Inhibition of sodium currents by local anesthetics in chloramine-T-treated squid axons. The role of channel activation.
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Role of voltage-gated sodium, potassium and calcium channels in the development of cocaine-associated cardiac arrhythmiasIndoxacarb, an oxadiazine insecticide, blocks insect neuronal sodium channelsProtective effects of antiarrhythmic agents against anoxic injury in CNS white matterTetrapentylammonium block of chloramine-T and veratridine modified rat brain type IIA sodium channelsModification of cardiac Na+ channels by batrachotoxin: effects on gating, kinetics, and local anesthetic binding.QX-314 restores gating charge immobilization abolished by chloramine-T treatment in squid giant axons.Kinetic analysis of phasic inhibition of neuronal sodium currents by lidocaine and bupivacaineIsoform-specific lidocaine block of sodium channels explained by differences in gatingResidues in Na(+) channel D3-S6 segment modulate both batrachotoxin and local anesthetic affinities.Molecular mechanism of allosteric modification of voltage-dependent sodium channels by local anestheticsUse-dependent block of single sodium channels by lidocaine in guinea pig ventricular myocytes.Anoxic and ischemic injury of myelinated axons in CNS white matter: from mechanistic concepts to therapeutics.Characterization of concentration- and use-dependent effects of quinidine from conduction delay and declining conduction velocity in canine Purkinje fibers.Sodium channel inactivation: molecular determinants and modulation.Voltage-sensitive sodium channels: agents that perturb inactivation gating.Binding of benzocaine in batrachotoxin-modified Na+ channels. State-dependent interactions.The position of the fast-inactivation gate during lidocaine block of voltage-gated Na+ channelsBlock of brain sodium channels by peptide mimetics of the isoleucine, phenylalanine, and methionine (IFM) motif from the inactivation gateBlock of inactivation-deficient Na+ channels by local anesthetics in stably transfected mammalian cells: evidence for drug binding along the activation pathway.Antagonism of lidocaine inhibition by open-channel blockers that generate resurgent Na current.Novel molecular determinants in the pore region of sodium channels regulate local anesthetic binding.Persistent human cardiac Na+ currents in stably transfected mammalian cells: Robust expression and distinct open-channel selectivity among Class 1 antiarrhythmics.Block of wild-type and inactivation-deficient cardiac sodium channels IFM/QQQ stably expressed in mammalian cells.Mexiletine block of wild-type and inactivation-deficient human skeletal muscle hNav1.4 Na+ channels.State-Dependent Inhibition of Sodium Channels by Local Anesthetics: A 40-Year Evolution.Bupivacaine blocks N-type inactivating Kv channels in the open state: no allosteric effect on inactivation kinetics.Mechanism of inhibition of the sodium current by bepridil in guinea-pig isolated ventricular cells.Cocaine binds to a common site on open and inactivated human heart (Na(v)1.5) sodium channels.Lidocaine selectively blocks abnormal impulses arising from noninactivating Na channels.Sometimes you see them, sometimes you don't: IPSCs in the rat superficial superior colliculus.Compound-specific Na+ channel pore conformational changes induced by local anaesthetics.Quaternary ammonium block of mutant Na+ channels lacking inactivation: features of a transition-intermediate mechanism.Ion transport and membrane potential in CNS myelinated axons. II. Effects of metabolic inhibition.Comparative inhibition of voltage-gated cation channels by local anesthetics.
P2860
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P2860
Inhibition of sodium currents by local anesthetics in chloramine-T-treated squid axons. The role of channel activation.
description
1987 nî lūn-bûn
@nan
1987年の論文
@ja
1987年学术文章
@wuu
1987年学术文章
@zh-cn
1987年学术文章
@zh-hans
1987年学术文章
@zh-my
1987年学术文章
@zh-sg
1987年學術文章
@yue
1987年學術文章
@zh
1987年學術文章
@zh-hant
name
Inhibition of sodium currents ...... he role of channel activation.
@ast
Inhibition of sodium currents ...... he role of channel activation.
@en
type
label
Inhibition of sodium currents ...... he role of channel activation.
@ast
Inhibition of sodium currents ...... he role of channel activation.
@en
prefLabel
Inhibition of sodium currents ...... he role of channel activation.
@ast
Inhibition of sodium currents ...... he role of channel activation.
@en
P2093
P2860
P356
P1476
Inhibition of sodium currents ...... he role of channel activation.
@en
P2093
G R Strichartz
M S Brodwick
P2860
P304
P356
10.1085/JGP.89.4.645
P577
1987-04-01T00:00:00Z