5-Aminoimidazole-4-carboxamide riboside suppresses lipopolysaccharide-induced TNF-alpha production through inhibition of phosphatidylinositol 3-kinase/Akt activation in RAW 264.7 murine macrophages.
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5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside (AICAR) attenuates the expression of LPS- and Abeta peptide-induced inflammatory mediators in astroglia.Controls of Nuclear Factor-Kappa B Signaling Activity by 5'-AMP-Activated Protein Kinase Activation With Examples in Human Bladder Cancer CellsPKC-dependent human monocyte adhesion requires AMPK and Syk activationAICAR Enhances the Phagocytic Ability of Macrophages towards Apoptotic Cells through P38 Mitogen Activated Protein Kinase Activation Independent of AMP-Activated Protein KinaseThe orphan nuclear receptor SHP acts as a negative regulator in inflammatory signaling triggered by Toll-like receptorsAMPK-independent inhibition of human macrophage ER stress response by AICAR.Activation of AMP-activated protein kinase stimulates the nuclear localization of glyceraldehyde 3-phosphate dehydrogenase in human diploid fibroblastsAkt Cys-310-targeted inhibition by hydroxylated benzene derivatives is tightly linked to their immunosuppressive effectsMetformin suppresses lipopolysaccharide (LPS)-induced inflammatory response in murine macrophages via activating transcription factor-3 (ATF-3) induction.Metformin Improves Insulin Signaling in Obese Rats via Reduced IKKbeta Action in a Fiber-Type Specific Manner.The full capacity of AICAR to reduce obesity-induced inflammation and insulin resistance requires myeloid SIRT1Metformin inhibits HMGB1 release in LPS-treated RAW 264.7 cells and increases survival rate of endotoxaemic miceAnti-inflammatory effects of thiazolidinediones in human airway smooth muscle cells.Resveratrol activates AMPK and suppresses LPS-induced NF-κB-dependent COX-2 activation in RAW 264.7 macrophage cells.AICAR attenuates organ injury and inflammatory response after intestinal ischemia and reperfusion.AMP-activated protein kinase enhances the phagocytic ability of macrophages and neutrophils.Post-treatment with the combination of 5-aminoimidazole-4-carboxyamide ribonucleoside and carnitine improves renal function after ischemia/reperfusion injuryMondoA senses adenine nucleotides: transcriptional induction of thioredoxin-interacting proteinMetformin attenuates hyperoxia-induced lung injury in neonatal rats by reducing the inflammatory responseToll-like receptor 4 engagement inhibits adenosine 5'-monophosphate-activated protein kinase activation through a high mobility group box 1 protein-dependent mechanismAminoimidazole carboxamide ribonucleotide ameliorates experimental autoimmune uveitisAMP-activated protein kinase activation by 5-aminoimidazole-4-carbox-amide-1-β-D-ribofuranoside (AICAR) reduces lipoteichoic acid-induced lung inflammation.Activation of AMPK attenuates neutrophil proinflammatory activity and decreases the severity of acute lung injury.Mitochondria and AMP-activated protein kinase-dependent mechanism of efferocytosisThe role of AMPK in psychosine mediated effects on oligodendrocytes and astrocytes: implication for Krabbe diseaseAMPKα1 deficiency amplifies proinflammatory myeloid APC activity and CD40 signaling.Adenosine 5'-monophosphate-activated protein kinase promotes macrophage polarization to an anti-inflammatory functional phenotype.Activation of AMP-activated protein kinase suppresses oxidized low-density lipoprotein-induced macrophage proliferation.Protective benefits of AMP-activated protein kinase in hepatic ischemia-reperfusion injury.Exploiting the anti-inflammatory effects of AMP-activated protein kinase activation.AMP-activated protein kinase: new regulation, new roles?The AMPK enzyme-complex: from the regulation of cellular energy homeostasis to a possible new molecular target in the management of chronic inflammatory disorders.Blockade of reactive oxygen species and Akt activation is critical for anti-inflammation and growth inhibition of metformin in phosphatase and tensin homolog-deficient RAW264.7 cells.AICAR induces astroglial differentiation of neural stem cells via activating the JAK/STAT3 pathway independently of AMP-activated protein kinase.AMPK Activation by A-769662 Controls IL-6 Expression in Inflammatory Arthritis.Suppressive effect of AMP-activated protein kinase on the epithelial-mesenchymal transition in retinal pigment epithelial cells.Activation of AMPK inhibits inflammation in MRL/lpr mouse mesangial cells.Adiponectin inhibits LPS-induced NF-kappaB activation and IL-6 production and increases PPARgamma2 expression in adipocytes.Repression of protein synthesis and mTOR signaling in rat liver mediated by the AMPK activator aminoimidazole carboxamide ribonucleoside.AICAR suppresses TNF-α-induced complement factor B in RPE cells.
P2860
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P2860
5-Aminoimidazole-4-carboxamide riboside suppresses lipopolysaccharide-induced TNF-alpha production through inhibition of phosphatidylinositol 3-kinase/Akt activation in RAW 264.7 murine macrophages.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
5-Aminoimidazole-4-carboxamide ...... RAW 264.7 murine macrophages.
@en
type
label
5-Aminoimidazole-4-carboxamide ...... RAW 264.7 murine macrophages.
@en
prefLabel
5-Aminoimidazole-4-carboxamide ...... RAW 264.7 murine macrophages.
@en
P2093
P1476
5-Aminoimidazole-4-carboxamide ...... RAW 264.7 murine macrophages.
@en
P2093
Hyung Hwan Baik
Insug Kang
Quanri Jin
Sung Soo Kim
Yong Ho Cho
Young Taek Oh
P304
P356
10.1016/J.BBRC.2004.04.035
P577
2004-05-01T00:00:00Z