Calmodulin mediates Ca2+ sensitivity of sodium channels.
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Multiple C-terminal tail Ca(2+)/CaMs regulate Ca(V)1.2 function but do not mediate channel dimerizationCa2+/calmodulin-dependent protein kinase II (CaMKII) regulates cardiac sodium channel NaV1.5 gating by multiple phosphorylation sitesSolution NMR structure of Apo-calmodulin in complex with the IQ motif of human cardiac sodium channel NaV1.5Role of Ca2+/calmodulin-dependent protein kinase (CaMK) in excitation-contraction coupling in the heartSolution NMR structure of the C-terminal EF-hand domain of human cardiac sodium channel NaV1.5Calcium-Sensing Receptor: A Key Target for Extracellular Calcium Signaling in NeuronsChannelopathies from mutations in the cardiac sodium channel protein complexChannelopathy pathogenesis in autism spectrum disordersTowards a Unified Theory of Calmodulin Regulation (Calmodulation) of Voltage-Gated Calcium and Sodium ChannelsSolution Structure of the NaV1.2 C-terminal EF-hand DomainCrystallographic basis for calcium regulation of sodium channelsCrystal Structure of the Ternary Complex of a NaV C-Terminal Domain, a Fibroblast Growth Factor Homologous Factor, and CalmodulinPost-translational modifications of the cardiac Na channel: contribution of CaMKII-dependent phosphorylation to acquired arrhythmiasNa+ channel regulation by Ca2+/calmodulin and Ca2+/calmodulin-dependent protein kinase II in guinea-pig ventricular myocytesIncreased activities of Na+/K+-ATPase and Ca2+/Mg2+-ATPase in the frontal cortex and cerebellum of autistic individualsSodium channel carboxyl-terminal residue regulates fast inactivation.Energetics of calmodulin domain interactions with the calmodulin binding domain of CaMKII.Calcium-dependent energetics of calmodulin domain interactions with regulatory regions of the Ryanodine Receptor Type 1 (RyR1)Regulation of the NaV1.5 cytoplasmic domain by calmodulinDiseases caused by mutations in Nav1.5 interacting proteinsInsights into voltage-gated calcium channel regulation from the structure of the CaV1.2 IQ domain-Ca2+/calmodulin complex.Calmodulin regulates current density and frequency-dependent inhibition of sodium channel Nav1.8 in DRG neurons.The role of calmodulin recruitment in Ca2+ stimulation of adenylyl cyclase type 8.Calcium-dependent regulation of the voltage-gated sodium channel hH1: intrinsic and extrinsic sensors use a common molecular switchRelating form and function of EF-hand calcium binding proteins.Mechanisms of a human skeletal myotonia produced by mutation in the C-terminus of NaV1.4: is Ca2+ regulation defective?Identification of novel interaction sites that determine specificity between fibroblast growth factor homologous factors and voltage-gated sodium channels.Calcium and arrhythmogenesis.Ca2+/calmodulin-dependent protein kinase II regulates cardiac Na+ channelsArrhythmogenic Biophysical Phenotype for SCN5A Mutation S1787N Depends upon Splice Variant Background and Intracellular Acidosis.Inhibition of voltage-gated Na(+) current by nanosecond pulsed electric field (nsPEF) is not mediated by Na(+) influx or Ca(2+) signalingSodium channel mutations in epilepsy and other neurological disorders.Perturbation of sodium channel structure by an inherited Long QT Syndrome mutation.Calmodulin regulation of Nav1.4 current: role of binding to the carboxyl terminus.Modulation of cardiac Na(+) and Ca(2+) currents by CaM and CaMKII.Late sodium current in failing heart: friend or foe?Calmodulin and CaMKII as molecular switches for cardiac ion channels.Late sodium current is a new therapeutic target to improve contractility and rhythm in failing heart.Calmodulin mutations associated with recurrent cardiac arrest in infants.Dynamics of the late Na(+) current during cardiac action potential and its contribution to afterdepolarizations.
P2860
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P2860
Calmodulin mediates Ca2+ sensitivity of sodium channels.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Calmodulin mediates Ca2+ sensitivity of sodium channels.
@en
type
label
Calmodulin mediates Ca2+ sensitivity of sodium channels.
@en
prefLabel
Calmodulin mediates Ca2+ sensitivity of sodium channels.
@en
P2093
P2860
P356
P1476
Calmodulin mediates Ca2+ sensitivity of sodium channels.
@en
P2093
Huajun Liu
Michihiro Tateyama
Robert S Kass
Smita Ghosh
P2860
P304
45004-45012
P356
10.1074/JBC.M407286200
P407
P577
2004-08-16T00:00:00Z