Microarray expression profiling in melanoma reveals a BRAF mutation signature.
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Intra-lesional injection of the novel PKC activator EBC-46 rapidly ablates tumors in mouse modelsNVP-LDE225, a potent and selective SMOOTHENED antagonist reduces melanoma growth in vitro and in vivoSomatic mutations in MAP3K5 attenuate its proapoptotic function in melanoma through increased binding to thioredoxinCharacterization of the Melanoma miRNAome by Deep SequencingBRAF vs RAS oncogenes: are mutations of the same pathway equal? Differential signalling and therapeutic implicationsGene Expression Profiling of Primary Cutaneous Melanoma and Clinical OutcomeMultiple types of data are required to identify the mechanisms influencing the spatial expansion of melanoma cell colonies.Accounting for one-channel depletion improves missing value imputation in 2-dye microarray dataImproving missing value imputation of microarray data by using spot quality weights.Expression profiling identifies genes involved in neoplastic transformation of serous ovarian cancer.Distinct patterns of DNA copy number alterations associate with BRAF mutations in melanomas and melanoma-derived cell linesCross-platform array screening identifies COL1A2, THBS1, TNFRSF10D and UCHL1 as genes frequently silenced by methylation in melanoma.Histone deacetylase inhibitor-temozolomide co-treatment inhibits melanoma growth through suppression of Chemokine (C-C motif) ligand 2-driven signals.Critical role of STAT3 in melanoma metastasis through anoikis resistanceOncogenic codon 13 NRAS mutation in a primary mesenchymal brain neoplasm and nevus of a child with neurocutaneous melanosis.Cutaneous melanoma: prognostic factors.A new transgenic mouse line for tetracycline inducible transgene expression in mature melanocytes and the melanocyte stem cells using the Dopachrome tautomerase promoter.Transcriptome profiling identifies HMGA2 as a biomarker of melanoma progression and prognosis.Can systems biology understand pathway activation? Gene expression signatures as surrogate markers for understanding the complexity of pathway activation.BMCC1 is an AP-2 associated endosomal protein in prostate cancer cellsDecreased expression of nuclear p300 is associated with disease progression and worse prognosis of melanoma patientsClinically relevant genes and regulatory pathways associated with NRASQ61 mutations in melanoma through an integrative genomics approach.High efficiency ex vivo cloning of antigen-specific human effector T cellsSema6A and Mical1 control cell growth and survival of BRAFV600E human melanoma cells.Global comparative gene expression analysis of melanoma patient samples, derived cell lines and corresponding tumor xenografts.Activation of the extracellular signal regulated kinase (ERK) pathway in human melanoma.Plexin B1 is repressed by oncogenic B-Raf signaling and functions as a tumor suppressor in melanoma cellsA novel recurrent mutation in MITF predisposes to familial and sporadic melanoma.Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing.Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activity.The immune-related role of BRAF in melanoma.Functional informatics: convergence and integration of automation and bioinformatics.Sensitivity to the MEK inhibitor E6201 in melanoma cells is associated with mutant BRAF and wildtype PTEN statusBRAF(E600) in benign and malignant human tumours.p16INK4a expression and absence of activated B-RAF are independent predictors of chemosensitivity in melanoma tumorsTreatment of B-RAF mutant human tumor cells with a MEK inhibitor requires Bim and is enhanced by a BH3 mimetic.DNA microarray analyses of melanoma gene expression: a decade in the mines.Understanding signaling cascades in melanomaGrowth factors and oncogenes as targets in melanoma: lost in translation?RAF265 inhibits the growth of advanced human melanoma tumors.
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P2860
Microarray expression profiling in melanoma reveals a BRAF mutation signature.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Microarray expression profiling in melanoma reveals a BRAF mutation signature.
@en
type
label
Microarray expression profiling in melanoma reveals a BRAF mutation signature.
@en
prefLabel
Microarray expression profiling in melanoma reveals a BRAF mutation signature.
@en
P2093
P2860
P4510
P50
P356
P1433
P1476
Microarray expression profiling in melanoma reveals a BRAF mutation signature
@en
P2093
Graeme J Walker
Jennifer Taylor
Katherine Hansen
Kay A O Ellem
Laura Yudt
Leisl Packer
Michael G E O'Rourke
Nicholas K Hayward
Paul Meltzer
Peter Hersey
P2860
P2888
P304
P356
10.1038/SJ.ONC.1207563
P407
P50
P577
2004-05-01T00:00:00Z
P5875
P6179
1036495589