Implication of the MAGI-1b/PTEN signalosome in stabilization of adherens junctions and suppression of invasiveness.
about
PTEN tumor suppressor associates with NHERF proteins to attenuate PDGF receptor signaling.Binding of PTEN to specific PDZ domains contributes to PTEN protein stability and phosphorylation by microtubule-associated serine/threonine kinasesMAGI-1 is required for Rap1 activation upon cell-cell contact and for enhancement of vascular endothelial cadherin-mediated cell adhesion.PtdIns(3,4,5)P(3)-dependent and -independent roles for PTEN in the control of cell migrationFocus on PTEN RegulationE-cadherin's dark side: possible role in tumor progressionValidated prediction of pro-invasive growth factors using a transcriptome-wide invasion signature derived from a complex 3D invasion assayNa+/H+ exchanger regulatory factor 1 inhibits platelet-derived growth factor signaling in breast cancer cellsHigh intensity focused ultrasound inhibits melanoma cell migration and metastasis through attenuating microRNA-21-mediated PTEN suppression.PI3K and Erk MAPK mediate ErbB signaling in Xenopus gastrulation.NADPH oxidase 1 modulates WNT and NOTCH1 signaling to control the fate of proliferative progenitor cells in the colonGene expression profile of androgen modulated genes in the murine fetal developing lungGenetic and clonal dissection of murine small cell lung carcinoma progression by genome sequencing.The PTEN phosphatase controls intestinal epithelial cell polarity and barrier function: role in colorectal cancer progression.Reduced surface expression of epithelial E-cadherin evoked by interferon-gamma is Fyn kinase-dependentCooperative interactions of PTEN deficiency and RAS activation in melanoma metastasisPre-metazoan origins and evolution of the cadherin adhesome.Phosphoinositide 3-kinase regulatory subunit p85alpha suppresses insulin action via positive regulation of PTEN.Apoptosis regulator through modulating IAP expression (ARIA) controls the PI3K/Akt pathway in endothelial and endothelial progenitor cells.Involvement of TGFβ-induced phosphorylation of the PTEN C-terminus on TGFβ-induced acquisition of malignant phenotypes in lung cancer cells.Phosphoinositides in cell architecture.TRIP6: an adaptor protein that regulates cell motility, antiapoptotic signaling and transcriptional activity.The PDZ3 domain of the cellular scaffolding protein MAGI-1 interacts with the Coxsackievirus and adenovirus receptor (CAR).NHERFs, NEP, MAGUKs, and more: interactions that regulate PTEN.Putting into practice domain-linear motif interaction predictions for exploration of protein networks.Bioinformatics approach to predict target genes for dysregulated microRNAs in hepatocellular carcinoma: study on a chemically-induced HCC mouse model.Quantifying domain-ligand affinities and specificities by high-throughput holdup assay.Small-molecule inhibition of PTPRZ reduces tumor growth in a rat model of glioblastoma.Magi Is Associated with the Par Complex and Functions Antagonistically with Bazooka to Regulate the Apical Polarity ComplexThe PDZ1 and PDZ3 domains of MAGI-1 regulate the eight-exon isoform of the coxsackievirus and adenovirus receptor.Expression of NF-κB and PTEN in primary epithelial ovarian carcinoma and the correlation with chemoresistance.Cell polarity proteins: common targets for tumorigenic human viruses.MEK1 is required for PTEN membrane recruitment, AKT regulation, and the maintenance of peripheral toleranceEpithelial morphological reversion drives Profilin-1-induced elevation of p27(kip1) in mesenchymal triple-negative human breast cancer cells through AMP-activated protein kinase activation.Hypoxia-induced modulation of PTEN activity and EMT phenotypes in lung cancers.Phosphatase and tensin homologue deleted on chromosome 10Retinal degeneration triggered by inactivation of PTEN in the retinal pigment epithelium.Phosphatidyl inositol 3-kinase signaling in hypothalamic proopiomelanocortin neurons contributes to the regulation of glucose homeostasis.Analysis of PTEN complex assembly and identification of heterogeneous nuclear ribonucleoprotein C as a component of the PTEN-associated complex.PTEN function: the long and the short of it.
P2860
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P2860
Implication of the MAGI-1b/PTEN signalosome in stabilization of adherens junctions and suppression of invasiveness.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Implication of the MAGI-1b/PTE ...... d suppression of invasiveness.
@en
type
label
Implication of the MAGI-1b/PTE ...... d suppression of invasiveness.
@en
prefLabel
Implication of the MAGI-1b/PTE ...... d suppression of invasiveness.
@en
P2093
P356
P1433
P1476
Implication of the MAGI-1b/PTE ...... d suppression of invasiveness.
@en
P2093
Eric Chastre
Erik Bruyneel
Frans van Roy
Jolanda van Hengel
Larissa Kotelevets
Marc Mareel
P304
P356
10.1096/FJ.04-1942FJE
P407
P577
2004-11-01T00:00:00Z