetylase inhibitor-mediated derepression [corrected] of transcription of the luteinizing hormone receptorRegulation of endothelial cell proliferation and vascular assembly through distinct mTORC2 signaling pathways.Antitumor activity of SAHA, a novel histone deacetylase inhibitor, against murine B cell lymphoma A20 cells in vitro and in vivo.Valproic acid and butyrate induce apoptosis in human cancer cells through inhibition of gene expression of Akt/protein kinase BNovel oral histone deacetylase inhibitor, MPT0E028, displays potent growth-inhibitory activity against human B-cell lymphoma in vitro and in vivo.
P2860
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P2860
Histone acetylation-independent effect of histone deacetylase inhibitors on Akt through the reshuffling of protein phosphatase 1 complexes.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Histone acetylation-independen ...... otein phosphatase 1 complexes.
@en
type
label
Histone acetylation-independen ...... otein phosphatase 1 complexes.
@en
prefLabel
Histone acetylation-independen ...... otein phosphatase 1 complexes.
@en
P2093
P2860
P356
P1476
Histone acetylation-independen ...... otein phosphatase 1 complexes.
@en
P2093
Chang-Shi Chen
Ching-Shih Chen
Ping-Hui Tseng
Shu-Chuan Weng
P2860
P304
38879-38887
P356
10.1074/JBC.M505733200
P407
P577
2005-09-26T00:00:00Z