Intracellular disposition and metabolism of fluorescently-labeled unmodified and modified oligonucleotides microinjected into mammalian cells. - Wikidata - awgldk - TriplyDB

Intracellular disposition and metabolism of fluorescently-labeled unmodified and modified oligonucleotides microinjected into mammalian cells.

Intracellular disposition and metabolism of fluorescently-labeled unmodified and modified oligonucleotides microinjected into mammalian cells.

http://www.wikidata.org/entity/Q40409131

about

Regulation of in vitro gene expression using antisense oligonucleotides or antisense expression plasmids transfected using starburst PAMAM dendrimers Visualizing telomere dynamics in living mammalian cells using PNA probes Transcription factor Egr-1 regulates glomerular mesangial cell proliferation A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine Expression of non-phosphorylatable paxillin mutants in canine tracheal smooth muscle inhibits tension development.Nucleocytoplasmic shuttling: a novel in vivo property of antisense phosphorothioate oligodeoxynucleotides.Visualizing the dynamics of viral replication in living cells via Tat peptide delivery of nuclease-resistant molecular beacons.Intracellular traffic of oligodeoxynucleotides in and out of the nucleus: effect of exportins and DNA structure Direct observation of specific messenger RNA in a single living cell under a fluorescence microscope The spherulites(TM): a promising carrier for oligonucleotide delivery.Efficient gene silencing by delivery of locked nucleic acid antisense oligonucleotides, unassisted by transfection reagents.Receptor-mediated endocytosis of phosphodiester oligonucleotides in the HepG2 cell line: evidence for non-conventional intracellular trafficking.Lipid-based systems for the intracellular delivery of genetic drugs.Functional analysis of newly discovered growth control genes: experimental approaches.Intracellular Distribution and Nuclear Activity of Antisense Oligonucleotides After Unassisted Uptake in Myoblasts and Differentiated Myotubes In Vitro.The use of antisense oligonucleotides in Xenopus oocytes.Antisense DNA downregulation of the ERBB2 oncogene measured by a flow cytometric assay.Subcellular trafficking of antisense oligonucleotides and down-regulation of bcl-2 gene expression in human melanoma cells using a fusogenic liposome delivery system.Vehicles for oligonucleotide delivery to tumours.Electroporation and microinjection successfully deliver single-stranded and duplex DNA into live cells as detected by FRET measurements.Clearance kinetics, biodistribution, and organ saturability of phosphorothioate oligodeoxynucleotides in mice Avoiding false-positive signals with nuclease-vulnerable molecular beacons in single living cells A cytosine analog that confers enhanced potency to antisense oligonucleotides.Divergent transforming growth factor-beta signaling in hepatic stellate cells after liver injury: functional effects on ECE-1 regulation Phosphorothioate antisense oligonucleotides induce the formation of nuclear bodies Fluorescence detection of single nucleotide polymorphisms using a universal molecular beacon.Shedding light on virus replication.Bioconjugation of oligonucleotides for treating liver fibrosis.A serum-resistant cytofectin for cellular delivery of antisense oligodeoxynucleotides and plasmid DNA Cellular delivery of siRNA and antisense oligonucleotides via receptor-mediated endocytosis.Recent advances in fluorescent nucleic acid probes for living cell studies.In-cell NMR and EPR spectroscopy of biomacromolecules.Prospects for the therapeutic use of antigene oligonucleotides.Design of a novel triple helix-forming oligodeoxyribonucleotide directed to the major promoter of the c-myc gene.Triplex formation by morpholino oligodeoxyribonucleotides in the HER-2/neu promoter requires the pyrimidine motif.Suppression of glioblastoma cell growth following antisense oligonucleotide-mediated inhibition of fibroblast growth factor receptor expression.Cellular penetration and antisense activity by a phenoxazine-substituted heptanucleotide.Different G proteins mediate somatostatin-induced inward rectifier K+ currents in murine brain and endocrine cells.Use of a simple fractionation method to evaluate binding, internalization and intracellular distribution of oligonucleotides in vascular smooth muscle cells.DNA nanotechnology from the test tube to the cell.

P2860

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P2860

Intracellular disposition and metabolism of fluorescently-labeled unmodified and modified oligonucleotides microinjected into mammalian cells.

http://www.wikidata.org/entity/Q40409131

description

1993 nî lūn-bûn

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Fisher TL

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P2860

Synthesis of DNA via deoxynucleoside H-phosphonate intermediates

The preparation and application of functionalised synthetic oligonucleotides: III. Use of H-phosphonate derivatives of protected amino-hexanol and mercapto-propanol or -hexanol

2'-O-methyl, 2'-O-ethyl oligoribonucleotides and phosphorothioate oligodeoxyribonucleotides as inhibitors of the in vitro U7 snRNP-dependent mRNA processing event

Phosphoramidate analogues of DNA: synthesis and thermal stability of heteroduplexes.

Intracellular availability of unmodified, phosphorothioated and liposomally encapsulated oligodeoxynucleotides for antisense activity.

Human promyelocytic leukemia HL-60 cell proliferation and c-myc protein expression are inhibited by an antisense pentadecadeoxynucleotide targeted against c-myc mRNA.

2'-O-alkyl oligoribonucleotides as antisense probes.

Characterization of oligonucleotide transport into living cells.

Effects of phosphorothioate capping on antisense oligonucleotide stability, hybridization and antiviral efficacy versus herpes simplex virus infection.

Modified deoxyoligonucleotides stable to exonuclease degradation in serum.

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