Thyroid hormone potentiates glucocorticoid-evoked airway Na+ transport without affecting alpha-ENaC transcription.
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The Concise Guide to PHARMACOLOGY 2013/14: ion channelsAMP-activated protein kinase (AMPK)-dependent and -independent pathways regulate hypoxic inhibition of transepithelial Na+ transport across human airway epithelial cells.Glucocorticoids can activate the alpha-ENaC gene promoter independently of SGK1.AICAR activates AMPK and alters PIP2 association with the epithelial sodium channel ENaC to inhibit Na+ transport in H441 lung epithelial cells.A Ba2+-resistant, acid-sensitive K+ conductance in Na+-absorbing H441 human airway epithelial cells.Expression of intermediate-conductance, Ca2+-activated K+ channel (KCNN4) in H441 human distal airway epithelial cells.Reduced ENaC protein abundance contributes to the lower blood pressure observed in pendrin-null mice.
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Q30486735-E335424D-A463-40BE-98AF-E8B3D59F2324Q36346926-FEC4329E-6312-45FD-8F0C-6BDB897F3F85Q37389065-2E2C016E-574F-4C2B-A487-A2A44630D782Q39955492-8692D897-3E27-4403-913A-EF971C4F8E4AQ40174808-EE742E7A-D8A1-414A-ABC2-B5D5CF2FDBC5Q40269132-EBF56CED-76B3-4DAC-B347-5DE97595D4F2Q50670408-AC2C557C-3BE4-4B8F-BC30-C2BE16E3CFC6
P2860
Thyroid hormone potentiates glucocorticoid-evoked airway Na+ transport without affecting alpha-ENaC transcription.
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name
Thyroid hormone potentiates gl ...... ting alpha-ENaC transcription.
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Thyroid hormone potentiates gl ...... ting alpha-ENaC transcription.
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prefLabel
Thyroid hormone potentiates gl ...... ting alpha-ENaC transcription.
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Thyroid hormone potentiates gl ...... ting alpha-ENaC transcription.
@en
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Burchell A
Ramminger SJ
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P304
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10.1016/J.FEBSLET.2004.09.030
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P577
2004-10-01T00:00:00Z