Expression of IglC is necessary for intracellular growth and induction of apoptosis in murine macrophages by Francisella tularensis.
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Dissection of Francisella-Host Cell Interactions in Dictyostelium discoideum.Rationally designed tularemia vaccines.Francisella tularensis subsp. tularensis Schu S4 disulfide bond formation protein B, but not an RND-type efflux pump, is required for virulenceIdentification of genes contributing to the virulence of Francisella tularensis SCHU S4 in a mouse intradermal infection modelAkt and SHIP modulate Francisella escape from the phagosome and induction of the Fas-mediated death pathway.The Francisella pathogenicity island protein IglA localizes to the bacterial cytoplasm and is needed for intracellular growthRipA, a cytoplasmic membrane protein conserved among Francisella species, is required for intracellular survivalGlobal transcriptional response to mammalian temperature provides new insight into Francisella tularensis pathogenesis.Interrelationship between dendritic cell trafficking and Francisella tularensis dissemination following airway infection.Phagosomal retention of Francisella tularensis results in TIRAP/Mal-independent TLR2 signaling.Characterization and Vaccine Potential of Membrane Vesicles Produced by Francisella noatunensis subsp. orientalis in an Adult Zebrafish Model.Nucleolin, a shuttle protein promoting infection of human monocytes by Francisella tularensis.Regulation of virulence gene transcripts by the Francisella novicida orphan response regulator PmrA: role of phosphorylation and evidence of MglA/SspA interaction.Francisella tularensis DeltapyrF mutants show that replication in nonmacrophages is sufficient for pathogenesis in vivo.Pivotal role of the Francisella tularensis heat-shock sigma factor RpoH.Characterization of the pathogenicity island protein PdpA and its role in the virulence of Francisella novicidaMacrophage replication screen identifies a novel Francisella hydroperoxide resistance protein involved in virulence.IglC and PdpA are important for promoting Francisella invasion and intracellular growth in epithelial cellsIntranasal vaccination with a defined attenuated Francisella novicida strain induces gamma interferon-dependent antibody-mediated protection against tularemia.Mast cell/IL-4 control of Francisella tularensis replication and host cell death is associated with increased ATP production and phagosomal acidificationDeletion of TolC orthologs in Francisella tularensis identifies roles in multidrug resistance and virulenceAttenuated Francisella novicida transposon mutants protect mice against wild-type challenge.Tryptophan prototrophy contributes to Francisella tularensis evasion of gamma interferon-mediated host defense.The capBCA Locus is Required for Intracellular Growth of Francisella tularensis LVS.Mac-1+ cells are the predominant subset in the early hepatic lesions of mice infected with Francisella tularensis.In vivo negative selection screen identifies genes required for Francisella virulenceDifferential infection of mononuclear phagocytes by Francisella tularensis: role of the macrophage mannose receptor.Using host-pathogen protein interactions to identify and characterize Francisella tularensis virulence factors.Genome-wide identification of Francisella tularensis virulence determinantsFrancisella tularensis: taxonomy, genetics, and Immunopathogenesis of a potential agent of biowarfare.The biochemical properties of the Francisella pathogenicity island (FPI)-encoded proteins IglA, IglB, IglC, PdpB and DotU suggest roles in type VI secretion.The live vaccine strain of Francisella tularensis replicates in human and murine macrophages but induces only the human cells to secrete proinflammatory cytokines.Francisella tularensis tmRNA system mutants are vulnerable to stress, avirulent in mice, and provide effective immune protectionMacrophage cell death upon intracellular bacterial infection.Characterization and application of a glucose-repressible promoter in Francisella tularensisTemporal transcriptional response during infection of type II alveolar epithelial cells with Francisella tularensis live vaccine strain (LVS) supports a general host suppression and bacterial uptake by macropinocytosis.Macrophage proinflammatory response to Francisella tularensis live vaccine strain requires coordination of multiple signaling pathways.Recombinant attenuated Listeria monocytogenes vaccine expressing Francisella tularensis IglC induces protection in mice against aerosolized Type A F. tularensis.Hfq, a novel pleiotropic regulator of virulence-associated genes in Francisella tularensis.Identification of migR, a regulatory element of the Francisella tularensis live vaccine strain iglABCD virulence operon required for normal replication and trafficking in macrophages.
P2860
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P2860
Expression of IglC is necessary for intracellular growth and induction of apoptosis in murine macrophages by Francisella tularensis.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Expression of IglC is necessar ...... ges by Francisella tularensis.
@en
type
label
Expression of IglC is necessar ...... ges by Francisella tularensis.
@en
prefLabel
Expression of IglC is necessar ...... ges by Francisella tularensis.
@en
P1476
Expression of IglC is necessar ...... ges by Francisella tularensis.
@en
P2093
Igor Golovliov
Xin-He Lai
P304
P356
10.1016/J.MICPATH.2004.07.002
P577
2004-11-01T00:00:00Z