Development of infectious clones for virulent and avirulent pichinde viruses: a model virus to study arenavirus-induced hemorrhagic fevers.
about
Arenavirus reverse genetics: new approaches for the investigation of arenavirus biology and development of antiviral strategiesUncovering viral protein-protein interactions and their role in arenavirus life cycleReporter-Expressing, Replicating-Competent Recombinant ArenavirusesCap binding and immune evasion revealed by Lassa nucleoprotein structureEffective oral favipiravir (T-705) therapy initiated after the onset of clinical disease in a model of arenavirus hemorrhagic FeverProteomic analysis of Pichindé virus infection identifies differential expression of prothymosin-alpha.Capped antigenomic RNA transcript facilitates rescue of a plant rhabdovirusComparative pathogenesis and systems biology for biodefense virus vaccine development.Drug discovery technologies and strategies for Machupo virus and other New World arenaviruses.Rescue from cloned cDNAs and in vivo characterization of recombinant pathogenic Romero and live-attenuated Candid #1 strains of Junin virus, the causative agent of Argentine hemorrhagic fever disease.The curious case of arenavirus entry, and its inhibition.Molecular mechanism of arenavirus assembly and budding.Development of a novel, guinea pig-specific IFN-γ ELISPOT assay and characterization of guinea pig cytomegalovirus GP83-specific cellular immune responses following immunization with a modified vaccinia virus Ankara (MVA)-vectored GP83 vaccineReceptor tyrosine kinase inhibitors that block replication of influenza a and other viruses.Characterization of virulence-associated determinants in the envelope glycoprotein of Pichinde virus.Role of lymphocytic choriomeningitis virus (LCMV) in understanding viral immunology: past, present and future.A Novel Live Pichinde Virus-Based Vaccine Vector Induces Enhanced Humoral and Cellular Immunity after a Booster Dose.Arenavirus reverse genetics for vaccine developmentReverse Genetics Approaches to Control Arenavirus.Inhibition of the type I interferon antiviral response during arenavirus infection.Characterization of the Glycoprotein Stable Signal Peptide in Mediating Pichinde Virus Replication and Virulence.In vitro and in vivo characterizations of pichinde viral nucleoprotein exoribonuclease functions.Lassa virus nucleoprotein mutants generated by reverse genetics induce a robust type I interferon response in human dendritic cells and macrophagesBiological roles and functional mechanisms of arenavirus Z protein in viral replication.Efficient rescue of recombinant Lassa virus reveals the influence of S segment noncoding regions on virus replication and virulenceIdentification of virulence determinants within the L genomic segment of the pichinde arenavirus.Recombinant Tri-Segmented Pichinde Virus as a Novel Live Viral Vaccine Platform.Molecular determinants of Pichinde virus infection of guinea pigs--a small animal model system for arenaviral hemorrhagic fevers.Differential Inhibition of Macrophage Activation by Lymphocytic Choriomeningitis Virus and Pichinde Virus Is Mediated by the Z Protein N-Terminal Domain.The Z proteins of pathogenic but not nonpathogenic arenaviruses inhibit RIG-I-like receptor-dependent interferon production.Establishment of Bisegmented and Trisegmented Reverse Genetics Systems to Generate Recombinant Pichindé Viruses.Assays to Demonstrate the Roles of Arenaviral Nucleoproteins (NPs) in Viral RNA Synthesis and in Suppressing Type I Interferon.Xapuri virus, a novel mammarenavirus: natural reassortment and increased diversity between New World viruses.
P2860
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P2860
Development of infectious clones for virulent and avirulent pichinde viruses: a model virus to study arenavirus-induced hemorrhagic fevers.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Development of infectious clon ...... us-induced hemorrhagic fevers.
@en
type
label
Development of infectious clon ...... us-induced hemorrhagic fevers.
@en
prefLabel
Development of infectious clon ...... us-induced hemorrhagic fevers.
@en
P2093
P2860
P356
P1433
P1476
Development of infectious clon ...... us-induced hemorrhagic fevers.
@en
P2093
Jialong Wang
Lisa McLay Schelde
Naveen Kumar
Shuiyun Lan
Yuying Liang
P2860
P304
P356
10.1128/JVI.00019-09
P407
P577
2009-04-22T00:00:00Z