Colon carcinoma cell growth is associated with prostaglandin E2/EP4 receptor-evoked ERK activation.
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E-type prostanoid receptor 4 (EP4) in disease and therapyProstaglandin E receptor 4 (EP4) promotes colonic tumorigenesis.Ets-1 and runx2 regulate transcription of a metastatic gene, osteopontin, in murine colorectal cancer cellsInhibition of 11beta-hydroxysteroid dehydrogenase type II selectively blocks the tumor COX-2 pathway and suppresses colon carcinogenesis in mice and humansThe role of PGE2 receptor EP4 in pathologic ocular angiogenesis.Proneoplastic effects of PGE2 mediated by EP4 receptor in colorectal cancer.COX-2 and prostaglandin EP3/EP4 signaling regulate the tumor stromal proangiogenic microenvironment via CXCL12-CXCR4 chemokine systems.Genetic variation in prostaglandin E2 synthesis and signaling, prostaglandin dehydrogenase, and the risk of colorectal adenoma.Activation of lipid metabolism contributes to interleukin-8 production during Chlamydia trachomatis infection of cervical epithelial cellsCyclooxygenases and lipoxygenases in cancer.Prostaglandin E2 receptors in asthma and in chronic rhinosinusitis/nasal polyps with and without aspirin hypersensitivity.Understanding the role of prostaglandin E2 in regulating human platelet activity in health and diseaseThe interrelationships of the gut microbiome and inflammation in colorectal carcinogenesis.Aspirin and COX-2 inhibitor use in patients with stage III colon cancerProstacyclin regulates bone growth via the Epac/Rap1 pathway.Prostaglandin E2 receptor EP4 as the common target on cancer cells and macrophages to abolish angiogenesis, lymphangiogenesis, metastasis, and stem-like cell functionsThe omega-3 polyunsaturated fatty acid eicosapentaenoic acid inhibits mouse MC-26 colorectal cancer cell liver metastasis via inhibition of PGE2-dependent cell motility.Prostaglandin E2 activates the mTORC1 pathway through an EP4/cAMP/PKA- and EP1/Ca2+-mediated mechanism in the human pancreatic carcinoma cell line PANC-1Inflammation and colorectal cancer: colitis-associated neoplasia.Deletion of cyclooxygenase-2 inhibits K-ras-induced lung carcinogenesis.The syndecan-4/protein kinase Cα pathway mediates prostaglandin E2-induced extracellular regulated kinase (ERK) activation in endothelial cells and angiogenesis in vivo.11β-Hydroxysteroid Dehydrogenase Type II is a Potential Target for Prevention of Colorectal TumorigenesisTime-dependent effects of imatinib in human leukaemia cells: a kinetic NMR-profiling study.Tumor-growth-promoting cyclooxygenase-2 prostaglandin E2 pathway provides medulloblastoma therapeutic targetsRationale for the design of an oncology trial using a generic targeted therapy multi‑drug regimen for NSCLC patients without treatment options (Review)Group X phospholipase A2 stimulates the proliferation of colon cancer cells by producing various lipid mediators.Açaí Berries Inhibit Colon Tumorigenesis in Azoxymethane/Dextran Sulfate Sodium-Treated MiceRegulation of endothelial cell functions by basement membrane- and arachidonic acid-derived products.Possible link between cyclooxygenase-inhibiting and antitumor properties of propofol.Eicosanoid signalling pathways in the development and progression of colorectal cancer: novel approaches for prevention/intervention.Activation of peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) increases the expression of prostaglandin E2 receptor subtype EP4. The roles of phosphatidylinositol 3-kinase and CCAAT/enhancer-binding protein beta.Prostaglandin E2-Induced COX-2 Expressions via EP2 and EP4 Signaling Pathways in Human LoVo Colon Cancer Cells.The EP4 antagonist, L-161,982, induces apoptosis, cell cycle arrest, and inhibits prostaglandin E2-induced proliferation in oral squamous carcinoma Tca8113 cells.Synthesis and characterization of celecoxib derivatives as possible anti-inflammatory, analgesic, antioxidant, anticancer and anti-HCV agents.The first characterization of free radicals formed from cellular COX-catalyzed peroxidation.EP4 receptor signalling in immature B cells involves cAMP and NF-κB dependent pathways.MicroRNA-101 (miR-101) post-transcriptionally regulates the expression of EP4 receptor in colon cancers.EGFR signaling upregulates expression of microsomal prostaglandin E synthase-1 in cancer cells leading to enhanced tumorigenicity.Bezielle (BZL101)-induced oxidative stress damage followed by redistribution of metabolic fluxes in breast cancer cells: a combined proteomic and metabolomic study.c-Jun N-terminal kinase (JNK1) upregulates XIAP-associated factor 1 (XAF1) through interferon regulatory factor 1 (IRF-1) in gastrointestinal cancer.
P2860
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P2860
Colon carcinoma cell growth is associated with prostaglandin E2/EP4 receptor-evoked ERK activation.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Colon carcinoma cell growth is ...... eceptor-evoked ERK activation.
@en
type
label
Colon carcinoma cell growth is ...... eceptor-evoked ERK activation.
@en
prefLabel
Colon carcinoma cell growth is ...... eceptor-evoked ERK activation.
@en
P2093
P2860
P356
P1476
Colon carcinoma cell growth is ...... receptor-evoked ERK activation
@en
P2093
Ambra Pozzi
Ines Macias-Perez
Jason D Morrow
Jorge H Capdevila
Richard M Breyer
Shouzuo Wei
Xuexian Yan
P2860
P304
29797-29804
P356
10.1074/JBC.M313989200
P407
P50
P577
2004-05-03T00:00:00Z