Sustained localized expression of ligand for the activating NKG2D receptor impairs natural cytotoxicity in vivo and reduces tumor immunosurveillance. - Wikidata - awgldk - TriplyDB

Sustained localized expression of ligand for the activating NKG2D receptor impairs natural cytotoxicity in vivo and reduces tumor immunosurveillance.

Sustained localized expression of ligand for the activating NKG2D receptor impairs natural cytotoxicity in vivo and reduces tumor immunosurveillance.

http://www.wikidata.org/entity/Q40382191

about

Human NKG2D-ligands: cell biology strategies to ensure immune recognition Natural killer cell cytotoxicity is suppressed by exposure to the human NKG2D ligand MICA*008 that is shed by tumor cells in exosomes A novel strategy for evasion of NK cell immunity by tumours expressing core2 O-glycans Immune recruitment and therapeutic synergy: keys to optimizing oncolytic viral therapy?Activation receptor-induced tolerance of mature NK cells in vivo requires signaling through the receptor and is reversible Regulation of immune cell function and differentiation by the NKG2D receptor Resistance to cytarabine induces the up-regulation of NKG2D ligands and enhances natural killer cell lysis of leukemic cells Targeting microRNAs as key modulators of tumor immune response Newtonian cell interactions shape natural killer cell education Duality of the immune response in cancer: lessons learned from skin Natural killer cell tolerance: control by self or self-control?Current perspectives on natural killer cell education and tolerance: emerging roles for inhibitory receptors NKG2D Ligands in Tumor Immunity: Two Sides of a Coin Transfer of NKG2D and MICB at the cytotoxic NK cell immune synapse correlates with a reduction in NK cell cytotoxic function.The traffic of the NKG2D/Dap10 receptor complex during natural killer (NK) cell activation Perturbation of NK cell peripheral homeostasis accelerates prostate carcinoma metastasis.Cellular expression, trafficking, and function of two isoforms of human ULBP5/RAET1G.Dendritic cell-derived exosomes promote natural killer cell activation and proliferation: a role for NKG2D ligands and IL-15Ralpha.Human IgG1 antibodies antagonizing activating receptor NKG2D on natural killer cells Blockade of immunosuppressive cytokines restores NK cell antiviral function in chronic hepatitis B virus infection Systems biology approaches to understanding Epithelial Mesenchymal Transition (EMT) in mucosal remodeling and signaling in asthma Intact NKG2D-independent function of NK cells chronically stimulated with the NKG2D ligand Rae-1 Transcription of the activating receptor NKG2D in natural killer cells is regulated by STAT3 tyrosine phosphorylation.IL-23 suppresses innate immune response independently of IL-17A during carcinogenesis and metastasis.Adaptations of Natural Killer Cells to Self-MHC Class I.Human tumour immune evasion via TGF-β blocks NK cell activation but not survival allowing therapeutic restoration of anti-tumour activity.Human ovarian tumor cells escape γδ T cell recognition partly by down regulating surface expression of MICA and limiting cell cycle related molecules.Tuning of natural killer cell reactivity by NKp46 and Helios calibrates T cell responses.HIV-1 Vpr up-regulates expression of ligands for the activating NKG2D receptor and promotes NK cell-mediated killing.Mechanisms of NK cell-macrophage Bacillus anthracis crosstalk: a balance between stimulation by spores and differential disruption by toxins.Human Herpesvirus 8 (HHV8) sequentially shapes the NK cell repertoire during the course of asymptomatic infection and Kaposi sarcoma Interleukin 10 decreases MICA expression on melanoma cell surface.Immune evasion mediated by tumor-derived lactate dehydrogenase induction of NKG2D ligands on myeloid cells in glioblastoma patients.Re-educating natural killer cells.Skin immune sentinels in health and disease.Regulation of ligands for the NKG2D activating receptor.Gene expression profiling elucidates a specific role for RARgamma in the retinoic acid-induced differentiation of F9 teratocarcinoma stem cells Ovarian tumor-associated microRNA-20a decreases natural killer cell cytotoxicity by downregulating MICA/B expression.Synovial tissue-infiltrating natural killer cells in osteoarthritis and periprosthetic inflammation.Mature natural killer cells with phenotypic and functional alterations accumulate upon sustained stimulation with IL-15/IL-15Ralpha complexes.

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P2860

Sustained localized expression of ligand for the activating NKG2D receptor impairs natural cytotoxicity in vivo and reduces tumor immunosurveillance.

http://www.wikidata.org/entity/Q40382191

description

2005 nî lūn-bûn

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2005年論文

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2005年論文

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2005年论文

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2005年论文

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2005年论文

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name

Sustained localized expression ...... uces tumor immunosurveillance.

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Sustained localized expression ...... uces tumor immunosurveillance.

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Sustained localized expression ...... uces tumor immunosurveillance.

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Nature Immunology

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Sustained localized expression ...... uces tumor immunosurveillance.

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P2093

David E Oppenheim

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Julie M Lewis

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Michael Girardi

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Renata Filler

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Robert E Tigelaar

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Sarah L Clarke

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Scott J Roberts

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P2860

Broad tumor-associated expression and recognition by tumor-derived gamma delta T cells of MICA and MICB

Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA

Costimulation of CD8alphabeta T cells by NKG2D via engagement by MIC induced on virus-infected cells

ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor

Binding of Escherichia coli adhesin AfaE to CD55 triggers cell-surface expression of the MHC class I-related molecule MICA

Assembly and function of the two ABC transporter proteins encoded in the human major histocompatibility complex

Transforming growth factor beta 1 inhibits expression of NKp30 and NKG2D receptors: consequences for the NK-mediated killing of dendritic cells

Innate immune recognition

Efficient selection for high-expression transfectants with a novel eukaryotic vector

Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

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928-937

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9

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6

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Adrian Clive Hayday

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2005-08-14T00:00:00Z

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7645228

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1008564303

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16116470

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