Malaria-infected mice are completely cured by one 6 mg/kg oral dose of a new monomeric trioxane sulfide combined with mefloquine.
about
Recent advances in malaria drug discoveryModelling the time course of antimalarial parasite killing: a tour of animal and human models, translation and challengesA furoxan-amodiaquine hybrid as a potential therapeutic for three parasitic diseases().New insight-guided approaches to detect, cure, prevent and eliminate malaria.Antimalarial chemotherapy: artemisinin-derived dimer carbonates and thiocarbonates.Malaria-infected mice live until at least day 30 after a new artemisinin-derived thioacetal thiocarbonate combined with mefloquine are administered together in a single, low, oral dose.The survival times of malaria-infected mice are prolonged more by several new two-carbon-linked artemisinin-derived dimer carbamates than by the trioxane antimalarial drug artemether.Microbial Flavoprotein Monooxygenases as Mimics of Mammalian Flavin-Containing Monooxygenases for the Enantioselective Preparation of Drug Metabolites.
P2860
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P2860
Malaria-infected mice are completely cured by one 6 mg/kg oral dose of a new monomeric trioxane sulfide combined with mefloquine.
description
2011 nî lūn-bûn
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2011年の論文
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2011年論文
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2011年論文
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name
Malaria-infected mice are comp ...... fide combined with mefloquine.
@en
type
label
Malaria-infected mice are comp ...... fide combined with mefloquine.
@en
prefLabel
Malaria-infected mice are comp ...... fide combined with mefloquine.
@en
P2093
P2860
P356
P1476
Malaria-infected mice are comp ...... fide combined with mefloquine.
@en
P2093
Abhai Tripathi
David Sullivan
Elizabeth Nenortas
Gary H Posner
Lauren E Woodard
Rachel D Slack
Sonya C T Girdwood
Theresa A Shapiro
P2860
P304
P356
10.1021/JM201214D
P407
P50
P577
2011-12-15T00:00:00Z