Sustained localized expression of ligand for the activating NKG2D receptor impairs natural cytotoxicity in vivo and reduces tumor immunosurveillance.
about
Human NKG2D-ligands: cell biology strategies to ensure immune recognitionNatural killer cell cytotoxicity is suppressed by exposure to the human NKG2D ligand MICA*008 that is shed by tumor cells in exosomesA novel strategy for evasion of NK cell immunity by tumours expressing core2 O-glycansImmune recruitment and therapeutic synergy: keys to optimizing oncolytic viral therapy?Activation receptor-induced tolerance of mature NK cells in vivo requires signaling through the receptor and is reversibleRegulation of immune cell function and differentiation by the NKG2D receptorResistance to cytarabine induces the up-regulation of NKG2D ligands and enhances natural killer cell lysis of leukemic cellsTargeting microRNAs as key modulators of tumor immune responseNewtonian cell interactions shape natural killer cell educationDuality of the immune response in cancer: lessons learned from skinNatural killer cell tolerance: control by self or self-control?Current perspectives on natural killer cell education and tolerance: emerging roles for inhibitory receptorsNKG2D Ligands in Tumor Immunity: Two Sides of a CoinTransfer of NKG2D and MICB at the cytotoxic NK cell immune synapse correlates with a reduction in NK cell cytotoxic function.The traffic of the NKG2D/Dap10 receptor complex during natural killer (NK) cell activationPerturbation of NK cell peripheral homeostasis accelerates prostate carcinoma metastasis.Cellular expression, trafficking, and function of two isoforms of human ULBP5/RAET1G.Dendritic cell-derived exosomes promote natural killer cell activation and proliferation: a role for NKG2D ligands and IL-15Ralpha.Human IgG1 antibodies antagonizing activating receptor NKG2D on natural killer cellsBlockade of immunosuppressive cytokines restores NK cell antiviral function in chronic hepatitis B virus infectionSystems biology approaches to understanding Epithelial Mesenchymal Transition (EMT) in mucosal remodeling and signaling in asthmaIntact NKG2D-independent function of NK cells chronically stimulated with the NKG2D ligand Rae-1Transcription of the activating receptor NKG2D in natural killer cells is regulated by STAT3 tyrosine phosphorylation.IL-23 suppresses innate immune response independently of IL-17A during carcinogenesis and metastasis.Adaptations of Natural Killer Cells to Self-MHC Class I.Human tumour immune evasion via TGF-β blocks NK cell activation but not survival allowing therapeutic restoration of anti-tumour activity.Human ovarian tumor cells escape γδ T cell recognition partly by down regulating surface expression of MICA and limiting cell cycle related molecules.Tuning of natural killer cell reactivity by NKp46 and Helios calibrates T cell responses.HIV-1 Vpr up-regulates expression of ligands for the activating NKG2D receptor and promotes NK cell-mediated killing.Mechanisms of NK cell-macrophage Bacillus anthracis crosstalk: a balance between stimulation by spores and differential disruption by toxins.Human Herpesvirus 8 (HHV8) sequentially shapes the NK cell repertoire during the course of asymptomatic infection and Kaposi sarcomaInterleukin 10 decreases MICA expression on melanoma cell surface.Immune evasion mediated by tumor-derived lactate dehydrogenase induction of NKG2D ligands on myeloid cells in glioblastoma patients.Re-educating natural killer cells.Skin immune sentinels in health and disease.Regulation of ligands for the NKG2D activating receptor.Gene expression profiling elucidates a specific role for RARgamma in the retinoic acid-induced differentiation of F9 teratocarcinoma stem cellsOvarian tumor-associated microRNA-20a decreases natural killer cell cytotoxicity by downregulating MICA/B expression.Synovial tissue-infiltrating natural killer cells in osteoarthritis and periprosthetic inflammation.Mature natural killer cells with phenotypic and functional alterations accumulate upon sustained stimulation with IL-15/IL-15Ralpha complexes.
P2860
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P2860
Sustained localized expression of ligand for the activating NKG2D receptor impairs natural cytotoxicity in vivo and reduces tumor immunosurveillance.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Sustained localized expression ...... uces tumor immunosurveillance.
@en
type
label
Sustained localized expression ...... uces tumor immunosurveillance.
@en
prefLabel
Sustained localized expression ...... uces tumor immunosurveillance.
@en
P2093
P2860
P356
P1433
P1476
Sustained localized expression ...... uces tumor immunosurveillance.
@en
P2093
David E Oppenheim
Julie M Lewis
Michael Girardi
Renata Filler
Robert E Tigelaar
Sarah L Clarke
Scott J Roberts
P2860
P2888
P304
P356
10.1038/NI1239
P407
P577
2005-08-14T00:00:00Z
P5875
P6179
1008564303