Trastuzumab down-regulates Bcl-2 expression and potentiates apoptosis induction by Bcl-2/Bcl-XL bispecific antisense oligonucleotides in HER-2 gene--amplified breast cancer cells.

Trastuzumab down-regulates Bcl-2 expression and potentiates apoptosis induction by Bcl-2/Bcl-XL bispecific antisense oligonucleotides in HER-2 gene--amplified breast cancer cells.

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http://www.wikidata.org/entity/Q40486730
Artemin, a member of the glial cell line-derived neurotrophic factor family of ligands, is HER2-regulated and mediates acquired trastuzumab resistance by promoting cancer stem cell-like behavior in mammary carcinoma cells.Expression of the apoptosis-related genes BCL-2 and BAD in human breast carcinoma and their associated relationship with chemosensitivity.ERBB3 knockdown induces cell cycle arrest and activation of Bak and Bax-dependent apoptosis in colon cancer cells.The mitogen-activated protein kinase (MAPK) cascade controls phosphatase and tensin homolog (PTEN) expression through multiple mechanisms.Regulation of anti-apoptotic signaling by Kruppel-like factors 4 and 5 mediates lapatinib resistance in breast cancer.Targeting Bcl-2 in Herceptin-Resistant Breast Cancer Cell Lines.The chemomodulatory effects of resveratrol and didox on herceptin cytotoxicity in breast cancer cell lines.Survival of HER2-Positive Breast Cancer Cells: Receptor Signaling to Apoptotic Control Centers.Leptin-signaling inhibition results in efficient anti-tumor activity in estrogen receptor positive or negative breast cancer.Gene expression profile and response to trastuzumab-docetaxel-based treatment in breast carcinoma.PTEN status is a crucial determinant of the functional outcome of combined MEK and mTOR inhibition in cancer.Absence of p53 gene expression in selenium molecular prevention of chemically induced hepatocarcinogenesis in rats.188Re-HYNIC-trastuzumab enhances the effect of apoptosis induced by trastuzumab in HER2-overexpressing breast cancer cells.Aberrant activation of the mTOR pathway and anti-tumour effect of everolimus on oesophageal squamous cell carcinoma.Dual mechanisms of sHA 14-1 in inducing cell death through endoplasmic reticulum and mitochondria.Lapatinib, a HER2 tyrosine kinase inhibitor, induces stabilization and accumulation of HER2 and potentiates trastuzumab-dependent cell cytotoxicity.Release of HER2 repression of trefoil factor 3 (TFF3) expression mediates trastuzumab resistance in HER2+/ER+ mammary carcinoma.
P2860

Trastuzumab down-regulates Bcl-2 expression and potentiates apoptosis induction by Bcl-2/Bcl-XL bispecific antisense oligonucleotides in HER-2 gene--amplified breast cancer cells.

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http://www.wikidata.org/entity/Q40486730
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2004 nî lūn-bûn
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2004年の論文
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2004年学术文章
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Trastuzumab down-regulates Bcl ...... amplified breast cancer cells.
@en
type
label
Trastuzumab down-regulates Bcl ...... amplified breast cancer cells.
@en
prefLabel
Trastuzumab down-regulates Bcl ...... amplified breast cancer cells.
@en
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698
P356
P1433
P1476
Trastuzumab down-regulates Bcl ...... -amplified breast cancer cells
@en
P2093
P304
P31
P356
10.1158/1078-0432.CCR-04-0908
P407
P433
P478
P50
P577
P698