Mexiletine block of wild-type and inactivation-deficient human skeletal muscle hNav1.4 Na+ channels.
about
Genetic neurological channelopathies: molecular genetics and clinical phenotypes.Mexiletine is an effective antimyotonia treatment in myotonic dystrophy type 1.Block of inactivation-deficient Na+ channels by local anesthetics in stably transfected mammalian cells: evidence for drug binding along the activation pathway.Mexiletine for symptoms and signs of myotonia in nondystrophic myotonia: a randomized controlled trialRegulation of CLC-1 chloride channel biosynthesis by FKBP8 and Hsp90β.Persistent human cardiac Na+ currents in stably transfected mammalian cells: Robust expression and distinct open-channel selectivity among Class 1 antiarrhythmics.Skeletal muscle na channel disorders.Preclinical evaluation of marketed sodium channel blockers in a rat model of myotonia discloses promising antimyotonic drugs.Biophysical characterization of M1476I, a sodium channel founder mutation associated with cold-induced myotonia in French Canadians.Bupivacaine blocks N-type inactivating Kv channels in the open state: no allosteric effect on inactivation kinetics.Mechanism of sodium channel block by local anesthetics, antiarrhythmics, and anticonvulsants.Mexiletine for treatment of myotonia: a trial triumph for rare disease networks.Molecular basis for class Ib anti-arrhythmic inhibition of cardiac sodium channels.Anesthetic management for subtotal gastrectomy in a patient with paramyotonia congenita.Lacosamide Inhibition of Nav1.7 Voltage-Gated Sodium Channels: Slow Binding to Fast-Inactivated States.
P2860
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P2860
Mexiletine block of wild-type and inactivation-deficient human skeletal muscle hNav1.4 Na+ channels.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Mexiletine block of wild-type ...... l muscle hNav1.4 Na+ channels.
@en
type
label
Mexiletine block of wild-type ...... l muscle hNav1.4 Na+ channels.
@en
prefLabel
Mexiletine block of wild-type ...... l muscle hNav1.4 Na+ channels.
@en
P2093
P2860
P1476
Mexiletine block of wild-type ...... l muscle hNav1.4 Na+ channels.
@en
P2093
Corinna Russell
Ging Kuo Wang
Sho-Ya Wang
P2860
P304
P356
10.1113/JPHYSIOL.2003.054973
P407
P577
2003-11-07T00:00:00Z