Somatic mitochondrial DNA mutations in cortex and substantia nigra in aging and Parkinson's disease.
about
Autophagy, mitochondria and oxidative stress: cross-talk and redox signallingMitochondrial DNA damage patterns and aging: revising the evidences for humans and miceDynamics of Human Mitochondrial Complex I Assembly: Implications for Neurodegenerative DiseasesMitochondrial defects and oxidative stress in Alzheimer disease and Parkinson diseaseMaternal inheritance and mitochondrial DNA variants in familial Parkinson's diseaseLysosomal function in macromolecular homeostasis and bioenergetics in Parkinson's disease.Somatic mitochondrial DNA mutations in early Parkinson and incidental Lewy body disease.Mitochondrial dysfunction in Parkinson's disease: pathogenesis and neuroprotection.Development of Therapeutics That Induce Mitochondrial Biogenesis for the Treatment of Acute and Chronic Degenerative Diseases.Cell and animal models of mtDNA biology: progress and prospects.The unusual amino acid L-ergothioneine is a physiologic cytoprotectantMitochondrial Dysfunction and Oxidative Stress in Asthma: Implications for Mitochondria-Targeted Antioxidant TherapeuticsRoles of cholesterol and lipids in the etiopathogenesis of Alzheimer's disease.Mitochondrial Dysfunction during Brain Aging: Role of Oxidative Stress and Modulation by Antioxidant Supplementation.Mechanisms linking mtDNA damage and aging.Exploring the link between glucocerebrosidase mutations and parkinsonismRole and treatment of mitochondrial DNA-related mitochondrial dysfunction in sporadic neurodegenerative diseases.Single-molecule PCR: an artifact-free PCR approach for the analysis of somatic mutations.Tissue-specific implications of mitochondrial alterations in aging.Mitoenergetic failure in Alzheimer disease.Somatic mtDNA variation is an important component of Parkinson's disease.Mitochondrial DNA mutations and aging.Does mitochondrial DNA play a role in Parkinson's disease? A review of cybrid and other supportive evidence.Mitochondrial DNA oxidative damage and repair in aging and Alzheimer's disease.The mitochondrial impairment, oxidative stress and neurodegeneration connection: reality or just an attractive hypothesis?The Alzheimer's disease mitochondrial cascade hypothesis: an updateMitochondrial approaches for neuroprotectionMitochondrial kinases in Parkinson's disease: converging insights from neurotoxin and genetic modelsThe impact of mitochondrial DNA and nuclear genes related to mitochondrial functioning on the risk of Parkinson's disease.Mitochondria-targeted antioxidants for treatment of Parkinson's disease: preclinical and clinical outcomes.The centrality of mitochondria in the pathogenesis and treatment of Parkinson's disease.The role of DNA base excision repair in brain homeostasis and disease.Chronic oxidative damage together with genome repair deficiency in the neurons is a double whammy for neurodegeneration: Is damage response signaling a potential therapeutic target?Post-Translational Oxidative Modifications of Mitochondrial Complex I (NADH: Ubiquinone Oxidoreductase): Implications for Pathogenesis and Therapeutics in Human Diseases.DNA damage induces nuclear translocation of parkin.Cdk5-Dependent Activation of Neuronal Inflammasomes in Parkinson's Disease.Do somatic mitochondrial DNA mutations contribute to Parkinson's disease?Mitochondrial DNA mutations in Parkinson's disease brain.Response to Simon et al.Does premature aging of the mtDNA mutator mouse prove that mtDNA mutations are involved in natural aging?
P2860
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P2860
Somatic mitochondrial DNA mutations in cortex and substantia nigra in aging and Parkinson's disease.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Somatic mitochondrial DNA muta ...... aging and Parkinson's disease.
@en
type
label
Somatic mitochondrial DNA muta ...... aging and Parkinson's disease.
@en
prefLabel
Somatic mitochondrial DNA muta ...... aging and Parkinson's disease.
@en
P2093
P921
P1476
Somatic mitochondrial DNA muta ...... aging and Parkinson's disease.
@en
P2093
Colette H Ahn
David K Simon
Donald R Johns
Florence Twu
Guang-Jun Liu
Lauren M Kim
Leiya Zheng
M Flint Beal
Michael T Lin
William M Mauck
P356
10.1016/S0197-4580(03)00037-X
P577
2004-01-01T00:00:00Z