Critical role for hematopoietic cell kinase (Hck)-mediated phosphorylation of Gab1 and Gab2 docking proteins in interleukin 6-induced proliferation and survival of multiple myeloma cells.
about
Acetylcholinesterase-R increases germ cell apoptosis but enhances sperm motilityUp-regulation of bone marrow stromal protein 2 (BST2) in breast cancer with bone metastasis.Laser capture microdissection and genetic analysis of carbon-labeled Kupffer cells.Altered glucose homeostasis in mice with liver-specific deletion of Src homology phosphatase 2Disruption of Src function potentiates Chk1-inhibitor-induced apoptosis in human multiple myeloma cells in vitro and in vivo.The small-molecule VEGF receptor inhibitor pazopanib (GW786034B) targets both tumor and endothelial cells in multiple myeloma.Adipose-specific deletion of Src homology phosphatase 2 does not significantly alter systemic glucose homeostasis.Involvement of the HCK and FGR src-family kinases in FCRL4-mediated immune regulationA novel Stat3 binding motif in Gab2 mediates transformation of primary hematopoietic cells by the Stk/Ron receptor tyrosine kinase in response to Friend virus infectionHematopoietic cell kinase (HCK) as a therapeutic target in immune and cancer cells.Targeting signalling pathways for the treatment of multiple myeloma.Anaplastic plasmacytomas: relationships to normal memory B cells and plasma cell neoplasms of immunodeficient and autoimmune mice.Bone marrow microenvironment and the identification of new targets for myeloma therapy.Genetic modification of hematopoietic stem cells with nonviral systems: past progress and future prospects.Absence of SKP2 expression attenuates BCR-ABL-induced myeloproliferative diseaseSrc as the link between inflammation and cancer.Modulation of natural killer cell effector functions through lenalidomide/dasatinib and their combined effects against multiple myeloma cells.Mechanisms of Resistance in Multiple Myeloma.Differential phosphorylation of the docking protein Gab1 by c-Src and the hepatocyte growth factor receptor regulates different aspects of cell functions.Gab adapter proteins as therapeutic targets for hematologic disease.Gab2 and Src co-operate in human mammary epithelial cells to promote growth factor independence and disruption of acinar morphogenesis.Activated STAT5 proteins induce activation of the PI 3-kinase/Akt and Ras/MAPK pathways via the Gab2 scaffolding adapter.Essential role of EBF1 in the generation and function of distinct mature B cell types.Dasatinib in relapsed or plateau-phase multiple myeloma.Imatinib mesylate inhibits proliferation of rheumatoid synovial fibroblast-like cells and phosphorylation of Gab adapter proteins activated by platelet-derived growth factor.
P2860
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P2860
Critical role for hematopoietic cell kinase (Hck)-mediated phosphorylation of Gab1 and Gab2 docking proteins in interleukin 6-induced proliferation and survival of multiple myeloma cells.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Critical role for hematopoieti ...... val of multiple myeloma cells.
@en
type
label
Critical role for hematopoieti ...... val of multiple myeloma cells.
@en
prefLabel
Critical role for hematopoieti ...... val of multiple myeloma cells.
@en
P2093
P2860
P356
P1476
Critical role for hematopoieti ...... ival of multiple myeloma cells
@en
P2093
Dharminder Chauhan
Klaus Podar
Laurence P Catley
Martin Sattler
Richard C Mulligan
Teru Hideshima
Toshiaki Hayashi
Yu-Tzu Tai
P2860
P304
21658-21665
P356
10.1074/JBC.M305783200
P407
P577
2004-03-09T00:00:00Z