Activation of Rac1 by paxillin-Crk-DOCK180 signaling complex is antagonized by Rap1 in migrating NBT-II cells.
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Paxillin comes of ageRole of Rap1B and tumor suppressor PTEN in the negative regulation of lysophosphatidic acid--induced migration by isoproterenol in glioma cellsThe dynamics of spatio-temporal Rho GTPase signaling: formation of signaling patternsThe focal adhesion-localized CdGAP regulates matrix rigidity sensing and durotaxisRole played by paxillin and paxillin tyrosine phosphorylation in hepatocyte growth factor/sphingosine-1-phosphate-mediated reactive oxygen species generation, lamellipodia formation, and endothelial barrier functionDistinct roles for Crk adaptor isoforms in actin reorganization induced by extracellular signalsSrc and FAK kinases cooperate to phosphorylate paxillin kinase linker, stimulate its focal adhesion localization, and regulate cell spreading and protrusiveness.The adapter protein CrkII regulates neuronal Wiskott-Aldrich syndrome protein, actin polymerization, and tension development during contractile stimulation of smooth muscle.Paxillin enables attachment-independent tyrosine phosphorylation of focal adhesion kinase and transformation by RAS.Cross-correlated fluctuation analysis reveals phosphorylation-regulated paxillin-FAK complexes in nascent adhesions.Focal adhesion kinase as a regulator of cell tension in the progression of cancer.Integrin signalling in directed cell migration.Stochastic Dynamics of Membrane Protrusion Mediated by the DOCK180/Rac Pathway in Migrating CellsMaternal embryonic leucine zipper kinase enhances gastric cancer progression via the FAK/Paxillin pathwayDifferences in adhesion and protrusion properties correlate with differences in migration speed under EGF stimulation.Phosphoinositide-3 kinase-Rac1-c-Jun NH2-terminal kinase signaling mediates collagen I-induced cell scattering and up-regulation of N-cadherin expression in mouse mammary epithelial cells.TIMP-2 upregulates RECK expression via dephosphorylation of paxillin tyrosine residues 31 and 118.Reorganization of the integrin alpha2 subunit controls cell adhesion and cancer cell invasion in prostate cancerc-Abl mediated tyrosine phosphorylation of paxillin regulates LPS-induced endothelial dysfunction and lung injuryCentral role of paxillin phosphorylation in regulation of LFA-1 integrins activity and lymphocyte migration.Hypoxia/reoxygenation-experienced cancer cell migration and metastasis are regulated by Rap1- and Rac1-GTPase activation via the expression of thymosin beta-4.Expression of Paxillin is Correlated with Clinical Prognosis in Colorectal Cancer PatientsDynamic phosphorylation of tyrosine 665 in pseudopodium-enriched atypical kinase 1 (PEAK1) is essential for the regulation of cell migration and focal adhesion turnoverRegulation of tumor cell migration by protein tyrosine phosphatase (PTP)-proline-, glutamate-, serine-,and threonine-rich sequence (PEST).Roles of Rap1 signaling in tumor cell migration and invasionNeutrophil transmigration, focal adhesion kinase and endothelial barrier function.Roles for crk in cancer metastasis and invasion.I'm coming to GEF you: Regulation of RhoGEFs during cell migration.Pressure activates colon cancer cell adhesion via paxillin phosphorylation, Crk, Cas, and Rac1.Nuclear SIPA1 activates integrin β1 promoter and promotes invasion of breast cancer cells.PTTG induces EMT through integrin αVβ3-focal adhesion kinase signaling in lung cancer cells.Focal adhesion kinase regulates cell-cell contact formation in epithelial cells via modulation of Rho.Preclinical anticancer activity of the potent, oral Src inhibitor AZD0530KSHV-TK is a tyrosine kinase that disrupts focal adhesions and induces Rho-mediated cell contraction.Migrating anterior mesoderm cells and intercalating trunk mesoderm cells have distinct responses to Rho and Rac during Xenopus gastrulation.Molecular mechanisms for enhancement of stromal cell-derived factor 1-induced chemotaxis by platelet endothelial cell adhesion molecule 1 (PECAM-1).CRK binds BCAR1 and or PXNDOCK180:ELMO binds CRKp104 binds to Rac1 and reduces its activity during myotube differentiation of C2C12 cell
P2860
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P2860
Activation of Rac1 by paxillin-Crk-DOCK180 signaling complex is antagonized by Rap1 in migrating NBT-II cells.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Activation of Rac1 by paxillin ...... ap1 in migrating NBT-II cells.
@en
type
label
Activation of Rac1 by paxillin ...... ap1 in migrating NBT-II cells.
@en
prefLabel
Activation of Rac1 by paxillin ...... ap1 in migrating NBT-II cells.
@en
P2093
P2860
P356
P1476
Activation of Rac1 by paxillin ...... ap1 in migrating NBT-II cells.
@en
P2093
Ana M Vallés
Brigitte Boyer
Maud Beuvin
P2860
P304
44490-44496
P356
10.1074/JBC.M405144200
P407
P577
2004-08-12T00:00:00Z