Hypermethylation of telomere-like foldbacks at codon 12 of the human c-Ha-ras gene and the trinucleotide repeat of the FMR-1 gene of fragile X.
about
Fragile X (CGG)n repeats induce a transcriptional repression in cis upon a linked promoter: evidence for a chromatin mediated effectTransgene-induced CCWGG methylation does not alter CG methylation patterning in human kidney cells.Fragile X spectrum disordersRepeat-mediated genetic and epigenetic changes at the FMR1 locus in the Fragile X-related disordersStructures of the potassium-saturated, 2:1, and intermediate, 1:1, forms of a quadruplex DNATranscription-associated R-loop formation across the human FMR1 CGG-repeat regionDNA methylation: past, present and future directions.Unusual mutations in high functioning fragile X males: apparent instability of expanded unmethylated CGG repeats.DNA methylation in eukaryotic chromosome stability revisited: DNA methyltransferase in the management of DNA conformation space.Successful computational prediction of novel imprinted genes from epigenomic features.Hairpins are formed by the single DNA strands of the fragile X triplet repeats: structure and biological implications.Secondary structure at a hot spot for DNA methylation in DNA from human breast cancers.Expanded CTG repeat demarcates a boundary for abnormal CpG methylation in myotonic dystrophy patient tissuesMethylation of slipped duplexes, snapbacks and cruciforms by human DNA(cytosine-5)methyltransferase.Dynamic interrelationships between DNA replication, methylation, and repairRepeat-mediated epigenetic dysregulation of the FMR1 gene in the fragile X-related disorders.Altered DNA methylation and genome instability: a new pathway to cancer?Reactivation of FMR1 by CRISPR/Cas9-Mediated Deletion of the Expanded CGG-Repeat of the Fragile X Chromosome.Chromatin remodeling in the noncoding repeat expansion diseases.The biological effects of simple tandem repeats: lessons from the repeat expansion diseases.Genome-wide colonization of gene regulatory elements by G4 DNA motifsHMG box proteins interact with multiple tandemly repeated (GCC)n (GGC)m DNA sequences.The cationic porphyrin TMPyP4 destabilizes the tetraplex form of the fragile X syndrome expanded sequence d(CGG)n.A potent cell-active allosteric inhibitor of murine DNA cytosine C5 methyltransferase.The fragile X chromosome (GCC) repeat folds into a DNA tetraplex at neutral pH.Position-dependent methylation and transcriptional silencing of transgenes in inverted T-DNA repeats: implications for posttranscriptional silencing of homologous host genes in plants.In vitro expansion of GGC:GCC repeats: identification of the preferred strand of expansion.Trinucleotide repeats associated with human diseaseEffect of in vitro promoter methylation and CGG repeat expansion on FMR-1 expression.Neighboring base damage induced by permanganate oxidation of 8-oxoguanine in DNA.Compact structures of d(CNG)n oligonucleotides in solution and their possible relevance to fragile X and related human genetic diseasesMaintaining the unmethylated state.The DMPK gene of severely affected myotonic dystrophy patients is hypermethylated proximal to the largely expanded CTG repeat.The effects of trinucleotide repeats found in human inherited disorders on palindrome inviability in Escherichia coli suggest hairpin folding preferences in vivo.Mouse DNA methyltransferase (MTase) deletion mutants that retain the catalytic domain display neither de novo nor maintenance methylation activity in vivo.
P2860
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P2860
Hypermethylation of telomere-like foldbacks at codon 12 of the human c-Ha-ras gene and the trinucleotide repeat of the FMR-1 gene of fragile X.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Hypermethylation of telomere-l ...... f the FMR-1 gene of fragile X.
@en
type
label
Hypermethylation of telomere-l ...... f the FMR-1 gene of fragile X.
@en
prefLabel
Hypermethylation of telomere-l ...... f the FMR-1 gene of fragile X.
@en
P2093
P356
P1476
Hypermethylation of telomere-l ...... f the FMR-1 gene of fragile X.
@en
P2093
P304
P356
10.1006/JMBI.1994.1640
P407
P577
1994-10-01T00:00:00Z