Antisense probes containing 2-aminoadenosine allow efficient depletion of U5 snRNP from HeLa splicing extracts.
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Evidence that U5 snRNP recognizes the 3' splice site for catalytic step II in mammalsSMNrp is an essential pre-mRNA splicing factor required for the formation of the mature spliceosome.The 5' end of yeast 5.8S rRNA is generated by exonucleases from an upstream cleavage siteThe spliceosome assembly pathway in mammalian extractsA U5 small nuclear ribonucleoprotein particle protein involved only in the second step of pre-mRNA splicing in Saccharomyces cerevisiae.Prp31p promotes the association of the U4/U6 x U5 tri-snRNP with prespliceosomes to form spliceosomes in Saccharomyces cerevisiae.Central region of the human splicing factor Hprp3p interacts with Hprp4pThree novel functional variants of human U5 small nuclear RNAPyrazolo[3,4-d]pyrimidine nucleic acids: adjustment of dA-dT to dG-dC base pair stability.Propynyl groups in duplex DNA: stability of base pairs incorporating 7-substituted 8-aza-7-deazapurines or 5-substituted pyrimidinesFunctional analysis of the U5 snRNA loop 1 in the second catalytic step of yeast pre-mRNA splicing.Proximity of the invariant loop of U5 snRNA to the second intron residue during pre-mRNA splicing.Efficient priming of PCR with short oligonucleotides conjugated to a minor groove binder.Requirements for U2 snRNP addition to yeast pre-mRNA.Mammalian U6 small nuclear RNA undergoes 3' end modifications within the spliceosome.Uncoupling two functions of the U1 small nuclear ribonucleoprotein particle during in vitro splicingAn ATP-independent U2 small nuclear ribonucleoprotein particle/precursor mRNA complex requires both splice sites and the polypyrimidine tract.Target-specific arrest of mRNA translation by antisense 2'-O-alkyloligoribonucleotides.Antisense oligonucleotide binding to U5 snRNP induces a conformational change that exposes the conserved loop of U5 snRNA.G/C-modified oligodeoxynucleotides with selective complementarity: synthesis and hybridization properties.A yeast splicing factor is localized in discrete subnuclear domains.Synthesis and hybridization properties of oligonucleotides containing 2'-O-modified ribonucleotides.Antisense oligonucleotides made of 2'-O-alkylRNA: their properties and applications in RNA biochemistry.Antisense probes targeted to an internal domain in U2 snRNP specifically inhibit the second step of pre-mRNA splicing.Reconstitution of functional mammalian U4 small nuclear ribonucleoprotein: Sm protein binding is not essential for splicing in vitro.In vitro reconstitution of mammalian U2 and U5 snRNPs active in splicing: Sm proteins are functionally interchangeable and are essential for the formation of functional U2 and U5 snRNPs.Restoration of correct splicing in IVSI-110 mutation of β-globin gene with antisense oligonucleotides: implications and applications in functional assay development.Roles of U4 and U6 snRNAs in the assembly of splicing complexes.Reconstituted mammalian U4/U6 snRNP complements splicing: a mutational analysis.Nuclease resistant ribozymes with high catalytic activity.Roles of PRP8 protein in the assembly of splicing complexes.Transcription-dependent colocalization of the U1, U2, U4/U6, and U5 snRNPs in coiled bodies.Synthetic lethal mutations suggest interactions between U5 small nuclear RNA and four proteins required for the second step of splicing
P2860
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P2860
Antisense probes containing 2-aminoadenosine allow efficient depletion of U5 snRNP from HeLa splicing extracts.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年学术文章
@wuu
1991年学术文章
@zh-cn
1991年学术文章
@zh-hans
1991年学术文章
@zh-my
1991年学术文章
@zh-sg
1991年學術文章
@yue
1991年學術文章
@zh
1991年學術文章
@zh-hant
name
Antisense probes containing 2- ...... P from HeLa splicing extracts.
@en
type
label
Antisense probes containing 2- ...... P from HeLa splicing extracts.
@en
prefLabel
Antisense probes containing 2- ...... P from HeLa splicing extracts.
@en
P2093
P2860
P356
P1476
Antisense probes containing 2- ...... P from HeLa splicing extracts.
@en
P2093
P2860
P304
P356
10.1093/NAR/19.12.3193
P577
1991-06-01T00:00:00Z